Top Senior IT Jobs in Des Moines, IA

Reposted 2 Months AgoSaved
Easy Apply
Remote
Des Moines, IA
Easy Apply
131K-154K Annually
Senior level
131K-154K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead end-to-end IT and security audits across cloud infrastructure, application security, IAM, vendor risk, and blockchain products. Plan and execute fieldwork, produce evidence-based reports for senior leaders and the Audit Committee, mentor junior auditors, validate remediation, and partner with Engineering and Security to improve controls while maintaining audit independence.
Top Skills: AWSBlockchainCobitCold StorageEncryptionGCPGenerative AiIdentity And Access Management (Iam)ItilLoggingNetwork ArchitectureNist CsfSoc 2Wallets
One Month AgoSaved
Remote
Des Moines, IA
63-83 Hourly
Senior level
63-83 Hourly
Senior level
Healthtech
Coordinates testing for Epic applications and integrated healthcare systems, including test planning, user acceptance testing, defect management, upgrades, implementations, documentation, and compliance. Provides tier-2 application support, resolves complex system issues, supports optimization and enhancements, collaborates with stakeholders and vendors, facilitates governance meetings, and mentors junior analysts. The role also requires advanced AI literacy, healthcare operations knowledge, and independent leadership across application support and delivery initiatives.
Top Skills: Azure DevopsDatabasesEpicExcelJIRAJob Scheduling ToolsMS OfficeMonitoring ToolsPowerPointScripting LanguagesServer Operating SystemsServicenowStorage SystemsVisioWordWorkday
One Month AgoSaved
Remote
Des Moines, IA
120K-140K Annually
Senior level
120K-140K Annually
Senior level
Consumer Web • Appliances
Drive sales growth for LG IT solutions across the Central Region through consultative selling, territory planning, account development, and partner collaboration. Build enterprise and commercial customer relationships, manage opportunities from discovery through close, coordinate pricing and forecasting, maintain Salesforce pipeline data, and achieve revenue and sales objectives. The role involves executive engagement, customer presentations, trade shows, and approximately 70–75% regional travel.
Top Skills: ExcelMS OfficeMicrosoft TeamsOutlookPowerPointSalesforce
One Month AgoSaved
Remote
Des Moines, IA
130K-180K Annually
Senior level
130K-180K Annually
Senior level
Cloud • Information Technology
Leads critical client escalations from initiation through closure, coordinating engineering, delivery, operations, and client success teams. Drives containment, root cause analysis, corrective actions, quality management, and continual improvement. Serves as the primary client advocate during high-visibility incidents, communicates with executives and clients, tracks resolution and satisfaction metrics, and presents performance insights to governance leaders. The role strengthens service delivery processes, prevents recurring issues, and promotes accountability and sustainable operational excellence.
Top Skills: AnalyticsAutomationCloud InfrastructureCorrective And Preventive Action (Capa)ItilLeanQuality Management Systems (Qms)Root Cause Analysis (Rca)Six Sigma
One Month AgoSaved
Remote
Des Moines, IA
152K-190K Annually
Senior level
152K-190K Annually
Senior level
Healthtech • Software • Pharmaceutical • Manufacturing
Leads global Workday platform strategy, governance, roadmap, delivery, and operational excellence. Manages Workday technical teams and offshore resources across HCM, talent, recruiting, payroll, integrations, reporting, security, and related modules. Partners with HR, Payroll, and Technology leaders to prioritize investments, oversee enhancements and transformations, manage vendors, budgets, contracts, and business cases, and ensure privacy, compliance, stability, and measurable business value.
