Top Senior Machine Learning Jobs in Des Moines, IA

28 Days AgoSaved
Remote
Des Moines, IA
150K-215K Annually
Senior level
150K-215K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
Design and lead the technical strategy for search across Vannevar’s products. Build and improve full-text, vector, and LLM-powered retrieval systems, optimizing latency, relevance, index quality, freshness, and performance. Collaborate with ML, product, design, and mission strategy teams to translate user needs into search innovations. Apply expertise in information retrieval, NLP, machine learning, indexing, ranking, query parsing, tokenization, vector search, and evaluation frameworks.
Top Skills: ElasticsearchFull-Text SearchInformation RetrievalLlmsMachine LearningNlpOpensearchVector Databases
Reposted 15 Minutes AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Big Data • Cloud • Information Technology
Design and deliver secure, high-performance microservices and APIs. Develop backend services in Java and Python, integrate ML components, build front-end service layers, deploy containerized applications to cloud platforms, and collaborate in Agile teams to ensure scalable, test-driven solutions.
Top Skills: AngularApi GatewaysArtifactoryAtlassian JiraAWSDockerFlaskGitGoogle Cloud PlatformJavaJSONKubernetesLinux Shell ScriptingMachine LearningAzureMySQLOraclePostgresPythonRallyReactRestSpring BootSQL ServerTeam Foundation ServerVersion One
35 Minutes AgoSaved
In-Office or Remote
Des Moines, IA
110K-187K Annually
Senior level
110K-187K Annually
Senior level
Fintech • Insurance
Owns the backlog, sprint cadence, releases, and production health of enterprise AI products. Translates product strategy into requirements, user stories, work packages, and sprint goals while coordinating engineers, data scientists, business partners, and dependent teams. Leads Scrum ceremonies, PI planning, testing, release communications, and uptime monitoring. Applies AI tooling to improve delivery and uses technical fluency to prototype, review pull requests, and support responsible AI implementation.
Top Skills: AgileAIAi/Ml DevopsComputer VisionDatabricksDeep LearningGenerative AiJIRAMachine LearningExcelMicrosoft PowerpointMiroOcrOptimizationRobotic Process AutomationScrumSdlc
Reposted An Hour AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Professional Services • Software
Lead and grow a team of Conversation Designers to build and scale conversational AI experiences. Partner with Product, Engineering, Analytics, and ML teams to drive strategy, tooling, evaluation, and quality practices. Recruit and remove roadblocks, own strategic initiatives, and remain hands-on in designing, testing, and improving AI-driven conversational products.
Top Skills: A/B TestingAi ToolsEvaluation FrameworksLlmsMachine Learning
2 Hours AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Legal Tech
Leads strategy, roadmap, execution, commercialization, and customer outcomes for a major enterprise software product area. Conducts market and customer discovery, prioritizes opportunities, partners with engineering and design, establishes outcome-based metrics, and supports sales enablement. Builds and coaches the product management team, manages executive and customer relationships, and helps transition the company from services-led to product-led operations. The role emphasizes legal technology, eDiscovery, AI-enabled workflows, enterprise data, and regulated-industry requirements.
Top Skills: AIB2B SaasEdiscovery TechnologyEnterprise Data PlatformsLegal TechnologyMachine Learning
2 Hours AgoSaved
Remote
Des Moines, IA
150K-215K Annually
Senior level
150K-215K Annually
Senior level
Other
Lead architecture and technical strategy for a remote engineering organization building a React, Node.js, PostgreSQL, and AWS platform. Mentor engineers, establish engineering standards, drive JavaScript-to-TypeScript migration, design ETL and AI/LLM integration systems, resolve technical debt, and oversee technical design reviews, production support, incident response, hiring, and delivery. Partner with product, clinical, and business stakeholders to build scalable, reliable software.
Top Skills: AIAmazon EcsAmazon RdsAmazon S3AWSAws LambdaData PipelinesDistributed SystemsEtl PipelinesEvent-Driven ArchitecturesExpressJavaScriptLlmMachine LearningMessage QueuesNode.jsPostgresReactStreaming PipelinesTypescript
9 Hours AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Fintech • Payments • Financial Services
Develop machine learning, AI, statistical, and predictive models using Snowflake and other data sources. Perform data extraction, cleansing, feature engineering, experimentation, visualization, and quality analysis. Partner with business and technical teams to deliver data products, conversational analytics, and actionable recommendations. Lead discovery sessions, communicate insights to nontechnical audiences, mentor analysts, and support enterprise data science projects.
