Top Remote Machine Learning Jobs in Indianapolis, IN

Lead and manage the underwriting and credit risk model validation team, perform hands-on independent validations of complex ML models, assess data integrity and performance, identify and remediate model weaknesses, partner on MRM framework improvements, and coordinate with audit, compliance, and controls to meet regulatory standards.

Lead long-term technical strategy and execution across multiple teams, architecting and evolving foundational frontend/backend systems and platforms at massive scale. Drive AI/ML adoption, solve ambiguous, high-impact problems, remain hands-on in critical system design and implementation, and align senior leaders on roadmaps and engineering standards.

Lead the development of machine learning systems for Cedar Pay's Personalization Engine, manage ML engineers, and ensure ML model effectiveness.

Own the strategy, roadmap, adoption, retention, and monetization of Givebutter Plus CRM, marketing, and reporting products. Lead customer discovery, quantitative and qualitative analysis, product definition, and cross-functional delivery with Design and Engineering. Align stakeholders, define success criteria, incorporate AI, run experiments, and connect product initiatives to business outcomes including SaaS growth and revenue retention.

The Staff Machine Learning Engineer will lead ML initiatives, develop ML systems, collaborate with cross-functional teams, and mentor junior engineers to optimize healthcare intake workflows using advanced machine learning techniques.

Lead and transform the Fraud Intelligence Team by designing scalable operating models, QA and measurement frameworks, and talent programs. Drive labeling quality, operational metrics, and fraud prevention impact; convert frontline fraud observations into insights for Product, R&D, Analytics, and GTM; leverage AI, automation, and tooling; and serve as a cross-functional fraud subject-matter expert while developing early-career talent and measurable business outcomes.

Integrate operational data into enterprise data warehouses; design, optimize, and support SSIS ETL pipelines; develop SSRS and Power BI reporting solutions and reusable data models; deliver data migrations and self-service extracts. Design production AI/ML solutions using Python, OCR, AWS Bedrock, and Claude, including multi-agent LLM implementations. Partner with stakeholders, lead code reviews, mentor developers, and support production BI deployments.

Lead the design and implementation of critical Safety AI initiatives, focusing on real-time perception systems for edge devices and optimizing models for production deployment in safety-critical environments.

Lead ecosystem-level data science and econometric analyses across Xbox, Game Pass, Console, PC, and Store experiences. Evaluate growth, engagement, monetization, experiments, incrementality, and investment ROI using statistical and causal inference methods. Build reusable analytical products and self-service capabilities, influence executive decisions, and mentor team members.

Develops, configures, tests, and supports AI solutions, workflows, integrations, and model-enabled applications. Creates technical instructions and documentation, troubleshoots and optimizes AI systems, coordinates technical tasks, and collaborates with architects, delivery leaders, project teams, and stakeholders. Requires a college degree or equivalent, three years of related experience, technical communication skills, and the ability to travel and participate in on-call availability.

Evaluates and compares AI-generated responses in English and French for accuracy, relevance, reasoning, clarity, safety, cultural appropriateness, and overall usefulness. Applies detailed annotation guidelines consistently across varied content types, documents evidence-based decisions, meets daily productivity expectations, and participates in training, calibration, qualification, and quality reviews.

Own the full machine learning lifecycle for search ranking and retrieval, including model training, deployment, serving, feature pipelines, evaluation frameworks, hybrid lexical-vector retrieval, large-scale embedding inference, query understanding, and permissions-aware multi-tenant search. Collaborate with infrastructure, AI, and backend teams to improve search relevance across ClickUp’s platform.

Research agentic AI use cases for customer-facing fintech features and develop working prototypes. Design, build, and productionize advanced models while collaborating with Product, Engineering, Analytics, and Applied Science teams. The intern will contribute to customer experience, operational efficiency, and business outcomes in an eight-week, full-time program based in New York City.

