Top Senior Machine Learning Jobs in Des Moines, IA

3 Hours AgoSaved
Remote
Des Moines, IA
48K-168K Annually
Senior level
48K-168K Annually
Senior level
Agency • Information Technology
Lead development of scalable AI/ML capabilities for Mail Intelligence: build LLM- and ML-based personalization, data pipelines, tools, and observability. Mentor engineers, collaborate cross-functionally, run A/B tests, implement feedback loops, and balance cost/quality/speed tradeoffs to deliver production-grade solutions.
Top Skills: Agent FrameworksAirflowC++Ci/Cd For MlClaudeCopilotCursorFeature StoresFine-TuningGoogle Cloud PlatformGpu OptimizationsHadoopJavaLlmopsLlmsMlflowPrompt EngineeringPythonPyTorchRagScikit-LearnSparkTensorFlowVector Databases
8 Hours AgoSaved
Remote
Des Moines, IA
120K-304K Annually
Senior level
120K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Build and maintain a capacity management portal and observability features for ML training and inference. Partner with researchers and PMs to turn requirements into intuitive UIs, integrate backend APIs across schedulers and training frameworks, develop internal tooling, and drive architectural improvements and best practices to improve efficiency and model quality visibility.
Top Skills: CC#C++CSSGenerative Ai ToolsHTMLJavaJavaScriptPythonReactTypescriptVisual StudioVisual Studio Code
23 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Industrial • Manufacturing
Lead manufacturing process improvements for precision optical production: analyze data, reduce cycle time and costs, design/qualify tooling and automation, apply Lean/Six Sigma and AI-enabled analytics, maintain process documentation, partner cross-functionally, drive CAPEX and continuous improvement projects, and train production staff.
Top Skills: Ai-Enabled AnalyticsAutomationData AcquisitionDoeErpFmeaMachine LearningMachine VisionMS OfficeMrpOeePfmeaRoboticsSpc
23 Days AgoSaved
Remote or Hybrid
Des Moines, IA
160K-185K Annually
Senior level
160K-185K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
Serve as the technical lead in pre-sales for state, local, and education customers: run discovery, design POCs and workshops, deliver demos, map needs to Socure solutions, advise on fraud/risk/compliance, influence product, and mentor junior consultants.
Top Skills: APIsCloud-Based PlatformsData ScienceMachine LearningRdbms
Reposted 21 Hours AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Machine Learning • Software
Lead and grow the AI/ML Engineering team, manage core AI/ML platform development, ensure production-grade service operational excellence, and develop product strategies.
Top Skills: AIJavaMlPythonRustScala
Reposted 23 Days AgoSaved
Remote
Des Moines, IA
134K-174K Annually
Senior level
134K-174K Annually
Senior level
Cloud • Social Impact • Software
The Engineering Manager will lead teams in developing and managing Blackbaud's Data & AI platform, focusing on scalability, security, and cost-efficiency.
Top Skills: Data PipelinesFeature ServicesLakehouseMachine Learning
Reposted 23 Days AgoSaved
Remote
Des Moines, IA
185K-215K Annually
Senior level
185K-215K Annually
Senior level
Software
The role involves developing and integrating AI features into Cribl's products, collaborating with teams, and maintaining operational efficiency.
Top Skills: AIGoJavaJavaScriptMachine LearningNode.jsReactTypescript
YesterdaySaved
Remote
Des Moines, IA
235K-250K Annually
Senior level
235K-250K Annually
Senior level
Fintech
Own end-to-end ML lifecycle for pricing and underwriting: improve model accuracy and coverage, reduce infrastructure cost, deploy and monitor production models on AWS, run experiments/backtests, and collaborate with domain experts to inform model improvements and product APIs.
Top Skills: AWSCi/CdEnsemble EstimatorsFoundation ModelsGradient-Boosted ModelsIacLlmsMlflowPythonScikit-LearnSQL
YesterdaySaved
Remote
Des Moines, IA
180K-220K Annually
Senior level
180K-220K Annually
Senior level
Healthtech
Lead MLOps for production ML lifecycle: deploy and serve models, build scalable reproducible pipelines for large protein-design workloads, implement CI/CD and observability, optimize GPU/accelerated compute, and enable self-service tooling for researchers.
