Top Program Director Jobs

Leads global oncology programs from discovery through commercialization and lifecycle management. Defines asset strategy, manages cross-functional global program teams, oversees budgets, resources, risks, timelines, regulatory objectives, and patient access initiatives. Provides matrix leadership, executive reporting, stakeholder management, and strategic support for feasibility studies, licensing opportunities, and business initiatives across multiple development phases.

Leads research program strategy and execution across drug discovery and preclinical development. Develops integrated plans, budgets, milestones, governance, risk mitigation, reporting, and portfolio recommendations. Coordinates internal teams, CROs, and external partners; drives decision-making, operational excellence, and on-time delivery. Provides financial analysis, forecasting, stakeholder influence, and senior leadership escalation while mentoring program managers and scaling enterprise program-management capabilities.

Leads proactive, risk-based quality strategies across clinical development programs. Advises governance bodies on quality risks, oversees serious breach investigations and corrective actions, drives global GCP inspection readiness, designs audit strategies, and supports regulatory interactions. Mentors quality and study execution teams while advancing compliance, patient safety, data integrity, and continuous improvement across clinical trial delivery and pharmacovigilance.

Leads global pharmaceutical programs from discovery through commercialization and lifecycle management. Defines asset strategy, directs cross-functional global program teams, manages budgets, resources, risks, timelines, regulatory progress, and executive governance reporting. Partners across research, clinical, commercial, CMC, and other functions to maximize asset value, achieve approvals, support global launches, and improve patient access. May oversee multiple complex programs and evaluate new business opportunities.

Leads strategy, scientific direction, risk management, and execution for complex global CMC pharmaceutical development programs. Provides technical expertise across pharmaceutical sciences, process engineering, manufacturing development, regulatory requirements, and experimental statistics. Represents CMC in governance and cross-functional initiatives, develops teams and capabilities, mentors staff, evaluates innovative solutions, and communicates program strategies and business cases to stakeholders. Requires extensive pharmaceutical development experience and leadership of multidisciplinary programs.

Leads strategy, planning, oversight, and delivery of clinical development program operations across global studies. Serves as the operational representative to development governance teams, develops program operational plans, manages timelines, budgets, risks, vendors, and CRO performance, and ensures quality, ethical, and timely clinical study execution. Influences matrix teams, supports strategic decisions, and contributes to clinical development plans, due diligence, and resource planning.

Lead operational, clinical, and administrative functions for a substance use disorder treatment program. Responsibilities include supervising and training staff, managing census and budgets, maintaining licensing and accreditation, overseeing daily operations and safety, implementing policies and process improvements, coordinating with regulatory and community organizations, monitoring quality metrics, and participating in multidisciplinary treatment planning.

Directs elementary afterschool programming, supervises and develops staff, supports youth mental health and inclusion, manages school and community partnerships, ensures regulatory and funding compliance, analyzes program data, coordinates events, supports grant development, and resolves on-site issues. The role requires collaboration with schools, NYPD, government agencies, families, and community organizations while supporting programming during weekdays, evenings, and weekends.

Teach undergraduate and graduate social work courses, conduct scholarship, advise students, and support curriculum development. Direct the MSW program through administration, assessment, CSWE accreditation compliance, strategic planning, faculty collaboration, recruitment, student success, and community partnerships. Participate in university governance and professional service while supporting ethical and competent social work practice.

Leads HOPE’s workforce development program operations across Brooklyn and Bronx sites. Oversees senior staff, placement and retention outcomes, operating standards, data integrity, dashboards, employer partnerships, and funder reporting. Drives consistent processes across training tracks, coordinates corrective action, supports staff development, and represents the organization with partners and stakeholders. The role focuses on green economy workforce initiatives and requires extensive on-site work, including occasional evening and weekend hours.

Leads financial management for the F117 military engine program, including P&L and balance sheet performance, forecasting, long-range planning, risks and opportunities, business cases, proposals, and contract negotiations. Partners with senior executives and cross-functional teams to improve financial processes, reporting, and automation. Manages and develops a high-performing finance team while supporting strategic and operational decision-making.

Leads a senior technical project and program management organization overseeing complex engineering programs, product strategies, budgets, schedules, and customer-impacting initiatives. Develops long-range plans, aligns programs with business objectives, establishes performance metrics, and guides engineering managers. Partners with senior leadership and internal and external customers to address high-value problems, improve processes, and deliver division-wide results.

Leads the delivery, quality, and development of Clinical Scientists supporting clinical trials, eCOA, endpoint quality, data analytics, and product development. Oversees training, coaching, quality assurance, SOPs, clinical methodology, proposal support, customer relationships, and cross-functional initiatives. Requires Japanese and English fluency, clinical research expertise, scientific communication skills, and knowledge of statistics and analytics. The role supports APAC and involves travel of up to 25%.

