Jobs at Summit Therapeutics, Inc.

Leads global clinical trial site agreement development, budget strategy, contract and budget negotiations, payment forecasting, and site activation support. Partners with Legal, Finance, Clinical Operations, CROs, FSPs, and clinical sites to ensure compliant, cost-effective agreements and timely execution. Oversees vendors, resolves contract and payment issues, reports performance metrics, develops outsourcing strategies, and improves departmental processes across large, multi-site oncology trials.

Provides strategic and operational leadership across pharmaceutical development programs and portfolios. Oversees program strategy, prioritization, governance, timelines, risk management, scenario planning, executive reporting, and cross-functional execution across Research, Development, Regulatory, Manufacturing, and Corporate Strategy. Leads global late-stage oncology programs, supports regulatory approval, manages external partnerships, mentors program management leaders, and drives continuous improvement of program management processes and operating models.

Leads global compensation and benefits programs, including salary structures, incentive plans, equity, benefits, open enrollment, 401(k), leave administration, compliance, audits, and payroll coordination. Owns HR metrics, systems, policies, process improvements, change management, and AI-in-HR strategy. Partners with leadership, vendors, payroll, IT, and external stakeholders to improve employee experience and operational efficiency.

Leads marketing operations for a biopharmaceutical commercial organization, including promotional review committee workflows, content lifecycle management, speaker programs, events, vendors, budgets, marketing technology, fulfillment, and performance reporting. Partners with Marketing, Medical, Legal, Regulatory, Compliance, Commercial, agencies, and Finance to build scalable, compliant processes and support omnichannel initiatives, market access materials, product launches, and field execution.

Leads commercial analytics for ivonescimab, owning launch analytics, performance reporting, dashboards, metric definitions, targeting, segmentation, field resource allocation, and incentive compensation analysis. Builds self-service reporting tools and translates purchase, claims, EHR, lab, payer, hub, and omnichannel data into actionable insights. Establishes analytical standards, explains data limitations, supports patient journey modeling and forecasting, and partners with Sales, Marketing, Finance, Commercial Operations, Business Information, and Data & Technology teams.

Leads cross-functional pharmaceutical launch readiness projects, coordinating workstreams, governance, dashboards, KPIs, budgets, vendors, and stakeholder communications. The role supports product launches, indication expansions, lifecycle management, scientific communications, congress strategy, and post-marketing data generation. Responsibilities include developing project management processes, monitoring risks, driving accountability, managing external partners, and delivering executive-ready insights across commercial and medical affairs functions.

Owns the Veeva CRM platform supporting pharmaceutical Sales, Medical Affairs, Market Access, and field teams. Responsibilities include CRM strategy, roadmap development, implementation, configuration, integrations, data governance, release and vendor management, compliance, user support, and process optimization. The role partners with cross-functional leaders to improve field effectiveness, customer engagement, data quality, and operational performance across regulated commercial and medical operations.

Supports and optimizes corporate G&A applications for Finance, HR, and Legal, including NetSuite, Coupa, Agiloft, HRIS, and CLM systems. Translates business needs into technical requirements, manages application health, builds reports and dashboards, supports SOX ITGC controls and audits, coordinates testing and implementations, and develops training and documentation.

Provides Tier 1 and Tier 2 technical support through phone, email, and ticketing systems. Diagnoses hardware, software, network, and peripheral issues; manages devices, user accounts, permissions, inventories, and collaboration tools. Supports employee onboarding, documents incidents, maintains knowledge articles, and escalates complex issues. The role is onsite in Palo Alto and requires strong customer service, communication, prioritization, and judgment in an enterprise environment.

Manages global clinical study feasibility and start-up activities, including site agreements, budget negotiation, contracts, payment forecasts, vendor oversight, and site activation strategies. Partners with Clinical Operations, Finance, Legal, CROs, and clinical research sites to ensure regulatory compliance, timely activations, and cost-effective execution. Provides study metrics, resolves agreement and payment issues, supports process improvements, and oversees team deliverables for Phase 2 and Phase 3 trials.

