Top Senior Data Science Jobs in Louisville, KY

29 Days AgoSaved
Remote
Louisville, KY
130K-150K Annually
Senior level
130K-150K Annually
Senior level
Information Technology • Consulting
Build production AI retrieval and knowledge systems for rare disease research at NIH. Model biomedical ontologies in PostgreSQL, develop semantic search, retrieval-augmented services, ranking, evaluation, and observability, and deliver user interfaces with Next.js, React, and TypeScript. Deploy and operate services in on-premises and HPC Kubernetes environments, including GPU inference. Collaborate with NIH staff, clinicians, and researchers, and contribute to scientific publications.
Top Skills: Ci/CdDockerFastapiFull-Text SearchGa4GhGitHelmHpoKubernetesLitellmLlm ApisMedcptMeshMondoNext.JsObo FoundryOllamaPgvectorPostgresPydanticPytestPythonReactStatefulsetsTypescriptUmlsVllm
29 Days AgoSaved
Remote
Louisville, KY
130K-150K Annually
Senior level
130K-150K Annually
Senior level
Information Technology • Consulting
Build and operate agentic AI systems for rare disease research, including multi-turn workflows, structured and validated outputs, tool calling, prompt testing, evaluation suites, asynchronous execution, streaming, observability, and failure handling. Collaborate with NIH staff, clinicians, geneticists, researchers, and patient communities to translate needs into reliable data models and system behavior. Own components through deployment, establish AI engineering standards, and contribute to scientific manuscripts, abstracts, and conference posters.
Top Skills: Anthropic Agent SdkArize PhoenixAsynchronous PythonBraintrustCi/CdConcurrent PythonDockerFastapiGitHpoKubernetesLangfuseLanggraphLangsmithLitellmLlm ApisMcpMeshMondoObo FoundryOllamaOpenai Agent SdkPostgresPydanticPydantic AiPytestPythonStreamingStructured GenerationTool CallingUmlsVector SearchVllm
Reposted One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Artificial Intelligence • Healthtech • Machine Learning
Develop and tune ML models, productionize and deploy strategies for ML systems, and align cross-functionally to communicate performance metrics.
Top Skills: PysparkPythonPyTorchSQL
Reposted One Month AgoSaved
In-Office or Remote
Louisville, KY
105K-105K Annually
Senior level
105K-105K Annually
Senior level
Travel
Lead end-to-end machine learning and advanced analytics projects: frame problems, build and deploy predictive/prescriptive models, design ETL pipelines, create dashboards and A/B test metrics, and deliver actionable insights to business stakeholders to improve fleet, pricing, and ridesharing products.
Top Skills: BigQueryDatabricksETLEvent-Driven ArchitecturesPythonSQLStreaming DataTableau
One Month AgoSaved
Remote
Louisville, KY
135K-165K Annually
Senior level
135K-165K Annually
Senior level
eCommerce • Insurance • Software
Lead end-to-end development of fraud and risk ML systems: define problems, engineer features, build and evaluate models, collaborate with product and engineering, deploy with ML engineers, and monitor production performance to detect drift and trigger retraining.
Top Skills: PythonPyTorchScikit-LearnSQLXgboost
Reposted One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Machine Learning • Software
As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.
Top Skills: LlmMlSQL
Reposted One Month AgoSaved
Remote
Louisville, KY
140K-240K Annually
Senior level
140K-240K Annually
Senior level
Greentech
As a Data Scientist, you will build predictive models, develop software tools, and analyze geoscientific data to support mineral exploration and discovery.
Top Skills: Cicd PipelinesCloud ComputingCollaborative Software DevelopmentData Science PackagesGeospatial AnalysesGitMachine LearningPythonVisualizations
Reposted One Month AgoSaved
Remote
Louisville, KY
140K-240K Annually
Senior level
140K-240K Annually
Senior level
Greentech
As a Data Scientist, you will develop predictive models, analyze geoscientific data, and collaborate with geoscientists to improve mineral exploration efforts.
