Maximum of 25 job preferences reached.
Top Senior Software Engineer Jobs in Charleston, SC
Artificial Intelligence • Software • Analytics • Financial Services
Lead development of AI-powered full-stack applications, mentor engineers, define technical direction, build performant front-end and scalable backend services, integrate LLMs/RAG, and establish engineering best practices for production AI workflows.
Top Skills:
AWSAzureGCPLlmsNode.jsPythonRagReactTypescript
Machine Learning • Software
Staff-level platform engineer to improve and scale inherited Scala systems, redesign data layers for ML/AI, build a Rust service framework, enhance observability and resilience, shape developer tooling and standards, and work across JVM, Rust, Python, SQL, and Spark.
Top Skills:
Distributed SystemsJavaJvmObservability And Resilience EngineeringPythonRustScalaSparkSQL
Software • Database
Design, build, and operate large-scale distributed web-crawling and data ingestion systems. Improve throughput, reliability, observability, and data quality. Develop backend services for job orchestration and asynchronous workloads, partner with product teams to create data products, and mentor teammates on domain-specific acquisition techniques.
Top Skills:
AirflowSparkAsync/AwaitAWSAzureBigQueryCliConcurrency FrameworksCoroutinesDatabricksDelta LakeDnsGCPGoHTTPKafkaLinuxPacket CaptureParquetProxiesPub/SubPythonRedshiftRustSnowflakeSpark StreamingSQLSqsUnix
Big Data • Cloud • Information Technology • Software • Analytics
Design and implement backend systems and APIs in Go, contribute full-stack features with React/TypeScript, define observability data models (OpenTelemetry), lead complex cross-team projects, own production services including on-call, mentor engineers, and collaborate with product and design to deliver AI observability features.
Top Skills:
GoOpentelemetryReactTypescript
Retail • Social Media • Software • Analytics
Build and iterate growth experiments, onboarding flows, promotions, and re-engagement campaigns. Design and integrate services/APIs and cloud infrastructure, instrument and analyze product data, apply AI where useful, improve system reliability, and mentor peers to drive activation, engagement, retention, and monetization.
Top Skills:
AWSBigQueryClaudeCodexCursorDevinGraphQLMySQLNode.jsPostgresReactSnowflakeSQLTypescript
Artificial Intelligence • Cloud • Machine Learning
Design, build, test, and deploy secure mission-planning software. Maintain secure CI/CD, containerized deployments, automated testing, and security-scanning workflows. Integrate AI capabilities, investigate vulnerabilities, support remediation, produce technical design documentation, and collaborate with stakeholders and customer leads.
Top Skills:
Agentic AiArtifactoryAutomated TestingCi/CdConfluenceContainersFortifyGitlabJfrog XrayJIRAKubernetesLlm AssistantsOpenshiftOwasp ZapRag (Retrieval-Augmented Generation)Slack
Legal Tech • Software
Build and optimize high-volume web applications using .NET, Node, React and AWS; maintain and improve existing systems; troubleshoot bugs; perform code reviews; mentor junior engineers; participate in on-call rotation; and improve scalability and performance.
Top Skills:
.NetAngularjsAWSC#ElasticsearchGitJavaScriptMs SqlNode.jsReactRedisTypescript
Legal Tech • Software
The Senior Software Development Engineer will develop applications using modern programming languages, provide leadership and mentoring, ensure software quality, and lead software improvement initiatives.
Top Skills:
.NetAWSC#Ms SqlOpensearchRedisTypescript
Fintech • Healthtech • Insurance • Mobile
The Senior Software Engineer will build and ship full-stack features, design scalable systems, integrate AI tools, and maintain high coding standards in a fast-paced startup environment.
Top Skills:
Ai Tools (ClaudeAWSCursor)JavaScriptNext.JsReactTypescript
Healthtech • HR Tech
The role involves overseeing full-stack development, creating APIs, improving microservices, and collaborating with cross-functional teams to enhance mental health care interfaces.
Top Skills:
Ai ToolsJavaPythonReact NativeReactSpringTypescript
Software
The staff software engineer will lead technical design, develop AWS microservices and automation solutions, and mentor team members.