Top Skills: Artificial IntelligenceData VisualizationMachine LearningNatural Language ProcessingPythonRSnowflakeSQL
12 Hours AgoSaved
Remote
Des Moines, IA
165K-185K Annually
Senior level
165K-185K Annually
Senior level
Artificial Intelligence • Insurance • Software • Automation
Own technical delivery and account health for insurer software deployments. Responsibilities include discovery, solution design, integrations, API and payload review, QA testing, defect documentation, workflow mapping, SQL-based production monitoring, incident management, and technical communication with carrier accounts and engineering teams.
Top Skills: APIsJSONMachine LearningSQL
Reposted 14 Hours AgoSaved
Remote or Hybrid
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
Lead hands-on engineering for an AI-powered email application across backend, mobile, and desktop platforms. Design reliable AI workflows involving orchestration, state, tool use, retries, fallbacks, and failure handling. Define APIs and abstractions, make architecture and scalability decisions, improve observability and reliability, and lead a small team of senior engineers through technical reviews, mentorship, and production delivery.
Top Skills: AIAPIsBackend ServicesDesktop ApplicationsLarge Language ModelsMachine LearningMobile ApplicationsMonitoringObservability
Reposted YesterdaySaved
Remote
Des Moines, IA
184K-221K Annually
Senior level
184K-221K Annually
Senior level
Fintech • Software
Build and scale accounting software synchronization solutions connecting BILL’s payment network with third-party accounting platforms. Lead end-to-end software design and delivery, develop scalable AWS microservices, improve platform performance, guide testing and CI/CD practices, resolve customer problems, mentor engineers, and use generative AI to accelerate development.
Top Skills: AngularAWSCi/CdDatadogGenerative AiJavaLaunchdarklyLlmsMachine LearningMicroservicesMixpanelNoSQLReactRecommendation EnginesSplunkSQL
29 Days AgoSaved
Remote
Des Moines, IA
300K-400K Annually
Senior level
300K-400K Annually
Senior level
Artificial Intelligence • Cloud • Software • Infrastructure as a Service (IaaS)
Lead Runpod’s Americas sales organization and revenue number across new business, expansion, and renewals. Manage and coach Account Executives and Account Managers, oversee forecasting and pipeline, lead complex enterprise deals and contract negotiations, build regional go-to-market strategy and sales playbooks, and convert product-led demand into revenue. Partner with Marketing, Product, Legal, and Finance while improving sales efficiency through AI and developing a remote-first team.
Top Skills: AICloud ComputingCRMGpu CloudMachine LearningMlopsSlack
Reposted YesterdaySaved
In-Office or Remote
Des Moines, IA
102K-261K Annually
Senior level
102K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Designs, builds, scales, and operates distributed CI/CD services supporting millions of builds, tests, and releases. Develops code for Azure-based infrastructure spanning virtual machines, containers, and custom lab environments. Responsibilities include requirements analysis, architecture and design documentation, estimation, debugging, optimization, operational playbooks, on-call incident response, monitoring, reliability improvements, and mentoring engineers.
Top Skills: AzureCC#C++Ci/CdContainersDistributed SystemsJavaJavaScriptMachine LearningMonitoringObservabilityPythonStatic AnalysisVirtual Machines
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YesterdaySaved
Remote
Des Moines, IA
108K-143K Annually
Senior level
108K-143K Annually
Senior level
Big Data • Cloud • Information Technology
Designs and implements enterprise cloud and AI solutions for unstructured data workloads. Responsibilities include building ingestion pipelines, API integrations, document extraction and HITL workflows, tuning machine learning models, benchmarking performance, and ensuring security, availability, disaster recovery, and data isolation. The role also supports customer developers, leads technical proofs of concept, mentors engineering teams, develops reusable blueprints, and provides feedback to product engineering.
Top Skills: AzureBashDocument AiGCPGraphQLIcrMachine LearningMongoDBOcrPostgresPythonRestServerless ArchitectureSQL
Reposted YesterdaySaved
Remote
Des Moines, IA
Senior level
Senior level
Healthtech
Leads the full lifecycle of clinical NGS diagnostic algorithms for oncology and liquid biopsy applications. Responsibilities include algorithm design, analytical validation, design control, regulatory readiness, variant calling, QC metric development, probabilistic modeling, machine learning, and validation pipeline automation. The role serves as technical authority for algorithm changes, supports regulatory submissions, and develops solutions for low-input, fragmented, and ultra-low-frequency genomic variants.
