Top Senior Machine Learning Jobs in Charleston, SC

Design, build, and ship AI-powered observability features using LLMs and agentic workflows. Rapidly prototype, iterate with real users, integrate AI into alerting, runbooks, and developer workflows, and ensure solutions are scalable, maintainable, and production-ready while collaborating cross-functionally.

Lead and scale Vibrant's data science, ML, and AI function: set strategy and governance, oversee applied research and production ML (especially NLP), ensure HIPAA-compliant deployments, partner with execs and engineering, recruit and mentor teams, and deliver measurable outcomes for crisis services and enterprise initiatives.

Lead a Machine Learning engineering team owning mission, execution, morale, and code quality. Partner with product to deliver roadmap, remove roadblocks, improve processes, coach and grow engineers, and drive development, deployment, and innovation of ML models for recommender, search, and matching systems.

Design, develop, and deploy state-of-the-art deep learning models for multimodal and satellite imagery; own ML architecture, infrastructure, model registries, and inference services; mentor the team, translate product vision into technical roadmaps, and integrate research into production-ready, scalable geospatial AI systems.

Lead end-to-end architecture and delivery of production ML and generative AI platforms on Azure and Microsoft Fabric. Define MLOps, CI/CD, governance, observability, retrieval/LLM patterns, security, cost controls, and operational handoff. Work with data scientists and engineers to translate requirements, defend tradeoffs, and ensure systems run unattended in production.

Design and improve ML training frameworks, modularize experiments, adapt fire-hazard detection algorithms for varied electrical environments, build scalable pipelines for high-frequency sensor data, and develop dashboards and tooling to monitor model performance and drift while collaborating across product, data science, and fire safety teams.

Build and re-architect Shipt's LLM-native search stack including retrieval and ranking systems. Design multi-task and multi-objective models, integrate personalization signals, develop hybrid dense/sparse retrieval, and apply generative retrieval and query expansion. Analyze search data, report findings to leadership, and partner with senior scientists and ML engineers to improve relevance, revenue trade-offs, and operational metrics.

Lead a team of data scientists developing ML-driven products, managing infrastructure, training models, and ensuring production quality while collaborating with senior leadership.

The AI/ML Engineering Manager leads a team of ML engineers and architects, managing hiring, performance, and customer engagements while providing technical guidance in ML operations and architecture.

Design, build and deploy production AI/ML solutions from complex, distributed farm data. Engineer features, select models, run experiments, move models to scalable real-time production, monitor and observe AI systems, evaluate emerging AI technologies, and collaborate with product, engineering and domain teams. Contribute to user-facing features with React/TypeScript as needed.

Design, build, and deploy production-grade AI/ML solutions that convert complex, distributed farm data into actionable intelligence. Engineer features, select models, run experiments, and move models to scalable, real-time production. Integrate, fine-tune, monitor, and observe models on cloud infrastructure (AWS, Databricks). Partner with product, engineering and domain teams and contribute to user-facing experiences when needed.

Design, evaluate, and productionize generative AI/ML solutions (RAG, agents, embeddings, retrieval). Build evaluation frameworks for hallucination detection, benchmark LLMs, optimize prompts/models, create datasets, fine-tune models, and collaborate to deploy and monitor enterprise-scale GenAI systems.

Lead development of scalable AI/ML capabilities for Mail Intelligence: build LLM- and ML-based personalization, data pipelines, tools, and observability. Mentor engineers, collaborate cross-functionally, run A/B tests, implement feedback loops, and balance cost/quality/speed tradeoffs to deliver production-grade solutions.

Design, build, and deploy scalable distributed deep learning pipelines and infrastructure. Optimize hardware utilization, profile and benchmark training, manage large datasets, and enable reproducible ML workflows in cloud environments. Collaborate with ML scientists and engineers to align pipelines with research goals and drive performance, reliability, and operational best practices for large-scale model development.

The role involves leading ML strategy, architecting systems, designing algorithms, collaborating with teams, and mentoring engineers in AI for enterprise analytics.

The role involves applying AI/ML techniques to develop model systems for healthcare, collaborating across teams, and conducting R&D.

The Senior Machine Learning Engineer will design, train, and deploy ML models for optimizing revenue in advertising, taking ownership of product development and leading the ML discipline.

Lead the development of device intelligence and fingerprinting systems by designing backend services, collaborating on integrations, and applying advanced machine learning algorithms to enhance security and combat fraud.

Lead and grow the AI/ML Engineering team, manage core AI/ML platform development, ensure production-grade service operational excellence, and develop product strategies.

Build and productionize large-scale ML models and pipelines for query understanding and personalization. Work on autocomplete, query tagging/NER, query expansion, intent modeling, and LLM-powered natural-language search. Collaborate cross-functionally to design, deploy, and monitor batch and real-time systems, leveraging modern ML infrastructure and tooling to improve search relevance across Airbnb products.

Build and productionize ML models and data infrastructure to analyze millions of chaos engineering experiments, detect and explain failures, recommend automated remediation, and integrate AI-driven failure analysis into Gremlin's product using techniques like causal inference, graph ML, time-series modeling, and reinforcement learning.

Lead architecture and technical strategy for Lyra's ML and generative AI platform. Design training, fine-tuning, and low-latency inference infrastructure (RAG, vector DBs), set ML/AI SDLC standards (dataset lineage, CI/CD, evaluation, monitoring), partner with cross-functional clinical and product teams, mentor senior engineers, deliver prototypes and critical code, and ensure secure, reliable production ML systems.

The Senior Manager, Data Science/ML will lead a team to enhance product innovation through data science, focusing on ML and experimentation frameworks that boost customer engagement. Responsibilities include defining product strategy, building ML models, and collaborating with cross-functional teams to shape product roadmaps.

The Senior ML Engineer will automate component placement on PCBs, working on R&D and production using ML and optimization techniques.

As a Senior/Staff ML Systems Engineer at Quilter, you'll design and maintain ML infrastructure for automated PCB component placement, manage data pipelines, and lead systems design reviews while ensuring project efficiency and reliability within a fully distributed team.