Top Remote IT Jobs in Charleston, SC

Lead delivery and oversight of internal and client projects, ensuring on-time, on-budget completion. Manage resources, risks, scope, finances, stakeholders, vendor relationships, project documentation, performance tracking, and reporting. Apply project management methodologies (Agile/Waterfall) and leverage AI platforms to increase efficiency.

Build and maintain internal platforms, automations, and integrations to scale IT operations. Own identity, access, lifecycle automation, endpoint trust, SaaS provisioning, and operational reporting. Develop scripts and services (Python, Bash), partner with Security and Engineering for secure AI, Zero Trust, HIPAA and SOC 2 compliance, and apply DevOps/SRE/ITIL practices for monitoring and incident response.

Serve as Product Owner for Oracle/Cerner clinical solutions, partnering with clinical stakeholders and technical teams to define requirements, manage backlogs, configure and validate clinical content, support enterprise deployment and standardization, and drive adoption, testing, and optimization across the product lifecycle.

Provide onboard IT systems support, maintenance, monitoring, backups, inventory, hardware shipping/receiving, equipment repairs, user support and training, and escalate issues to the IT Officer while maintaining security and service standards.

Lead and execute IT audit engagements across APAC, evaluating IT infrastructure, cybersecurity, applications, and controls. Use data analytics to design and perform data-driven audit procedures, validate remediation, prepare audit reports and working papers, support continuous auditing and automation, and collaborate with regional/global audit teams and governance forums.

The Project & IT Budget Analyst manages project coordination and IT budget oversight, supporting strategic initiatives and ensuring financial accuracy.

Lead CPIC activities for OCSE: prepare IT portfolio submissions, ensure compliance with OMB/HHS/ACF reporting, support EVM and performance management, coordinate stakeholders, develop templates/processes, produce analyses and executive briefings, and support budget and risk reporting.

Define and execute enterprise strategy for data, analytics, AI, automation, and innovation. Build data governance, architecture, engineering, BI, and AI adoption (including Generative and Agentic AI). Identify high-value use cases, scale emerging technologies, partner with IT functions, lead high-performing teams, advise executives and board-level stakeholders, and ensure security, privacy, governance, and responsible AI compliance.

The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.

The Senior IT Risk and Compliance Analyst manages vendor risk, ensures compliance with regulations, documents controls, and supports risk mitigation efforts across IT teams.

The IT Systems Engineer will manage IT operations, support M&A integrations, and optimize Microsoft cloud systems, ensuring reliability and security.

Lead global IT strategy and operations for a life‑sciences CRO: oversee cloud and infrastructure, cybersecurity and compliance (GxP/21 CFR/GDPR), enterprise applications and data strategy, digital transformation, vendor and budget management, and build a global IT organization to enable clinical research, data science, and product delivery.

Lead and grow the IT Engineering team while hands-on securing endpoints, offices, networks, and SaaS tools. Implement automation-first workflows (scripting, IaC), manage MDM and identity systems, support office buildouts, ensure SOC 2/ISO 27001 compliance, mentor engineers, and collaborate with Security and Operations.

Drive net-new enterprise IT services revenue by owning full sales lifecycle: prospecting, executive engagement, solution positioning, collaboration with presales/delivery, pipeline management, and closing multi-year managed services, application modernization, and digital transformation deals to meet $5M–$10M annual targets.

As a Senior IT FP&A Technology Product Owner, you will manage technology strategy and delivery for FP&A, oversee integrations and data architecture, and drive AI and automation within FP&A technology.

The IT Project Engineer is responsible for onboarding clients into Atlas Technica's support model, implementing secure solutions, and ensuring documentation meets compliance standards, while collaborating with other teams and providing oversight to junior engineers.

Manage AI/ML projects from Proof of Concept to Minimum Viable Product using Agile methodologies while ensuring stakeholder communication and project alignment.

The LN Support Analyst III provides support for LN Finance, ensuring effective implementation, end-user training, and process mapping while resolving user issues and documenting solutions.

The role involves managing user accounts, administering ITSM platforms, improving system performance, and providing technical support, focusing on IT service management best practices.

Design, develop, test, deploy, and maintain enterprise Java applications for USPS. Build RESTful APIs with Spring, translate requirements into architecture, implement CI/CD/DevSecOps, integrate relational databases, troubleshoot complex issues, and collaborate with cross-functional Agile teams to deliver high-quality software solutions.

Senior UI/UX specialist responsible for human-centered design, user research, prototyping, usability testing, and delivering detailed interface specifications. Leads UX strategy, creates personas, journey maps, dynamic forms, and accessibility-compliant designs, and partners with product and development teams to implement React/JS front-end solutions within a microservice architecture.

Lead end-to-end IT sourcing for hardware, software, SaaS, and security services. Develop sourcing strategies, run RFx and negotiations, draft and manage contracts, perform market and TCO analysis, mitigate risks, manage supplier performance, and align cross-functional stakeholders to optimize cost, performance, and vendor portfolios.

Lead IT sourcing for applications, software, cloud services and consulting. Develop sourcing strategies, run RFP/RFI, manage vendor relationships and performance, negotiate contracts, analyze spend for cost savings, ensure regulatory compliance (medical device, data privacy), and collaborate with IT, Finance, Legal and business stakeholders to deliver required IT resources.

Senior GCP Engineer will design, deploy, and operate scalable GCP infrastructure, enable DevSecOps and IaC (Terraform), support AI/ML workloads (Vertex AI, BigQuery ML), manage networking, security, and governance, collaborate across multi-cloud teams, and produce architecture and implementation documentation.

Manage multi-site IT support operations for a manufacturing organization: lead L1/L2 teams, resolve hardware/software issues, oversee infrastructure, enforce cybersecurity, coordinate vendors, manage imaging and deployments, document systems, and align IT with production goals.