Top Skills: Analytical Validation AutomationBayesian InferenceDna SequencingMachine LearningNext-Generation Sequencing (Ngs)PythonRRna SequencingUnique Molecular Identifiers (Umis)Workflow Orchestration
YesterdaySaved
Remote
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Information Technology • Software
Serves as a permitting and plan review domain expert for engineering, product, design, data, and go-to-market teams. Reviews permit applications, plan sets, submittals, and AI outputs; interprets building codes; identifies missing or noncompliant information; defines approval and revision criteria; labels examples for ML systems; synthesizes jurisdictional requirements; and develops rubrics, checklists, documentation, and benchmarks. Requires approximately 5+ years of hands-on permitting or plan review experience and fluency in applicable building codes.
Top Skills: Artificial IntelligenceMachine Learning
YesterdaySaved
In-Office or Remote
Des Moines, IA
139K-189K Annually
Senior level
139K-189K Annually
Senior level
Insurance • Software
Leads the Product Acquisition engineering team and drives technology strategy, architecture, software delivery, DevOps maturity, platform adoption, vendor management, and operational excellence. Partners with product managers on roadmaps and business outcomes, ensures engineering standards and production support, and coaches, recruits, and develops engineers and consultants. Requires strong software development, product operating model, project management, stakeholder communication, and technical leadership experience.
Top Skills: Agile/ScrumArtificial IntelligenceAutomationAWSCloud Data PlatformsCloud-Native DevelopmentDevOpsEnterprise IntegrationJavaMachine LearningReactSalesforce
YesterdaySaved
Remote
Des Moines, IA
Senior level
Senior level
Financial Services
Leads customer and marketing analytics strategy, managing a small analytics team and partnering with executives to improve acquisition, retention, engagement, conversion, and customer experience. Develops KPIs, scorecards, journey reporting, cohort analyses, campaign measurement, segmentation, and A/B testing programs. Oversees scalable analytics frameworks, data quality, governance, architecture, and integration across customer touchpoints. Applies advanced analytics and predictive modeling to deliver actionable insights and presents recommendations to senior leadership and board-level audiences.
Top Skills: A/B TestingCrm SystemsData MiningData VisualizationData WarehousingMachine LearningPredictive ModelingStatistical Analysis
YesterdaySaved
Remote
Des Moines, IA
119K-198K Annually
Senior level
119K-198K Annually
Senior level
Energy • Manufacturing • Solar • Renewable Energy
Own the vision, strategy, roadmap, business case, licensing, lifecycle policy, deployment models, and go-to-market strategy for GridBeats Device Management. Lead customer discovery, product requirements, release planning, cross-functional delivery, sales enablement, and KPI tracking. Partner with utilities, engineering, commercial, marketing, and global sales teams to deliver secure device-management software for grid operators and industrial customers.
Top Skills: AgileArtificial IntelligenceCloudContainersDnp3Hybrid DeploymentIec 61850Iec 62351IotMachine LearningMicroservicesModbusNerc CipOn-Premises DeploymentSaaSScada
YesterdaySaved
Remote
Des Moines, IA
292K-344K Annually
Senior level
292K-344K Annually
Senior level
Events • Music • Sports
Lead the development and production deployment of applied machine learning and LLM solutions across product, marketing, and operations. Own ranking, recommendation, filtering, personalization, experimentation, and model evaluation systems. Partner with business and technical teams to identify valuable use cases, establish modeling best practices, and ensure reliable production deployment. Manage and mentor applied ML practitioners while maintaining technical rigor, business alignment, and measurable customer and revenue impact.