Top Skills:
Api GatewayAWSAws BedrockAws LambdaCloudwatchEventbridgeIamRest ApisSecrets ManagerSnsSqsWorkato
Healthtech • Database
Lead design and implementation of health data products, mentor engineers, own multiple projects, and develop scalable data solutions using modern technologies.
Top Skills:
AWSAzureElasticsearchJavaJavaScriptPythonReactScalaSparkTypescript
New
Track Smarter, Apply Better.
Ditch the spreadsheets. Organize your job search with our freeApplication Tracker.
Use For Free
Healthtech • Database
The Senior Software Engineer will lead development, mentor engineers, and create data solutions using TypeScript, React, and Python. Responsibilities include designing applications, driving innovation, and ensuring high-quality user experiences.
Top Skills:
AWSPythonReactTypescript
Healthtech • Database
Lead design and implementation of products, mentor engineers, drive innovation, and build scalable data solutions using modern tech stack.
Top Skills:
AWSCassandraDatabricksJavaKafkaPythonRedisScalaSparkSQL
Healthtech • Database
As a Senior/Staff Software Engineer, you will design and implement products, guide other engineers, and drive innovation in health data solutions.
Top Skills:
AWSAzureJavaScriptPythonReactSnowflakeSparkTypescript
Big Data • Information Technology • Machine Learning • Sales • Software • Database • Generative AI
Design, implement, and operate scalable, fault-tolerant web crawling and extraction pipelines processing massive web data. Write production Java/Python code, build ETL/ELT pipelines (BigQuery/Snowflake), use Kafka, Kubernetes (GKE/EKS), Terraform, and Airflow, and improve observability, reliability, and collaboration with product and data science teams.
Top Skills:
Apache AirflowApache KafkaAWSBigQueryGCPJavaKubernetes (Gke/Eks)Proxy Management SystemsPythonScrapySnowflakeStarburstTerraformTrinoVertex Ai
Legal Tech • Software
Lead quality efforts across backend services, APIs, and customer-facing apps. Design and implement automated test frameworks, build custom tooling and load testing solutions, improve testing pipeline scalability, mentor engineers, and apply GenAI/LLMs to testing and test-generation challenges.
Top Skills:
Automated Testing FrameworksC#GenaiJavaLlmsLoad Testing ToolsRest
Fintech • Real Estate • Software
As a Staff Software Engineer, you'll design and deliver a core data platform, focusing on architecture, pipeline components, and AI integration. This hands-on role emphasizes creating production code and establishing technical standards within a small team.
Top Skills:
AWSEltETLLlmsRedshift
Healthtech • Software
Build and maintain high-performance Ruby on Rails services on a Rails/AWS/Kubernetes stack. Own end-to-end feature development, optimize DB queries and APIs, support legacy modernization and new product growth, participate in on-call rotation, and drive CI/CD, testing, and architectural improvements.
Top Skills:
AWSCi/CdCircleCICloudwatchEcsEksGitGithub ActionsJenkinsKubernetesLambdaMySQLPostgresRubyRuby On RailsS3Test-Driven Development (Tdd)
Security
Build full-stack features for Google Drive and OAuth surfaces, design and ship LLM-powered agentic workflows for detection, investigation, and remediation, integrate with Google Workspace APIs at scale, partner with product and design, collaborate across teams, and contribute through mentorship, code review, and ownership from design to production.
Top Skills:
Google Drive ApiGoogle Workspace ApisLlmsOauthReactTypescript
Software
Lead design and rewrite of cloud-native core systems. Build scalable back-end services and front-end features, drive architecture and testing discussions, mentor engineers, and improve telemetry, performance, and reliability.
Top Skills:
.Net.Net CoreAWSAzure DevopsC#JavaKubernetesNode.jsOpentelemetryPostgresRuby on RailsReact
Healthtech
Lead refactoring and optimization of scalable data pipelines, design next-generation distributed storage and processing systems, build clean interfaces for diverse data consumers, mentor engineers, and establish engineering standards and processes.
