Top Remote Software Engineer Jobs in Charleston, SC

Lead Engineer responsible for end-to-end feature design, development, testing, and delivery of a cloud-based healthcare platform. Work full stack from database to frontend, design scalable data services and APIs, mentor junior engineers, ensure testing and security best practices, and deploy to modern cloud infrastructure.

Lead the design and evolution of predictive maintenance platform, build and scale ML-powered features, and mentor other engineers.

As a Senior Software Engineer, you'll develop and build tools for creative projects while leading feature development and collaborating with teammates.

Design, build, and operate backend systems for prediction markets, including order management, trade matching, settlement, and market resolution. Architect distributed, low-latency systems with strict financial correctness, lead multi-quarter technical projects, mentor engineers, and collaborate with Product, Compliance, and Risk to meet regulatory requirements.

Own architecture and delivery of core ledger and transaction processing systems. Design and build highly available, high-performance backend services, drive cross-team technical initiatives, establish platform standards, mentor engineers, and embed AI to improve operations and workflows.

Design, build, and operate the GraphQL API platform that routes high-volume traffic. Deliver end-to-end projects, improve reliability and performance, own SLOs and incident response, mentor engineers, and collaborate with product teams to evolve platform APIs and tooling.

Responsible for leading a team of engineers, supporting product development, identifying technical issues, and ensuring high-quality code delivery in backend systems at scale.

Build and own a vendor schema registry and semantic validation pipeline that ingests OpenAPI/Swagger/Smithy specs, tracks schema evolution, detects semantic and breaking changes, and provides SDKs and developer tooling to safely map vendor APIs into a canonical knowledge graph used by downstream teams.

Develop ML/RL models and infrastructure for AV simulations, optimize training loops, and support project timelines in autonomous vehicle tech.

Senior Software Engineer to design and deliver Golang-based microservices, mentor a small pod, estimate and implement features, produce unit and end-to-end tests, collaborate on design and code reviews, improve SDLC, and apply SRE observability practices while working with cloud-scale data stores such as Snowflake, DynamoDB, and Cassandra.

Build and ship backend features using Python, FastAPI, Postgres, and external integrations. Develop AI agents for sourcing, enrichment, summarization, extraction, classification, and routing. Create reliable prompts and structured outputs, evaluate agent quality, and add tests, logging, and observability. Work remotely with founders and users in a fast-moving environment.

Build and launch customer-facing AI product features across the full stack. Develop React and TypeScript web applications, Python and TypeScript backend services, APIs, and PostgreSQL data models. Integrate LLMs, third-party APIs, and customer data sources; deploy and operate services on AWS; and improve performance, reliability, observability, and security. Collaborate with founders, product leaders, designers, and customers while owning projects from problem definition through production.

Build and maintain SaaS product features across backend, frontend, databases, and cloud platforms. Write testable code, participate in reviews and system design, use AI-assisted development tools, support cloud deployments and monitoring, troubleshoot production issues, and document work. Collaborate with product managers, designers, and engineers while developing scalable software and growing across the technology stack.

Architect and develop the frontend and full-stack features for Legion, a real-time Command and Control platform managing large autonomous aircraft swarms. Responsibilities include distributed collaborative infrastructure, telemetry and sensor-data visualization, scheduling and data-link interfaces, deployment, CI/CD, QA, and DevSecOps. The role requires building high-performance web applications with React or a comparable framework, potentially incorporating geospatial interfaces, video streaming, and WebGL/OpenGL.

Lead design and development of scalable, cloud-native AI healthcare payment integrity platforms. Provide technical leadership, own production code and releases, design data/retrieval architectures, ensure observability, security, and compliance, and collaborate with ML, product, and architecture teams to deliver performant SaaS solutions.

Full Stack Software Developer responsible for designing, building, testing, and deploying scalable member-facing and internal applications. Work includes building APIs, database components, cloud-native solutions, CI/CD pipelines, and adopting AI-assisted development practices while collaborating in an Agile environment to improve member digital experiences.

Design and implement the core components of the Agents Python framework, focusing on API and abstraction development for AI-driven applications.

Design and develop functionalities for the Agents framework, iterate on feedback, and create documentation while working with various programming languages.

Develop fullstack web applications, enhance platform performance, collaborate on high-impact opportunities, and ensure stable, scalable solutions. Engage in rapid iterations and be a committed team player.

Build and maintain scalable, highly available payments risk systems that detect, mitigate, and resolve fraud and other malicious activity. Develop service-oriented APIs, real-time risk services, vendor and payment-network integrations, monitoring, and alerting. Collaborate with product managers, data scientists, operations, and engineering teams to evolve risk strategies, deliver product features, conduct experimentation, and maintain high engineering standards.

Develop and maintain scalable backend services and APIs for Twilio’s communications platform. Responsibilities include software design, development, deployment, code reviews, production operations, releases, on-call support, and technical documentation. The role requires collaboration within a small engineering team and the ability to explain complex technical concepts clearly.

Designs, develops, tests, deploys, maintains, and supports enterprise software applications using C#, .NET, ASP.NET Core, SQL Server, APIs, and related technologies. Owns application performance, reliability, scalability, troubleshooting, and continuous improvement. Serves as a technical subject matter expert, contributes to architecture and technology decisions, partners with DevOps on CI/CD automation, and mentors engineers. Collaborates with business stakeholders, product owners, vendors, and project teams throughout the software development lifecycle.

Build and own Dia’s enterprise administration products, including the Admin Console, entitlement and provisioning APIs, identity and policy configuration, usage metering, commerce integrations, and Atlassian Admin Hub integration. Partner with platform and client engineers to deliver enterprise features across web and native clients, establish technical direction, and shape the enterprise roadmap in a high-ambiguity startup environment.

Designs, develops, and maintains infrastructure for ML pipelines and CI/CD. Analyzes infrastructure performance, collaborates with data and software teams, manages feature stores and model registries, writes maintainable code, and documents technical processes. The role requires experience with cloud, big-data, programming, workflow orchestration, version control, and continuous integration technologies.

Build and maintain performant, accessible consumer-facing experiences for Netflix’s iOS app using Swift and GraphQL. Collaborate with product managers, designers, and engineers to scope projects, refine interfaces, develop shared infrastructure, and make architectural trade-offs. Teams may focus on client foundations, server-driven UI, advertising frameworks, or ad insertion. Responsibilities include writing robust maintainable code, automation, documentation, and supporting high-quality, scalable mobile experiences.