Top Skills: APIsScrumWorkdayWorkday Absence ManagementWorkday CompensationWorkday HcmWorkday IntegrationsWorkday PayrollWorkday RecruitingWorkday Reporting And AnalyticsWorkday SecurityWorkday TalentWorkday Time Tracking
One Month AgoSaved
Remote
Des Moines, IA
208K-297K Annually
Senior level
208K-297K Annually
Senior level
Information Technology
Leads Docker’s global Information Technology organization, overseeing help desk services, application management, device lifecycle logistics, internal productivity tools, service metrics, SLAs, and continual improvement. Develops multi-year IT strategy and technology roadmaps, architects and optimizes the SaaS and cloud application ecosystem, manages technical debt, and partners with executives and technical leaders to support business growth. Builds a metrics-driven, customer-focused team and advances AI- and automation-first practices.
Top Skills: AIAutomationCloud InfrastructureSaaS
One Month AgoSaved
Remote
Des Moines, IA
111K-150K Annually
Senior level
111K-150K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Leads the surveying, design, installation, and implementation of telecommunications rooms and infrastructure at Eielson Air Force Base. Develops rack, cabling, grounding, electrical, cooling, and equipment layouts; manages government, contractor, and subcontractor installation teams; coordinates facility upgrades and network, fiber, ISP, and OSP integration; ensures compliance with DoD, UFC, TIA/EIA, and I3A standards; and supports design reviews and customer briefings.
Top Skills: Cat6Data Center InfrastructureDod Telecommunications StandardsFiber OpticI3A StandardsIdfMdfStructured CablingTelecommunications RoomsTia/Eia StandardsUfc StandardsUpsWi-Fi
One Month AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Agency • Marketing Tech
Lead administration of Microsoft 365, Google Workspace, SaaS applications, Azure identity, and cloud infrastructure in a fully cloud-based organization. Provide Level 2/3 service desk escalation, execute migrations and cybersecurity projects, establish IT service processes, manage assets and vendors, and support onboarding, offboarding, incident response, change management, and M&A initiatives. The role partners with IT leadership and may help build and manage a growing internal technical team.
Top Skills: AdobeAtlassianAzureClickupComptiaDnsDocusignEntra IdGamGoogle IdentityGoogle WorkspaceHubspotItilMicrosoft 365Microsoft 365 Powershell ModulesMonday.ComNetSuiteSalesforceScimSlackSsoZoom
One Month AgoSaved
Remote
Des Moines, IA
133K-178K Annually
Senior level
133K-178K Annually
Senior level
Biotech
Leads enterprise architecture for Biogen’s Veeva ecosystem across Development, Quality, Regulatory, Safety, and Commercial functions. Translates business needs into scalable Veeva configurations and integrations, governs target-state architecture and platform standards, reviews solution designs, and oversees implementation and release planning. Mentors configuration teams, drives cross-vault consistency, manages architecture governance, aligns with Veeva product roadmaps, and advises IT leadership on platform strategy, investments, regulatory compliance, and business objectives.
Top Skills: ArchimateCtmsEdcEtmfSafe ScrumTogafTrackwise QmsVeeva Vault
One Month AgoSaved
Remote
Des Moines, IA
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Cloud • Information Technology • Productivity • Security • Software
Leads the design, development, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system architecture blueprints, selects technologies, integrates distributed systems across on-premise and cloud environments, optimizes performance, ensures compliance with DoD requirements, and leads engineering teams. Diagnoses system issues, implements solutions, and produces architecture documentation while supporting installation, migration, and configuration activities across multiple client locations.
Top Skills: AbacAWSAzureC#CiscoCloud ComputingDod Zero Trust Execution RoadmapGCPHybrid CloudIcamJavaMicro-SegmentationNetwork Access ControlOn-PremisesPythonRed HatZero TrustZero Trust Network Architecture
One Month AgoSaved
Remote
Des Moines, IA
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Big Data • Cloud • Hardware • Software • App development
Leads the architecture, design, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system blueprints, selects technologies, integrates distributed systems across on-premises, cloud, and hybrid environments, optimizes performance, resolves system issues, and ensures compliance with DoD requirements. Leads engineering teams, supports installation and migration at multiple locations, and documents architecture and implementation decisions.