Top Skills: AirflowAlphafoldAzureAzure MlBashBoltzgenChaiCi/CdCudaDagsterDockerGpuGrafanaInfrastructure As Code (Iac)KubeflowKubernetesLangfuseMlflowNextflowOpentelemetryPrefectPrometheusProteinmpnnPythonRfdiffusionWeights & Biases
YesterdaySaved
Remote
Des Moines, IA
118K-171K Annually
Senior level
118K-171K Annually
Senior level
Beauty • Cloud • Fintech • Marketing Tech • Payments • Productivity • Software
Design, build, and productionize ML and AI systems (LLMs, embeddings, recommendations, forecasting). Develop end-to-end ML workflows, scalable data pipelines, semantic models, and CI/CD for ML. Collaborate with product and engineering, mentor engineers, and influence platform architecture and standards.
Top Skills: Ci/CdDatabricksEmbeddingsForecasting ModelsLlmsMl FrameworksMlopsPythonRecommendation SystemsSemantic LayerSnowflakeSnowflake CortexSQL
Reposted 24 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Logistics • Software
Lead development of digital twin and simulation models for warehouse operations, deploy AI-driven decision systems, build forecasting and optimization models, validate experiments linking operational metrics to financial impact, and partner with engineers, operations, and external AI/academic partners to scale innovations across fulfillment networks.
Top Skills: Agentic AiAnylogicContinuous SimulationDigital TwinDiscrete-Event SimulationFlexsimLlmsMachine LearningOmsOptimizationPythonRSimioSQLWms
Reposted 24 Days AgoSaved
Remote
Des Moines, IA
150K-165K Annually
Senior level
150K-165K Annually
Senior level
Legal Tech • Software
Lead end-to-end delivery of LOIS by owning the master program plan, coordinating cross-functional teams (engineering, product, design, ML, data, SRE, operations), resolving blockers and dependencies, establishing lightweight delivery infrastructure and tooling, partnering on release planning, and maintaining transparent status, risks, and accountability to deliver complex features to customers.
Top Skills: APIsData PipelinesData ScienceJIRALinearLlmMachine Learning
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Reposted 24 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Fintech • Financial Services
Lead fraud detection and mitigation for a conversational BNPL product. Define fraud typologies, own repayment and chargeback analytics, manage fraud KPIs, design operational policies, collaborate on ML models and decisioning workflows, and coordinate SARs and compliance reporting.
Top Skills: Bi Visualization ToolsBlockchainMachine LearningProvenirPythonRSQLStablecoinsTaktileWhatsapp
Reposted 24 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Fintech • Financial Services
Lead credit analytics for the Send Now Pay Later product: build and maintain credit policies, pricing models, vintage and NPV analyses, executive reporting, model integration and testing, and explore alternative data to optimize approval rates and portfolio health.
Top Skills: DbtMachine LearningPythonRSQL
Reposted 24 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Fintech • Financial Services
Lead fraud detection and mitigation for a conversational Send Now Pay Later product: define first-party fraud typologies, own repayment and chargeback analytics, manage fraud KPIs, design operational policies, integrate ML and decisioning tools (Taktile), and coordinate SARs and compliance reporting.
Top Skills: Bi Visualization ToolsBlockchainMachine LearningProvenirPythonRSQLStablecoinsTaktileWhatsapp
Reposted 24 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Fintech • Financial Services
Lead fraud detection and mitigation for a conversational BNPL product: define fraud typologies, analyze repayment/chargeback trends, own fraud KPIs, design policies, collaborate on ML models and decisioning workflows, and coordinate SARs with Compliance.
Top Skills: AIBi Visualization ToolsBlockchainMachine LearningProvenirPythonRSQLStablecoinsTaktileWhatsapp
Reposted 24 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Fintech • Financial Services
Lead credit analytics for the Send Now Pay Later product: build and optimize valuation, vintage and NPV models; manage credit policies, portfolio monitoring, and NPL reporting; integrate and test scoring models with engineering/data science; and research alternative data to improve predictive performance.
