About Summit:
Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence.
Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including:
Non-small Cell Lung Cancer (NSCLC)
HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.
HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.
HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.
Colorectal Cancer (CRC)
HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.
Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland.
Overview of Role:
The Director, Portfolio Strategy position reports to the Executive Director, Portfolio Strategy and Competitive Intelligence to support strategic planning activities by providing actionable recommendations based on assessments of markets and competitors, both existing and potential.
Role and Responsibilities:
- Lead and drive New Indication strategy and planning in several Oncology indications, working cross-functionally (e.g. Clinical, Regulatory, Commercial) to guide Summit’s portfolio for late-stage clinical development strategy
- Develop/refine framework and process for the New indication and overall portfolio strategy, providing thought leadership and supporting key strategic decision-making and investment decisions
- Deliver strategic market and competitive intelligence insights through research, scenario planning, and impact assessments to guide executive decision-making and Summit’s portfolio strategy.
- Deliver Disease Area strategy for new solid tumor indications by providing an overall integrated strategy and market assessment in partnership with R&D, Clinical, Medical, Commercial and Program teams
- Partner with BD team to provide strategic direction and guidance on business development opportunities
- Conduct deep analysis of competitors, products, and market trends, maintaining real-time awareness of landscape changes and translating insights into strategic implications for launch and also for pipeline indications
- Develop, lead and execute comprehensive market research plans (qualitative, quantitative, and competitive), selecting vendors, designing studies, interpreting results, and ensuring timely, high-quality deliverables.
- Develop NPV, forecasting and revenue modeling for new indications up to 18 months before launch, providing data-driven assumptions for early commercial planning.
- Lead TPP development and alignment with cross-functional team for several solid tumor indications
- Integrate market research and competitive intelligence into strategic planning, including brand plans, market access, and situation analysis.
- Maintain an in-depth understanding of oncology markets and data sources, synthesizing findings into a central knowledge repository for organizational use.
- Provide ad hoc analytical support to executive stakeholders to inform R&D, commercial, and business development decisions.
- Leverage best-in-class analytical methodologies and tools to interpret epidemiology, market, and customer data into actionable recommendations.
- Build and manage external partnerships—from market research vendors to data providers—ensuring quality, accountability, and cost-effectiveness.
Experience, Education and Specialized Knowledge and Skills:
- Bachelors degree in Biotech or related field; advanced degree (MS, PhD) preferred.
- Minimum of 10+ years of pharmaceuticals/biotech industry experience working with both qualitative and quantitative research in oncology/pharma market with emphasis on Non-Small Cell Lung cancer and other Solid Tumors is required.
- Strong understanding of the Solid Tumor Oncology landscape, including portfolio strategy, market planning, competitive intelligence, forecasting and key therapeutic areas such as lung cancer and colorectal cancer.
- Proven ability to identify and collect relevant market, customer, and competitor data; perform quantitative and qualitative analysis;
- Ability to translate complex findings into actionable market insights and strategic recommendations.
- Experience developing and executing primary and secondary market research, with exposure to global markets preferred.
- Proven experience leading, managing and executing end-to-end market research: designing research plans, synthesizing findings/insights, presenting, etc.
- Experience with advanced spreadsheets, patient-based forecast modeling including dynamic patient models, NPV modeling.
- Experience in facilitating competitive workshops, well-versed in TPP development with program and study teams is a plus.
- Use online market research and catalogue findings to databases.
- Strong communication and presentation skills.
- Skilled at PowerPoint, Excel and similar data tools.
- Ability to travel up to 25% of the time, depending on business needs.
This is the pay for this position
Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.
Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at [email protected] to obtain prior written authorization before referring any candidates to Summit.
Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.
Skills Required
- Bachelor's degree in Biotech or related field
- Advanced degree (MS, PhD)
- Minimum of 10+ years pharmaceutical/biotech industry experience with oncology and solid tumors
- Deep experience with qualitative and quantitative market research in oncology
- Proven ability to identify, collect, and analyze market, customer, and competitor data
- Experience designing and executing primary and secondary market research (vendor selection, study design, interpretation)
- Experience with advanced spreadsheets, patient-based forecast modeling, dynamic patient models, and NPV/revenue modeling
- Experience developing disease area strategy, portfolio planning, and market assessments for solid tumors
- Experience integrating market research and competitive intelligence into brand plans and market access strategies
- Skilled at PowerPoint, Excel and similar data tools; strong communication and presentation skills
- Ability to travel up to 25%
- Experience with global markets and international research exposure
- Experience facilitating competitive workshops and TPP development with program and study teams
- Ability to build and manage external partnerships with vendors and data providers
What We Do
Summit Mission Statement: To build a viable, long-lasting health care organization that assumes full responsibility for designing, developing, trial execution and enrollment, regulatory submission and approval, as well as successful commercialization of patient, physician, caregiver, and societal-friendly medicinal therapy intended to: improve quality of life, increase potential duration of life, and resolve serious medical healthcare needs. To identify and control promising product candidates based on exceptional scientific development and administrational expertise, develop our products in a rapid, cost-efficient manner, and to engage commercialization and/or development partners when appropriate. We accomplish this by building a team of world class professional scientists and business administrators that apply their experience and knowledge to this mission. Team Summit exists to pose, strategize, and execute a path forward in medicinal therapeutic health care that places Summit in a well-deserved, top market share, leadership position. Team Summit assumes full responsibility for stimulating continuous expansion of knowledge, ability, capability, and well-being for all involved stakeholders and highly-valued shareholders. Summit was founded in 2003 and our shares are listed on the Nasdaq Global Market (symbol ‘SMMT’). We are headquartered in Miami, Florida, and we have additional offices in Palo Alto, California, Princeton, New Jersey, Oxford, UK, and Dublin, Ireland.








