Project Manager Jobs in Durham, NC

Manages federally and state-funded hazard mitigation projects across multiple counties, including property acquisition, construction, home elevation, and generator installation. Oversees schedules, scopes of work, reimbursements, compliance, contractors, local governments, and customers. Conducts project-site inspections, verifies construction progress and safety, maintains records, and resolves issues to meet strict performance deadlines.

Manages domestic, regional, and global clinical research projects in oncology or ophthalmology. Oversees project teams, client communications, scope, schedules, budgets, risks, quality, regulatory documentation, and stakeholder expectations. Leads delivery and change control, manages resources and KPIs, resolves issues, supports business development, and may provide line management, mentoring, training, and talent development.

Plans and manages multidisciplinary clinical research projects from initiation through delivery, ensuring studies meet timelines, budgets, quality standards, and regulatory requirements. Responsibilities include managing project plans, risks, resources, budgets, profitability, vendors, communications, training, performance metrics, and client relationships. The role also supports bid defenses, process development, and customer satisfaction initiatives.

Leads clinical study delivery from planning through execution, ensuring contractual, quality, timeline, and financial objectives are met. Builds and directs cross-functional project teams, manages risks, issues, vendors, scope changes, customer relationships, and study milestones. Develops study management plans, monitors performance, supports bid defenses, oversees project finances, implements corrective actions, and mentors less experienced team members. Applies clinical trial, drug development, regulatory, and therapeutic expertise to improve operational execution and customer satisfaction.

Leads eCOA implementation projects through startup, managing timelines, budgets, scope, invoices, risks, vendors, translations, configurations, and sponsor communications. Coordinates global clinical teams, presents status updates, maintains compliance and financial reporting, drives process improvements, supports proposals, and mentors new hires. Requires occasional domestic or international travel for sponsor meetings.

Manages commercial and industrial paving projects from estimation through closeout. Responsibilities include preparing bids and cost estimates, reviewing specifications, coordinating clients, suppliers, subcontractors, crews, schedules, equipment, and staffing, managing project risks and changes, resolving disputes, maintaining safety and quality standards, and ensuring profitable, timely execution. The role also prepares CADD drawings, analyzes field data, performs administrative duties, and oversees multiple projects.

The Senior Project Manager oversees the project portfolio for a biopharmaceutical commercial manufacturing facility. Responsibilities include tracking major GxP, capital, process improvement, technology transfer, new product introduction, and operational readiness projects; leading strategic initiatives; supporting portfolio governance; and improving project management practices through coaching, training, and standardization. The role also requires collaboration with site leadership and management of project budgets, processes, and cross-functional stakeholders.

Lead global and multi-regional clinical studies from startup through closeout, managing timelines, quality, budgets, risks, regulatory compliance, sponsors, and cross-functional teams. Develop study management plans, monitor performance, oversee financials, support proposals, communicate with stakeholders, and mentor project staff while ensuring adherence to ICH-GCP and applicable regulations.

Manage cross-functional operational and inspection readiness initiatives in a regulated life sciences environment. Coordinate action plans related to deviations, CAPAs, and process improvements; track milestones, risks, dependencies, corrective actions, and deliverables; facilitate stakeholder meetings and issue resolution; maintain dashboards and leadership reports; support gap assessments, documentation, evidence collection, and inspection preparation; and deliver project summaries and lessons learned.

Manages Phase I–IV clinical trials from startup through closeout, overseeing project plans, resources, budgets, timelines, quality, and operational delivery. Leads cross-functional and external teams, coordinates subcontractors, resolves conflicts, develops contingency and rescue strategies, and ensures customer and regulatory expectations are met. Requires clinical pharmaceutical or CRO experience, knowledge of ICH/GCP requirements, project management expertise, and domestic and international travel availability.

Leads clinical study planning and execution for immuno-oncology and cell and gene therapy trials. Responsibilities include developing study plans, managing cross-functional teams, monitoring risks and milestones, maintaining regulatory compliance, overseeing vendors, managing budgets and forecasts, supporting client relationships, and mentoring project staff.