Leads enterprise technical programs and strategic platform roadmaps focused on modernization, scalability, resilience, and business alignment. Owns executive communications, program governance, investment prioritization, and architectural decisions. Establishes TPM operating models and best practices, mentors TPM leaders, and drives delivery accountability across multiple domains. The role requires extensive experience with distributed systems, cloud architecture, Agile delivery, large-scale platforms, regulated environments, and cross-functional technical leadership.

Leads complex technical programs and cross-platform initiatives across Capital One’s card technology portfolio. Establishes TPM operating models, roadmaps, maturity frameworks, and scalable tooling; aligns architecture and dependencies; manages risks and executive escalations; and drives measurable platform outcomes across engineering teams. Requires strong experience with distributed systems, cloud architecture, Agile delivery, regulated environments, organizational influence, and large-scale technical program execution.

Directs an inpatient psychiatric program serving adults and geriatrics. Supervises, recruits, and evaluates staff; coordinates quality patient care; manages clinical and operational outcomes; provides community education; and handles conflict resolution and problem-solving. The role offers a Monday-Friday schedule without weekends or on-call responsibilities.

Leads and grows a federal owner’s representative program, overseeing capital projects from business case and design through procurement, construction, commissioning, occupancy, and closeout. Responsibilities include cost and schedule control, risk and change management, acquisition support, stakeholder coordination, construction oversight, executive reporting, and governance. The role also supports business development and proposals, applies commercial delivery practices in federal environments, and requires travel to customer and project sites.

Oversees the operations, clinical functions, financial performance, quality improvement, marketing, staff, and strategic growth of an outpatient wound care program. Manages hospital relationships, referral development, revenue cycle activities, regulatory compliance, performance improvement, and patient care coordination. The role may provide direct wound care, case management, and hyperbaric services while leading clinical and non-clinical staff.

Leads governance for pharmaceutical digital and channel marketing across brands. Establishes compliant channel standards, workflows, audit strategies, content requirements, and risk controls. Partners with marketing technology, privacy, regulatory, medical, and operations teams to launch capabilities across email, EHR, and SMS. Oversees approval processes, gathers requirements, defines specifications, tests solutions, manages cross-functional stakeholders, supports audits, and improves marketing operations through Agile optimization.

Leads complex, cross-functional technology programs and strategy initiatives across Asset & Wealth Management. Responsibilities include defining technology priorities, analyzing trends and competitors, developing strategic recommendations, managing roadmaps, resources, budgets, risks, and workstreams, and advising senior executives. The role requires strong stakeholder influence, executive communication, consulting expertise, and the ability to align AI, digital transformation, cloud, analytics, and infrastructure initiatives with business objectives.

Leads and scales 2K’s technical program management practice supporting multiple game studios. Owns program delivery strategy, governance, executive reporting, staffing, roadmap execution, risk escalation, prioritization, and cross-functional alignment. Builds and develops high-performing Technical Program Manager teams while establishing processes and tools that improve delivery visibility and outcomes across shared services and platform initiatives.

Leads the Illinois Small Business Development Center at the Polsky Exchange by advising small businesses, managing advisors and personnel, overseeing budgets and operations, coordinating programs, cultivating community and partner relationships, ensuring grant compliance, tracking outcomes, maintaining CRM records, producing reports, and developing marketing and funding resources.

Leads large-scale technical programs, platform transformations, and cross-platform investment planning. Establishes TPM operating models, roadmaps, measurable platform outcomes, and delivery accountability across engineering teams. Serves as an executive escalation point, drives architectural alignment and tradeoffs, and develops TPM organizational maturity, tooling, and talent. Requires strong technical leadership, business communication, and experience delivering complex programs in regulated environments.

Leads and builds the Technical Program Management function, manages technology portfolios, establishes governance and delivery practices, and advises executives on priorities, capacity, risks, investments, and tradeoffs. Supervises and develops Technical Program Managers, oversees roadmaps, backlogs, dependencies, vendors, and delivery outcomes, and coordinates cross-functional technology initiatives using Jira, Confluence, and related enterprise platforms.

Manages implementation and relationship management for a portfolio of higher-education partners. Responsibilities include developing implementation plans, supporting program adoption and retention, managing renewals and contracts, tracking progress in HubSpot and Asana, analyzing partner data, coordinating cross-functional teams, communicating with stakeholders, and improving implementation processes. The role requires strong project management, presentation, relationship-building, analytical, and higher-education partnership skills.