Define technical vision and architecture for agentic, multi-agent systems that improve autonomous-driving event triage and evaluation. Lead development of scalable frameworks supporting dynamic reasoning, planning, tool use, self-reflection, and orchestration. Identify applications across the Waymo Driver evaluation lifecycle, establish roadmaps, collaborate across teams, and mentor engineers. The role requires extensive software engineering and AI/ML expertise, technical leadership, and experience building complex production systems.

Leads the enterprise analytics organization, managing Analytics Engineers, Data Analysts, and BI Developers. Defines analytics strategy; delivers executive dashboards, KPI scorecards, operational reporting, semantic models, and self-service BI. Establishes data governance and metric standards, ensures data quality, partners with Engineering, Product, Finance, Operations, and executives, and translates business questions into actionable analytical solutions. Mentors analytics talent and drives prioritization, adoption, and measurable business outcomes.

Senior backend engineer responsible for setting technical direction, designing scalable distributed systems, building customer-facing web applications, mentoring engineers, and applying machine learning to large-scale healthcare data. The role requires Java, Scala, or Rust expertise, cloud systems experience, technical design leadership, cross-functional collaboration, and adoption of agentic engineering practices.

Embeds with strategic customers to understand security and risk workflows, then builds AI-native solutions, integrations, data pipelines, and production software. Translates security ratings into financial risk metrics, architects solutions across AWS, Azure, and GCP, prototypes rapidly, and supports deployment. The role bridges customers, Product, Engineering, Sales Engineering, and Customer Success while owning technical relationships and traveling onsite for workshops and go-live support.

Leads Alkami’s enterprise and technology risk management program, including risk assessments, control evaluations, mitigation, monitoring, reporting, and escalation. Owns AI, machine learning, and generative AI governance, translating regulatory and risk expectations into practical policies, controls, and review processes. Partners with cross-functional risk owners and supports compliance initiatives involving business continuity, disaster recovery, regulatory management, and incidents. Reports to the Chief Compliance Officer in a fully remote role.

Lead technical strategy and architecture for Azure Storage geo-replication, data protection, failover orchestration, and business continuity. Drive cross-team delivery, operational excellence, telemetry, automation, AI-assisted operations, and represent the team in executive and customer engagements.

Provides product and technology legal counseling throughout the product lifecycle while operating Horizon3’s global privacy program. Advises Product, Engineering, Security, Compliance, and GTM teams on privacy laws, AI regulation, data flows, DPAs, cross-border transfers, privacy-by-design, incidents, audits, and customer diligence. Drafts playbooks, policies, notices, and contractual terms; supports enterprise negotiations; and delivers practical, risk-based guidance in a fast-moving cybersecurity environment.

Owns pricing and revenue optimization across a nationwide furnished-apartment portfolio. Develops dynamic pricing strategies, enhances machine learning models, analyzes elasticity and occupancy forecasts, builds performance dashboards, integrates external market data, and evaluates channel mix and ROAS tradeoffs. Partners with Marketing, Product, Engineering, and Operations while presenting pricing and investment recommendations to senior leadership.

Leads large-scale AI transformation programs for Cresta’s strategic enterprise customers. Serves as executive sponsor and trusted advisor to C-suite stakeholders, manages matrixed implementation and engineering teams, oversees complex deployments, standardizes delivery governance, and drives measurable customer value, adoption, expansion, and advocacy. Partners with Sales, Customer Success, Product, and Engineering while connecting technical outcomes to business ROI.

Adjudicate automated vessel detections humans cant resolve: identify dark/spoofed/low-confidence contacts, investigate AIS/GNSS manipulation and ownership, produce sourced identification records, and supply labeled ground truth to improve detection models.

Lead strategy and execution for enterprise and mid-market GTM across multi-unit restaurant brands. Drive C-suite engagements, modernize sales motions, scale AI-powered forecasting, partner with Product/Engineering, and represent Toast in industry forums to win large, complex contracts.

Evaluate AI model outputs on data science, statistics, machine learning, experimentation, and quantitative problems. Develop expert prompts, datasets, and reference solutions; identify statistical and methodological errors; and provide structured feedback to improve model performance. The role requires Python, machine learning, statistics, data analysis, experimentation, Pandas, and data modeling skills.