The Director, Value Outcomes Liaison engages payers, health systems, P&T committees, pathway organizations, and policymakers to communicate clinical, humanistic, and economic evidence for ivonescimab. The role develops stakeholder relationships, supports formulary and pathway inclusion, collaborates with HEOR, medical affairs, and market access teams, communicates evidence gaps, and informs engagement strategies. Extensive healthcare and pharmaceutical experience, oncology knowledge, field-based market access expertise, and frequent travel are required.

Provides technical and statistical leadership for biologics analytical development and CMC activities, including method development, validation, transfer, comparability, stability, specifications, and lifecycle management. Reviews analytical data and external laboratory deliverables, develops statistically sound acceptance criteria and shelf-life models, supports investigations and regulatory submissions, and partners with Quality, Regulatory Affairs, manufacturing teams, CDMOs, and CROs to ensure scientifically robust and compliant analytical strategies.

Leads value-outcomes engagement with U.S. payers, health systems, pathway organizations, P&T committees, and policymakers. Provides objective clinical, economic, and humanistic information on ivonescimab; supports formulary, pathway, and treatment-order-set decisions; collaborates with medical affairs, HEOR, and market access teams; develops stakeholder relationships, communicates evidence, identifies evidence gaps, and informs access strategy. Requires extensive healthcare and pharmaceutical experience, oncology knowledge, field-based market access expertise, and up to 75% travel.

Provides strategic and operational leadership for global scientific publication activities in oncology, overseeing abstracts, manuscripts, posters, congress deliverables, compliance, publication systems, vendors, budgets, timelines, KPIs, and audit readiness. Partners with Medical Affairs, HEOR, Clinical, Commercial, Finance, Regulatory, Legal, and external stakeholders to ensure high-quality, compliant dissemination of scientific data.

Supports monthly close, R&D accounting, clinical trial accruals, CRO and investigator grant entries, and clinical site payments. Reviews invoices against agreements, maintains SOX controls, supports audits, prepares schedules, and ensures accurate financial reporting across Phase 2 and Phase 3 studies. The role collaborates with Clinical Operations and Study Start Up teams while improving processes, managing deadlines, and maintaining compliance.

Owns Summit’s federal account strategy for VA, VHA, DoD, DHA, and TRICARE systems ahead of oncology portfolio launch. Responsibilities include federal contracting readiness, FSS contract and pricing management, formulary and pathway access, account planning, stakeholder relationship development, reimbursement navigation, evidence coordination, and compliance with federal pharmaceutical regulations. The role is a senior individual contributor expected to build and lead the federal function as the portfolio expands.

Manages clinical pharmacology, pharmacokinetic, drug metabolism, and bioanalytical activities across drug development programs. Responsibilities include designing ADME studies, managing bioanalysis vendors, overseeing PK and ADA sample logistics, ensuring GCP compliance and data integrity, coordinating laboratories and chain of custody, and performing noncompartmental analysis and reporting. The role serves as a clinical pharmacology and DMPK subject matter expert on early- and late-stage cross-functional teams.

Lead global regulatory strategy for oncology programs from IND/CTA through BLA/MAA and post‑marketing. Provide cross‑functional regulatory leadership, lead due diligence for partnerships, mentor RA staff, drive labeling and risk‑mitigation strategy, liaise with global authorities, and support product launch activities with minimal oversight.

The Key Account Director develops strategic relationships with IDNs, academic centers, regional health systems, and community oncology networks to support market access and product adoption. Responsibilities include pathway and protocol inclusion, executive engagement, account planning, contract negotiation, reimbursement barrier resolution, cross-functional collaboration, quarterly business reviews, and market insight reporting. The role supports oncology product launches and requires extensive stakeholder relationships, oncology reimbursement expertise, and travel up to 50%.

Leads strategic market access and key account relationships across oncology IDNs, academic centers, health systems, and community networks. Develops account plans, drives clinical pathway and protocol inclusion, negotiates contracts, identifies reimbursement barriers, coordinates cross-functional teams, and provides market insights supporting product launches and adoption. The role engages executive, pharmacy, formulary, and P&T stakeholders and requires up to 50% travel.