Top Skills: Cloud ComputingGeospatial AnalysisPythonSoftware Engineering
One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Cybersecurity
Owns the end-to-end development of cybersecurity vulnerability and exploit prediction models, including problem framing, feature engineering, training, evaluation, deployment, calibration, monitoring, and drift detection. The role addresses extreme class imbalance, hierarchical modeling, cold-start customers, and uncertainty quantification. It also requires explaining model outputs to security executives, publishing methodologies and benchmarks, and partnering with engineering to deploy reliable production systems.
Top Skills: PythonSQL
Reposted One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
AdTech • Big Data • Consumer Web • Digital Media • Marketing Tech
Own end-to-end data science for a priority vertical (starting with Insurance): frame business problems, build and validate models, partner with ML engineering for deployment, monitor live ROAS performance, and drive measurable revenue and lead quality improvements.
Top Skills: AWSCollaborative FilteringDeep LearningEmbeddingsGoogle AdsLlmsLookerLtv ModelingMeta AdsMulti-Armed BanditPythonRanking AlgorithmsRecommendation SystemsReinforcement LearningSQL
Reposted One Month AgoSaved
Remote
Louisville, KY
183K-183K Annually
Senior level
183K-183K Annually
Senior level
Big Data • Machine Learning • Social Impact • Software
Lead end-to-end data science projects including predictive modeling, algorithm design, and data pipelines. Build campaign-focused models (turnout, partisanship), perform exploration and visualization, translate insights into memos/presentations, collaborate with engineering to productionize models, mentor junior data scientists, and prototype emerging AI solutions for product impact.
Top Skills: GitPythonSQL
Reposted One Month AgoSaved
Remote
Louisville, KY
185K-400K Annually
Senior level
185K-400K Annually
Senior level
Information Technology
Design, build, and own large-scale data pipelines and ML data curation for multimodal (text, image, audio, video) model training. Partner with research teams to ingest, label, filter, augment, store, and ensure dataset quality, compliance, and scalability. Optimize distributed data processing for training, prototype dataset tools, and integrate research advances into production systems.
Top Skills: AWSAzureGCPHadoopPysparkPythonRaySparkSQL
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Reposted One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Artificial Intelligence • Big Data • Internet of Things • Software
The Senior Data Scientist will lead innovative data science efforts, leveraging advanced analytics, visualization, and insights from complex datasets to boost productivity.
Top Skills: PythonRScalaSQL
One Month AgoSaved
Remote or Hybrid
Louisville, KY
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Artificial Intelligence • Big Data • Machine Learning • Analytics • Business Intelligence • Consulting • Generative AI
Lead predictive modeling and causal inference initiatives for clients, developing models from exploratory analysis through production deployment, monitoring, and retraining. Apply GLMs, econometric methods, uplift modeling, propensity methods, and deep-learning forecasting. Process large-scale data with SQL and Spark, build models in Python, improve production reliability, and communicate findings to technical and business stakeholders in a consulting environment.
Top Skills: SparkPythonSQL
One Month AgoSaved
Remote
Louisville, KY
148K-203K Annually
Senior level
148K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Build marketing data science models and decision systems for spend allocation, channel measurement, forecasting, experimentation, and growth optimization. Unify marketing, retail, revenue, and product data; develop dashboards and analytical products; apply AI/ML and causal inference; and translate complex analysis into actionable recommendations for executives and cross-functional teams. The role also includes improving data quality, mentoring, documentation, and technical leadership.
Top Skills: AWSDatabricksDbtLlmsPythonSnowflakeSQL
Reposted One Month AgoSaved
In-Office or Remote
Louisville, KY
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Digital Media • News + Entertainment • Business Intelligence
Lead data science work embedded in the newsroom: identify high-impact problems, build and productionize predictive and explanatory models, own core metrics/measurement, apply causal inference and experimentation, translate findings for senior stakeholders, and mentor junior data team members to improve analytic standards and adoption.
