Top Senior Machine Learning Jobs in Des Moines, IA

Drive enterprise sales growth across North American banking, credit card, and financial services accounts. Develop strategic account and business development plans, build customer and partner relationships, close complex multi-million-dollar technology deals, and engage C-level stakeholders. Represent the company at industry events, collaborate with commercial and leadership teams, manage pipeline forecasting and reporting, and apply MEDDPICC methodology. The role focuses on cybersecurity, fraud prevention, authentication, and SaaS or cloud solutions, with 50% domestic and international travel.

Build and operate scalable ML infrastructure and platform capabilities across cloud and on-premises environments. Develop Python-based developer tooling, services, and production systems supporting experimentation, distributed training, model deployment, and operations. Lead complex initiatives from architecture through rollout, improve reliability and developer productivity, and partner with ML and infrastructure teams. The role emphasizes Kubernetes, AWS, distributed compute, GPU-intensive workloads, observability, and production excellence.

Lead the design, development, deployment, and monitoring of production AI/ML applications for dairy-farm intelligence. Responsibilities include data wrangling, feature engineering, model selection, experimentation, MLOps, agent evaluation, observability, fine-tuning, AI governance, and integration with cloud infrastructure. The role also drives AI adoption, establishes engineering practices, collaborates cross-functionally, and may build React and TypeScript user experiences.

Lead the design, development, deployment, and monitoring of production AI/ML applications for dairy farm intelligence. Responsibilities include data wrangling, feature engineering, model selection, experimentation, MLOps, agent evaluation, observability, fine-tuning, AI governance, and adoption enablement. The role also involves collaborating on React and TypeScript user experiences, translating ambiguous requirements into scalable systems, and communicating technical tradeoffs across product, engineering, and dairy science teams.

Own the technical side of deal progression for airline deployments: qualify opportunities, run demos and POCs, author integration and deployment architectures (PSS, APIs, data feeds, DNS, identity, networking), respond to RFPs/security questionnaires, scope SOWs and NFRs, and build reusable demo/reference assets to drive adoption and expansion while liaising between sales, engineering, and customers.

Lead the design, development, deployment, and governance of advanced analytics, machine learning, and AI solutions using large healthcare datasets. Responsibilities include data preparation, statistical and predictive modeling, model monitoring, explainability, visualization, stakeholder communication, and translating findings into clinical and operational improvements. The role also mentors data professionals, advises leaders, manages initiative priorities and risks, and promotes responsible AI and Agile practices.

You will tackle AI challenges, develop scalable software and collaborate with teams to enhance healthcare navigation using AI solutions.

Lead and transform the Fraud Intelligence Team into a high-impact function by improving operating models, QA, tooling, and metrics; build entry-level talent programs; connect labeling to measurable fraud prevention outcomes; deliver actionable insights to Product, R&D, Analytics, and GTM; and leverage AI and automation to increase productivity and business impact.

Partner with functional leaders to translate business strategy into people strategy. Own org design, performance management, compensation, talent development, engagement, and retention. Provide coaching on career pathing, change management, and sensitive employee issues. Use people data to generate insights and recommendations, build compliant HR policies, manage global employee relations, and collaborate with People Team COEs to deliver cohesive people programs at scale.

Serve as second-in-command for Coinbase Derivatives' Market Regulation Department, leading day-to-day regulatory compliance, managing exams and audits, advising on CFTC Core Principles, reviewing surveillance escalations and enforcement actions, and coordinating cross-functional regulatory workstreams to ensure the DCM meets obligations and resolves findings timely.

Develop and maintain open-source Python frameworks and ML developer tools, architect scalable libraries, grow early-stage projects, build real-time streaming capabilities, integrate modern frontend technologies, and collaborate with open-source contributors and the broader developer community.

The Staff Machine Learning Engineer will design and build scalable ML systems, mentor engineers, and drive AI strategy at SailPoint, focusing on AI-powered identity security solutions.

Drives operational excellence through data analysis, dashboards, process improvements, and cross-functional project leadership. The role embeds with business units to manage day-to-day operations, investigate trends, answer strategic questions, implement workflows, coordinate stakeholders, track deliverables, and present insights to technical and non-technical audiences. It serves as a strategic partner to operations leadership in a fast-paced, ambiguous environment.