Top Skills: Attribute-Based Access Control (Abac)AWSC#Cloud ComputingDistributed SystemsGCPHybrid CloudIcamJavaMicro-SegmentationMicroservicesAzureNetwork Access ControlOn-Premises SystemsPythonZero TrustZero Trust Network Architecture
One Month AgoSaved
Remote or Hybrid
Des Moines, IA
Senior level
Senior level
Mobile • Security • Software • Cybersecurity
Leads complex federal platform, cloud infrastructure, IT services, security, compliance, and disaster recovery initiatives. Coordinates AWS GovCloud infrastructure-as-code, deployment automation, observability, Zero Trust identity programs, FedRAMP High and DoD IL5 readiness, and operational resilience. Partners across Engineering, Security, Compliance, and Product to manage roadmaps, dependencies, risks, milestones, and audit readiness. The role also builds and mentors a Federal Platform Operations team and drives reliable, repeatable delivery practices.
Top Skills: Amazon EcsAmazon EksAmazon RdsAmazon S3AWSAws GovcloudAws IamAws LambdaChatgptClaudeDatadogGrafanaKeeperpamPrometheusScimTerraform
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Reposted One Month AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Healthtech • Software • Automation
Sell radiology IT solutions by building strategic account plans, managing long technical sales cycles, maintaining a 3-5× quota pipeline, forecasting in Salesforce, partnering with marketing/inside sales, and representing the company at industry conferences.
Top Skills: Ai-Driven SolutionsMiller Heiman Blue SheetsMiller Heiman Strategic SellingPacsReporting WorkflowRisSalesforce
One Month AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Other
Leads business analysis for enterprise applications and reporting initiatives. Translates stakeholder needs into requirements and functional or technical specifications, partners with IT on scalable solutions, manages project scope and risks, maintains process documentation, supports UAT and change readiness, and drives process standardization. Establishes business analysis standards and best practices across a growing, multi-location organization.
Reposted One Month AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Retail • Sales
The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.
Top Skills: CertiniaCpqFinancialforcePower BISalesforceServicemaxSQLZuora
Reposted One Month AgoSaved
Remote
Des Moines, IA
91K-159K Annually
Senior level
91K-159K Annually
Senior level
Other • Retail
Lead a team to design, build, and operate scalable, secure platform and MLOps capabilities on GCP and hybrid cloud. Drive DevSecOps, CI/CD, telemetry, and platform modernization to accelerate AI/ML and software delivery while managing delivery, budgets, vendors, and stakeholder alignment.
Top Skills: AppdynamicsAzureBigQueryCi/CdDatadogDevsecopsGoogle Cloud Platform (Gcp)JavaMlopsPythonVertex Ai
Reposted One Month AgoSaved
Remote
Des Moines, IA
88K-135K Annually
Senior level
88K-135K Annually
Senior level
Consulting
The IT Project Manager will lead public sector ERP migration projects, ensuring high-quality deliverables and strategic alignment while collaborating with various stakeholders.
Top Skills: AgileBusiness IntelligenceCloud-Based ErpData AnalysisData MigrationIv&VPeoplesoftSap S/4Hana RiseSoftware DevelopmentWaterfall
One Month AgoSaved
Remote or Hybrid
Des Moines, IA
Senior level
Senior level
Software
Designs and operates IT services for laboratory environments, including networks, compute, security, private cloud, and SDN platforms. Translates business and IT requirements into secure, standardized architectures and operational processes. Leads deployments, design reviews, documentation, incident gap analysis, automation, and infrastructure optimization. Requires extensive enterprise networking, datacenter, virtualization, Linux, security, and ITIL experience.
Top Skills: AutomationBgpDhcpDnsFortinetInfrastructure As CodeIpsecIpv6ItilLinuxNokia Service RoutersNokia Sr LinuxOpenshiftOpenstackOrchestrationOspfPalo Alto FirewallsPrivate CloudProxmoxQosSoftware-Defined Networking (Sdn)TlsVMwareVrrpVxlan
One Month AgoSaved
Remote or Hybrid
Des Moines, IA
Senior level
Senior level
Software
Designs and operates laboratory IT services covering compute, networks, security, private and public cloud, and software-defined networking. Translates business requirements into secure, high-performance service offerings; defines architectures, configurations, processes, and operational procedures. Leads implementations, design reviews, documentation, incident analysis, gap remediation, automation, and infrastructure optimization across global laboratory environments.