Top Skills: AirflowBigQueryDbtGitPythonSnowflakeSQL
Reposted One Month AgoSaved
Remote
Louisville, KY
76K-158K Annually
Senior level
76K-158K Annually
Senior level
Aerospace • Information Technology • Professional Services • Defense
Design and implement advanced ML models for real-time forecasting and decision support, ensure data provenance and lineage, integrate federated geospatial and multi-format data, produce ROM and quarterly cost/resource reports, and apply Agile sprint practices to deliver mission-aligned analytics for DoD/IC customers.
Top Skills: SparkDatabricksPythonPyTorchScikit-LearnTensorFlow
Reposted One Month AgoSaved
Remote
Louisville, KY
144K-299K Annually
Senior level
144K-299K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
As a Senior Data Scientist at Yahoo Mail, you will enhance user growth strategies via product innovation, overseeing research projects and analytics.
Top Skills: BigQueryHadoopHiveLookerPythonSparkSQLTableau
Reposted One Month AgoSaved
Remote
Louisville, KY
Senior level
Senior level
Healthtech
Build, ship, and own end-to-end ML models for vendor matching, order routing, and supply-chain optimization. Partner with data engineering to productionize models, quantify impact, document work, and implement decision logic components toward agentic AI in a fast-moving healthcare startup environment.
Top Skills: Agentic AiCausal InferenceGitMachine LearningOperations ResearchPythonReinforcement LearningSQL
Reposted One Month AgoSaved
Remote or Hybrid
Louisville, KY
Senior level
Senior level
Information Technology • Database • Consulting
Lead development of time-series and econometric models (ARIMA, VAR, state-space, WLS, panel data) and Bayesian probabilistic frameworks. Use causal inference and stochastic processes to produce actionable insights, work with large datasets on Databricks, communicate results to stakeholders, and mentor junior team members.
Top Skills: A/B TestingArimaBayesian ModelingCausal InferenceDatabricksMachine LearningMarkov ChainsMlopsPanel Data ModelsPythonSarimaSQLState-Space ModelsStochastic ProcessesVarWls
Reposted One Month AgoSaved
In-Office or Remote
Louisville, KY
Senior level
Senior level
Information Technology
Lead advanced analytics and ML projects: perform EDA, feature engineering, statistical modeling, and build/optimize production ML and Generative AI solutions (LLMs, embeddings, RAG). Collaborate with engineering and MLOps to deploy and monitor models, create visualizations and dashboards, translate insights for stakeholders, and mentor junior team members.
Top Skills: AWSAzureCi/CdDockerEmbeddingsGCPKubernetesLlmsMlflowMlopsPower BIPrompt EngineeringPythonPyTorchRagScikit-LearnSQLTableauTensorFlowXgboost
Reposted One Month AgoSaved
In-Office or Remote
Louisville, KY
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade generative AI applications: orchestrate multi-agent systems, implement advanced RAG with vector DBs, fine-tune and host LLMs, optimize GenAI workflows, and deliver scalable FastAPI-based backend services with Docker and monitoring.
Top Skills: Api SecurityAsynchronous ProgrammingCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal LlmsModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
Louisville, KY
71K-249K Annually
Senior level
71K-249K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector databases, integrate/benchmark LLMs, fine-tune models, and deploy scalable FastAPI-based services with monitoring, CI/CD, and Dockerized production pipelines.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Llm DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
Louisville, KY
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and scale production Generative AI systems: multi-agent orchestration, advanced RAG with vector databases, LLM integration and fine-tuning, scalable FastAPI backends, Dockerized deployment, monitoring, and GenAI optimization for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal Llm DeploymentMulti-Agent Systems (Mas)OpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
Louisville, KY
53K-188K Annually
Senior level
53K-188K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade generative AI systems: multi-agent orchestration, advanced RAG with vector databases, integrate/swap LLMs, fine-tune models, optimize prompts and latency, and containerize services with monitoring and CI/CD.
Top Skills: Api SecurityAsynchronous ProgrammingCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchQuantizationRagTensorFlowVector Databases
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