Top Skills: AIBlockchainDbtMachine LearningPythonRSQLStablecoinsWhatsapp
Reposted 24 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Fintech • Financial Services
Lead fraud risk for a conversational lending product (SNPL): define first-party fraud typologies, analyze repayment and chargeback trends, own fraud KPIs, design automated/manual blocking policies, coordinate ML/rules with central Fraud and Data teams, and liaise with Compliance on SARs and loan abuse.
Top Skills: AIBi Visualization ToolsBlockchainMachine LearningProvenirPythonRSQLStablecoinsTaktileWhatsapp
Reposted 24 Days AgoSaved
In-Office or Remote
Des Moines, IA
Senior level
Senior level
Fintech • Financial Services
Lead quantitative credit analytics for a Send Now Pay Later (SNPL) product: build and maintain credit policies, pricing and NPV models, vintage analysis, portfolio monitoring, model integration/testing, and alternative data evaluation to optimize approval rates and manage portfolio health.
Top Skills: DbtMachine LearningPythonRSQL
Reposted 24 Days AgoSaved
Remote
Des Moines, IA
159K-215K Annually
Senior level
159K-215K Annually
Senior level
Information Technology • Security • Software • Cybersecurity
The Engineering Manager for Smart Signals leads a team, manages execution, and maintains technical depth in backend systems for fraud detection. They shape strategy and coordinate across teams to enhance product quality.
Top Skills: Backend SystemsFraud DetectionMachine LearningSecurity Signals
Reposted 24 Days AgoSaved
Remote
Des Moines, IA
150K-240K Annually
Senior level
150K-240K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning
The Senior Backend Data Engineer will extend data ingestion and processing pipelines, build APIs and backend services, and provide technical leadership.
Top Skills: Api GatewayAWSCognitoDynamoDBGoLambdaMachine LearningPythonRust
Reposted 24 Days AgoSaved
Remote or Hybrid
Des Moines, IA
250K-300K Annually
Senior level
250K-300K Annually
Senior level
Cloud • Digital Media • Enterprise Web • Marketing Tech • Software
Design, optimize, and scale ClickUp's search infrastructure using OpenSearch/ElasticSearch. Improve relevance, speed, and real-time indexing; build vector/semantic search capabilities; create measurement frameworks; integrate search with AI and product features; troubleshoot at scale; and mentor junior engineers to maintain high search quality under heavy load.
Top Skills: Distributed Data ProcessingElasticsearchMachine LearningNlpOpensearchSemantic SearchTypescriptVector EmbeddingsVector Search
Reposted 24 Days AgoSaved
Remote or Hybrid
Des Moines, IA
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Cloud • Digital Media • Enterprise Web • Marketing Tech • Software
Design, scale, and optimize ClickUp's search infrastructure using OpenSearch/Elasticsearch. Improve relevance, speed, and real-time indexing, build vector search capabilities, create evaluation frameworks, and collaborate with AI/backend/product teams to integrate and troubleshoot search at scale.
Top Skills: ElasticsearchMachine LearningNlpOpensearchTypescriptVector EmbeddingsVector Search
Reposted 24 Days AgoSaved
Remote
Des Moines, IA
155K-185K Annually
Senior level
155K-185K Annually
Senior level
AdTech
The Senior AI Data Engineer will design and build scalable data pipelines, ensure data quality, and support AI product development through a unified analytical data framework.
Top Skills: AIAirflowSparkAzure SynapseBigQueryClickhouseDatabricksDbtDelta LakeMachine LearningPrefectPythonSnowflakeSQL
Reposted 24 Days AgoSaved
Remote
Des Moines, IA
183K-224K Annually
Senior level
183K-224K Annually
Senior level
Fintech
The Principal Data Scientist will design, develop, and deploy machine learning models, innovating methodologies and collaborating across teams to enhance financial decision-making and risk management.
Top Skills: AirflowBentomlChalkDvcKubernetesMachine LearningMlflowNumpyPandasPydata StackScikit-LearnSpark
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