Top Skills: AutomationBgpFortinetInfrastructure As CodeItilLinuxNokia Service RoutersNokia Sr LinuxOpenshiftOpenstackOrchestrationOspfPalo Alto FirewallsPrivate CloudProxmoxPublic CloudQosSoftware-Defined NetworkingVMwareVrrpVxlan
Reposted One Month AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Healthtech
Lead an Automation Center of Excellence to build and maintain IaC, automation pipelines, and configuration management across colo and multi-cloud (Azure, GCP, OCI). Drive standardization, governance, security controls, CI/CD integration, incident management, GitOps and policy-as-code adoption. Mentor team members, manage vendor relationships, measure automation KPIs, and provide executive reporting. Participate in on-call rotation and work outside normal hours as needed.
Top Skills: AnsibleArmAzureAzure DevopsBicepCi/CdGcp Deployment ManagerGitGithub ActionsGitopsGoogle Cloud Platform (Gcp)Infrastructure As Code (Iac)JenkinsObservabilityOci Resource ManagerOracle Cloud Infrastructure (Oci)Policy-As-CodeSecrets ManagementTerraform
Reposted One Month AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Healthtech
The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.
Top Skills: JIRAMs ProjectServicenow PpmSmartsheet
Reposted One Month AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Automation • Manufacturing
The IT Infrastructure Manager leads the infrastructure team, manages operations, and ensures secure, reliable systems while driving continuous improvement and aligning with business goals.
Top Skills: Active DirectoryAWSDhcpDnsExchangeFortinetGCPHyper-VMicrosoft 365AzureMicrosoft ServerOnedriveServersSharepointTeamsVirtualizationVMwareWindows Os
One Month AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Transportation • Energy • Utilities • Industrial
Drive national sales and account growth for IT cooling equipment, services, and software. Develop strategic customer relationships, pursue new business, manage channel partners, lead proposals and negotiations, forecast revenue, analyze market trends, and represent the company at industry events. The role requires technical knowledge of HVAC, mission-critical infrastructure, power quality, and data center solutions, along with strong commercial, communication, and relationship-management skills.
Top Skills: Critical PowerData Center InfrastructureHvacIt CoolingMS OfficePower QualitySalesforce
One Month AgoSaved
Remote
Des Moines, IA
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Design and develop scalable cloud applications using Node.js, microservices, Azure, and AWS. Build workflow, data integration, REST API, serverless, and event-driven solutions; integrate client applications with cloud storage; implement security, testing, CI/CD, and DevSecOps practices. Optimize performance and cost, collaborate with cross-functional teams, provide technical leadership and mentorship, conduct technology research, and communicate architecture and recommendations to stakeholders.
Top Skills: AgileAWSAzureAzure FunctionsCi/CdCosmos DbDatabricksDevsecopsDockerDocumentdbETLGCPGitKubernetesMicroservicesNode.jsOauth 2.0OcpReactRestful ApisSnowflakeSQLSwagger
One Month AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Healthtech • Software
Owns the company-wide IT and cybersecurity program, including SOC 2 compliance, cloud security, penetration-test remediation, business continuity testing, endpoint management, access controls, onboarding and offboarding, AI security governance, vendor reviews, security training, incident response, and employee IT support. The role partners with engineering, HR, Finance, leadership, auditors, and healthcare customers while managing security across AWS, Heroku, Cloudflare, Google Workspace, GitHub, and related tools.
Top Skills: 2FaAWSClaudeCloudflareCspmEdrGitGoogle WorkspaceGrcHerokuIamMcp ServersMdmRipplingSIEMSoc 2SsoVantaXdr
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