Top Senior Machine Learning Jobs in Des Moines, IA

Partner with customers to design and deliver production-ready AI/ML solutions, drive POC-to-production success, troubleshoot technical issues, inform product roadmap with customer feedback, and communicate outcomes to stakeholders.

The Senior Data Engineer will own the data strategy, managing sourcing, structuring, and optimizing multimodal data to enhance AI models and products.

As a Senior Software Engineer, you'll build and operate the ML platform, optimizing data operations, managing the feature store, and supporting ML initiatives while driving architectural roadmap decisions.

The Staff Engineer will architect and build AI and ML infrastructures, mentor engineers, and lead high-impact initiatives to enhance ML capabilities across Attentive's platform.

As a Senior Machine Learning Engineer, you will develop and deploy AI-driven products to enhance clinical trials, collaborating with teams to improve patient care through scalable machine learning solutions.

Own and evolve ClickHouse's Python connector and SDKs; build and maintain integrations with orchestration and transformation tools; design AI/LLM integration patterns (RAG, embeddings, feature stores); engage with open-source community; collaborate with Product and Cloud teams to prioritize and ship production-grade data integrations.

Develop AI/ML-powered features in ClickHouse Cloud, focusing on frontend and API architecture, UI/UX, and integrations with AI systems.

Lead development of cutting-edge LLM and Agentic AI systems for Airbnb customer support, from research and prototyping to production deployment. Collaborate with product, design, and engineering to build scalable ML infrastructure, improve model performance, and implement evaluation, fine-tuning, and guardrails for chat and voice assistants.

Lead design, build, and operation of end-to-end production ML systems (feature pipelines, training, inference, experimentation, monitoring) for ranking, recommendation, rewards, ROAS/LTV prediction, personalization, and offer optimization in a high-scale AdTech environment. Provide hands-on technical leadership, mentor engineers, drive MLOps and observability standards, and partner with Data Engineering, BI, Product, and business teams to connect models to outcomes.

Develop and tune ML models, productionize and deploy strategies for ML systems, and align cross-functionally to communicate performance metrics.

As a Staff Machine Learning Engineer, you will develop, productionize, and deploy ML models for clinical use, ensuring real-world effectiveness through hands-on coding and infrastructure building.

The Staff Machine Learning Engineer will develop and maintain MLOps tools, optimize model performance, and collaborate on ML system architecture with a focus on enhancing developer experience.

Lead end-to-end development of fraud and risk ML systems: define problems, engineer features, build and evaluate models, collaborate with product and engineering, deploy with ML engineers, and monitor production performance to detect drift and trigger retraining.

Lead AI/ML consulting engagements, build and deploy machine learning models and ETL pipelines, analyze large datasets, design data architectures, deliver visualizations, drive business development, and manage client-facing teams in high-stakes situations.

As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.

Develop and deploy machine learning solutions for autonomous truck applications: EDA, deep learning model development, embedded deployment, data ingestion/curation, analytics, visualization, technical leadership, and process improvement across manufacturing and business domains.

Build and design backend services, AI agents, and machine learning models. Collaborate cross-functionally to deliver AI features and maintain code quality.

As a Senior Machine Learning Engineer at ZoomInfo, you will enhance core datasets through ML/NLP solutions, manage entity resolution tasks, and drive cross-functional impact by mentoring teams and collaborating on ML KPIs.

Lead technical execution across backend, frontend, mobile, AI, and data. Translate ambiguous product goals into technical plans, unblock hard engineering problems, coordinate cross-domain work, raise engineering quality, define hiring needs and technical evaluation standards, and build internal AI workflows to foster an AI-native engineering culture.

Lead technical pre-sales and enterprise rollouts by owning infrastructure strategy, PoCs, migrations (on‑prem to cloud), DMS/CRM integrations, InfoSec discussions, and stakeholder engagement with C-level sponsors to enable scalable deployments and upsell opportunities.

Lead program delivery for engineering teams at Arine, optimizing internal processes and ensuring timely execution of technical programs while facilitating Agile methodologies.

The AI Director will oversee ML bot development and implementation, identify AI opportunities, educate teams, and prototype AI solutions.