Top Skills: EmbeddingsFine-TuningGradient BoostingLarge Language Models (Llms)Learning-To-RankMachine LearningMachine Learning Operations (Mlops)Neural NetworksPersonalizationPrompt EngineeringRecommendation SystemsRetrieval-Augmented Generation (Rag)
29 Days AgoSaved
Easy Apply
Remote or Hybrid
Des Moines, IA
Easy Apply
128K-240K Annually
Senior level
128K-240K Annually
Senior level
Fintech • Mobile • Software • Financial Services
Develops and validates machine learning and statistical models for anti-money laundering, transaction monitoring, customer screening, and risk rating. The role evaluates AML data quality, integrates vendor solutions, maintains governance and regulatory documentation, leads model lifecycle quality control, and reports performance through management dashboards. It also supports AML risk assessments, audits, regulatory examinations, and cross-functional stakeholder coordination.
Top Skills: Cloud ComputingDatadogDistributed ComputingDockerKubernetesLexisnexisMachine LearningMonte CarloPythonSnowflakeSQLStatistical ModelingTableauTerraformTraditional DatabasesVerafin
YesterdaySaved
Remote
Des Moines, IA
130K-190K Annually
Senior level
130K-190K Annually
Senior level
Information Technology • Software • Analytics
Lead the design, development, deployment, and operation of production AI and ML systems. Build high-throughput Python services and Databricks pipelines, support traditional ML and LLM applications, establish testing and deployment standards, and develop monitoring for quality, reliability, latency, throughput, and cost. Partner with product, research, and responsible AI teams on governance and release criteria. Provide architectural leadership, conduct code reviews, mentor engineers, and resolve complex technical dependencies.
Top Skills: AWSAzureCi/CdDatabricksLarge Language ModelsLlm Orchestration FrameworksMachine LearningNlpPythonRetrieval-Augmented GenerationSemantic SearchSpeaker DiarizationSpeech-To-TextSQL
YesterdaySaved
Remote
Des Moines, IA
Senior level
Senior level
AdTech
Build and operationalize machine learning models for large-scale advertising optimization. Responsibilities include designing high-volume services, developing data solutions, training and evaluating models, improving calibration and guardrails, creating offline and online evaluation workflows, and monitoring production systems. The role requires collaboration with product and engineering teams, ownership of reliability and performance, participation in on-call rotations, and deploying scalable, cost-effective ML solutions.
Top Skills: AirflowAutogluonBigQueryDatabricksExperimentation FrameworksGCPKedroMachine LearningMulti-Armed BanditsPolarsProduction Model MonitoringPythonPyTorchQ-LearningReal-Time Data PipelinesReinforcement LearningSQLSqlmesh
2 Days AgoSaved
Remote
Des Moines, IA
128K-173K Annually
Senior level
128K-173K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Leads parallel customer AI/ML solution design engagements from discovery through proposal. Architects enterprise solutions involving predictive analytics, NLP, computer vision, and generative AI; provides cost-benefit and TCO analysis; identifies risks and dependencies; and collaborates with Agile, system architecture, and DevSecOps teams to deploy governed, explainable, and monitored AI/ML systems.
Top Skills: Artificial IntelligenceAws SagemakerAzure MlCi/CdComputer VisionData EngineeringDevsecopsFeature PipelinesGenerative AiGoogle Vertex AiMachine LearningNlpPyTorchScikit-LearnTensorFlow
11 Days AgoSaved
In-Office
Des Moines, IA
118K-222K Annually
Senior level
118K-222K Annually
Senior level
Insurance
Leads software engineering and data technology teams, coaching them on Lean, Agile, DevSecOps, DataOps, MLOps, automation, security, data quality, and observability. Drives engineering maturity, continuous improvement, team formation, staffing, innovation, and delivery outcomes. Manages at least five technology professionals, including performance, hiring, development, compensation, and corrective actions. Partners with governance, architecture, analytics, and business stakeholders to deliver secure, trusted enterprise data platforms and solutions.
Top Skills: AgileAnalyticsArtificial IntelligenceAWSCloud Data PlatformsData GovernanceData ObservabilityData PipelinesDataopsDevsecopsLeanMachine LearningMlops
2 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Healthtech • Software • Analytics
Leads and builds the mid-market business development function, owning territory strategy and the full sales cycle for pharma and biotech accounts. Develops and coaches a high-performing BD team, drives pipeline and new-logo acquisition, closes multi-year SaaS deals, and partners with marketing, strategy, product, and commercial operations. Represents the company at industry events and contributes to commercial frameworks, forecasting, segmentation, and coverage models.
Top Skills: Artificial IntelligenceMachine LearningRisk-Based Monitoring (Rbm)Risk-Based Quality Management (Rbqm)SaaSSalesforce
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