Own the technical sales cycle for Databricks consulting engagements, including discovery, architecture design, solution scoping, estimation, proposals, demos, proofs of concept, workshops, and statements of work. Design lakehouse, data engineering, analytics, governance, security, and AI architectures. Partner with sales, Databricks, alliance, and delivery teams while ensuring effective handoffs into implementation.

Develop experimental AI techniques for agentic marketing applications, especially image and video generation. Build proofs of concept, autonomous evaluation and improvement systems, realistic AI-generated video, and brand-aligned creative generation workflows. The role requires strong quantitative and probabilistic thinking, backend architecture skills, creativity with LLM applications, and product intuition.

Lead and own cross-organizational technical programs for ML and robotics platform development, define roadmaps and milestones, remove blockers, align diverse engineering teams, and drive adoption of platform best practices to deliver scalable autonomy and infrastructure outcomes.

Define and execute the market strategy for UserTesting’s AI solutions. Own positioning, messaging, value propositions, go-to-market plans, sales enablement, customer and buyer research, competitive differentiation, thought leadership, and market feedback loops. Translate complex AI workflows and human-judgment applications into compelling solutions for technical enterprise buyers, while influencing product and company strategy through cross-functional leadership.

Owns the strategy, roadmap, development, and adoption of financial data products and APIs. Partners with data science and engineering to integrate predictive and machine-learning models into scalable, trustworthy capabilities. Defines quality metrics, requirements, documentation, and support models while ensuring privacy, security, regulatory compliance, and downstream adoption across consumer and business banking products.

Design, develop, and maintain high-performance, secure Java backend services and APIs. Ensure reliability, scalability, and cost-efficiency across microservices, databases, messaging systems, and capacity planning. Troubleshoot, profile, benchmark, and optimize systems (including ML applications) and collaborate with Kazakhstan stakeholders.

Design, develop, and validate functionally safe software for robotic perception systems. Build safety-critical architecture across Linux and real-time operating systems, create testing and validation frameworks for edge cases, collaborate with machine learning, hardware, and core software teams, and mentor junior engineers on safety-critical coding practices.

Drive MSSP partner growth across AMER by recruiting, onboarding, activating, and expanding strategic managed security service provider relationships. Develop territory recruitment plans, executive partnerships, joint business plans, and indirect routes to market. Help partners launch managed security services, generate pipeline, increase revenue, and accelerate time-to-revenue. Collaborate with sales, channel, marketing, services, and technical teams while managing forecasts, opportunities, executive reviews, and revenue objectives.

Lead AI-driven localization product initiatives from concept through production. Build strategic roadmaps, incubate machine-learning capabilities, partner with researchers and engineers, and deliver scalable tools for creators and content operations. Translate user needs into impactful products, communicate strategy to executives and nontechnical stakeholders, and use data, experimentation, and ML evaluation to prioritize work and measure outcomes.

Architect and operate North’s AWS and multi-cloud infrastructure, establishing IaC, CI/CD, security, observability, and disaster-recovery standards. Build AIOps capabilities including anomaly detection, predictive scaling, self-healing remediation, AI-assisted tooling, and cloud cost optimization. Collaborate with DevOps, SRE, Product Engineering, and InfoSec teams to deliver resilient, compliant, highly scalable platforms.

Own the end-to-end product direction and quality of an AI email application. Define AI and system requirements, translate model capabilities into product decisions, balance quality, cost, latency, reliability, safety, and user experience, and partner with ML, backend, and client engineers. Establish evaluation frameworks, quality standards, feedback loops, and failure recovery strategies while driving prioritization, execution, experimentation, and user trust in a zero-to-one environment.

Own the end-to-end product direction and quality of an AI-powered email application. Define AI and system requirements, evaluation frameworks, quality standards, and measurable outcomes. Partner closely with ML, backend, and client engineering teams to make trade-offs across quality, latency, cost, reliability, safety, and user experience. Drive prioritization, specifications, experimentation, failure-mode mitigation, and continuous iteration in a technical zero-to-one environment.