Top Skills:
AWSAzureC#C++Ci/CdDatabricksDockerEtl/EltEvent-DrivenGCPGoIn-Memory ComputingJavaKubernetesPythonRedshiftScalaSnowflakeSparkSQL
Insurance
Design, build, and operate scalable web applications, APIs, services, and AI-enabled workflows. Use AI tools across the development lifecycle, ensure reliability, performance, and observability, contribute to technical decisions, iterate from user feedback, and own production quality and delivery as part of cross-functional squads.
Top Skills:
AWSAzureNode.jsPostgresReactRedisSnowflakeTypescript
Productivity • Software • Conversational AI
Senior Software Engineer at Twilio will design, build, and maintain scalable communication systems, collaborate with cross-functional teams, mentor engineers, and contribute to architecture and delivery. Responsibilities include writing high-quality code, improving performance and reliability, shipping product features, and participating in technical planning within a remote-first, inclusive environment.
Insurance
Lead and coach a software engineering team to design and deliver production-grade reference architectures, sample applications, and reusable implementation patterns. Provide hands-on technical leadership across cloud-native, containerized, and distributed systems; drive architecture and adoption of best practices; partner with platform and infrastructure teams; participate in coding, prototyping, and troubleshooting; manage staffing, prioritization, and delivery planning.
Top Skills:
APIsAWSContainer TechnologiesDistributed SystemsEvent-Driven ArchitecturesGoogle Cloud PlatformJavaKubernetesMessaging PlatformsMicroservicesAzure
Let Your Resume Do The Work
Upload your resume to be matched with jobs you're a great fit for.
Success! We'll use this to further personalize your experience.
Top Companies in Charleston, SC Hiring Senior Software Engineers Roles
See AllPopular Charleston, SC Senior Level Job Searches
Senior Level Jobs in Charleston
Senior Remote Jobs in Charleston
Senior Content Jobs in Charleston
Senior Customer Success Jobs in Charleston
Senior IT Jobs in Charleston
Senior Cyber Security Jobs in Charleston
Senior Tech Support Jobs in Charleston
Senior Data & Analytics Jobs in Charleston
Senior Analysis Reporting Jobs in Charleston
Senior Analytics Jobs in Charleston
Senior Business Intelligence Jobs in Charleston
Senior Data Engineer Jobs in Charleston
Senior Data Science Jobs in Charleston
Senior Machine Learning Jobs in Charleston
Senior Data Management Jobs in Charleston
Senior UX Designer Jobs in Charleston
Senior Software Engineer Jobs in Charleston
Senior Android Developer Jobs in Charleston
Senior C# Jobs in Charleston
Senior C++ Jobs in Charleston
Senior DevOps Jobs in Charleston
Senior Front End Developer Jobs in Charleston
Senior Golang Jobs in Charleston
Senior Hardware Engineer Jobs in Charleston
Senior iOS Developer Jobs in Charleston
Senior Java Developer Jobs in Charleston
Senior Javascript Jobs in Charleston
Senior Linux Jobs in Charleston
Senior Engineering Manager Jobs in Charleston
Senior .NET Developer Jobs in Charleston
Senior PHP Developer Jobs in Charleston
Senior Python Jobs in Charleston
Senior QA Jobs in Charleston
Senior Ruby Jobs in Charleston
Senior Salesforce Developer Jobs in Charleston
Senior Scala Jobs in Charleston
Senior Finance Jobs in Charleston
Senior HR Jobs in Charleston
Senior Legal Jobs in Charleston
Senior Marketing Jobs in Charleston
Senior Operations Jobs in Charleston
Senior Office Manager Jobs in Charleston
Senior Operations Manager Jobs in Charleston
Senior Product Manager Jobs in Charleston
Senior Project Manager Jobs in Charleston
Senior Sales Jobs in Charleston
Senior Account Executive (AE) Jobs in Charleston
Senior Account Manager (AM) Jobs in Charleston
Senior Sales Leadership Jobs in Charleston
Senior Sales Development Representative Jobs in Charleston
Senior Sales Engineer Jobs in Charleston
Senior Sales Operations Jobs in Charleston
All Filters
Total selected ()
No Results
No Results


















_0.png)