Leads IT project delivery for digital account management products and services. Implements project management and scaled delivery practices, improves collaboration, drives continuous improvement, and coordinates cross-functional teams through end-to-end development and iterative deployments. Partners with Product and Engineering leaders to prioritize work, resolve roadblocks, manage organizational change, and deliver business and technology solutions efficiently, collaboratively, and at speed.

Manage client-facing biotechnology and bioanalytical programs from coordination through delivery. Responsibilities include timelines, milestones, stakeholder communication, meetings, financial milestone tracking, risks, escalations, contract amendments, dashboards, and cross-functional collaboration across operations, quality, finance, and proposals. Senior-level work includes independent ownership of complex concurrent programs, client advocacy, budget and scope alignment, and proactive issue resolution.

Lead and deliver medium-to-large multi-regional clinical studies in CNS therapy areas. Own study strategy, planning, finances, risk management, cross-functional team leadership, client relationships, quality, and regulatory compliance to meet contractual milestones and drive operational excellence.

The Senior Project Manager will lead multiple clinical drug trials, manage customer relationships, coordinate team activities, and ensure successful project execution.

Lead utility-scale battery energy storage projects from contract execution through commercial operation. Coordinate engineering, software integration, supply chain, construction, commissioning, commercial, and customer teams while managing scope, schedule, budget, risk, quality, safety, and customer commitments. Implement PMO governance, project controls, stage-gate reviews, executive reporting, issue resolution, and continuous improvement across the project portfolio.

Owns portfolio governance, executive reporting, RAID and action management, resource planning, delivery-process governance, financial tracking, meeting operations, and continuous improvement across multiple customer engagements. Coordinates technical, customer-facing, financial, and operational stakeholders while maintaining accurate schedules, forecasts, risks, decisions, and portfolio health information. Develops governance standards, SOPs, training materials, and playbooks, and facilitates leadership reviews, retrospectives, and follow-through.

Lead end-to-end delivery of global real-world observational oncology studies within an FSP model: manage cross-functional teams, vendors, budgets, timelines, study documentation, regulatory compliance, risk mitigation, metrics reporting, and continuous improvement.

Manage low-to-medium complexity IT infrastructure projects end-to-end: deliverables, quality, schedule, budget, scope, governance, communications, risk, and client relationships. Ensure projects meet cost, time, and quality constraints while working on-site with clients.

Manage survey project scope, schedule, budget, and quality. Coordinate stakeholders and municipalities, make technical survey/staking decisions, review deliverables, maintain client relationships, ensure crew safety, and mentor staff.

Manage New Technology Introduction (NTI) projects for SiC power products from concept through commercialization. Lead cross-functional teams to qualify devices to industrial and automotive standards, drive performance modeling, risk mitigation, testing, reliability, DFMEA/DVP&R, and handoff to operations. Coordinate schedules, material and fab starts, and communicate status and risks to stakeholders to ensure timely product release.

Lead healthcare architecture projects from scope through construction administration: manage project teams, budgets, schedules, and client/consultant communication; use Deltek for project controls; ensure code compliance, construction administration, risk management, and staff mentoring while supporting business development.

Supports the Senior Technical Project Manager throughout laboratory project lifecycles, including project setup, launch, task monitoring, quality control, sample inventory, documentation, and data integrity. Reviews laboratory records against SOPs and ensures compliance with laboratory protocols, safety standards, FDA guidelines, and ISO 17025. The role requires strong organization, proofreading, prioritization, interpersonal, and documentation skills while working onsite in a Durham laboratory.

Manage low-to-medium complexity IT infrastructure projects end-to-end: define requirements, govern scope, schedule and budget, mitigate risk, control change, lead teams, report to stakeholders, and ensure handover to service while supporting business development and PM best practices.

The Project Manager will organize meetings, maintain project plans and budgets, and provide feedback on methodologies, with a focus on Agile and related tools.