Top Senior Machine Learning Jobs in Des Moines, IA

Build and maintain backend services and infrastructure for ML and generative AI features. Develop scalable, resilient, high-performance Python services (async frameworks, streaming), deploy to Kubernetes, integrate RAG and LLM orchestration, instrument LLM observability, and collaborate cross-functionally to deliver production-ready AI products.

The Senior Machine Learning Engineer will manage the full ML lifecycle, collaborating with teams to develop scalable systems that improve product decisions and empower monetization strategies.

Lead design, deployment, and monitoring of predictive models for credit risk, collections, and operations. Drive adoption of modern ML and MLOps, mentor data scientists, define strategic roadmap, advise senior leadership, and ensure model governance and regulatory compliance.

Lead the end-to-end machine learning lifecycle for AI products, managing data pipelines and model development to optimize performance and accuracy in production.

Lead research on humanistic AI for autonomous systems. Collaborate with teams, design experiments, and publish findings in top-tier publications.

Lead and scale Vibrant's data science, ML, and AI function: set strategy and governance, oversee applied research and production ML (especially NLP), ensure HIPAA-compliant deployments, partner with execs and engineering, recruit and mentor teams, and deliver measurable outcomes for crisis services and enterprise initiatives.

Lead a Machine Learning engineering team owning mission, execution, morale, and code quality. Partner with product to deliver roadmap, remove roadblocks, improve processes, coach and grow engineers, and drive development, deployment, and innovation of ML models for recommender, search, and matching systems.

Design and lead end-to-end applied AI architectures (predictive ML, MLOps, generative AI, LLMs, RAG, agentic workflows), translate business needs into production-ready solutions, prototype and deliver implementations, and ensure security, observability, governance, and operational reliability.

Design and improve ML training frameworks, modularize experiments, adapt fire-hazard detection algorithms for varied electrical environments, build scalable pipelines for high-frequency sensor data, and develop dashboards and tooling to monitor model performance and drift while collaborating across product, data science, and fire safety teams.

Lead a team of data scientists developing ML-driven products, managing infrastructure, training models, and ensuring production quality while collaborating with senior leadership.

The AI/ML Engineering Manager leads a team of ML engineers and architects, managing hiring, performance, and customer engagements while providing technical guidance in ML operations and architecture.

Design, evaluate, and productionize generative AI/ML solutions (RAG, agents, embeddings, retrieval). Build evaluation frameworks for hallucination detection, benchmark LLMs, optimize prompts/models, create datasets, fine-tune models, and collaborate to deploy and monitor enterprise-scale GenAI systems.

Lead development of scalable AI/ML capabilities for Mail Intelligence: build LLM- and ML-based personalization, data pipelines, tools, and observability. Mentor engineers, collaborate cross-functionally, run A/B tests, implement feedback loops, and balance cost/quality/speed tradeoffs to deliver production-grade solutions.

The role involves applying AI/ML techniques to develop model systems for healthcare, collaborating across teams, and conducting R&D.

Lead the development of device intelligence and fingerprinting systems by designing backend services, collaborating on integrations, and applying advanced machine learning algorithms to enhance security and combat fraud.

Lead and grow the AI/ML Engineering team, manage core AI/ML platform development, ensure production-grade service operational excellence, and develop product strategies.

Build and productionize large-scale ML models and pipelines for query understanding and personalization. Work on autocomplete, query tagging/NER, query expansion, intent modeling, and LLM-powered natural-language search. Collaborate cross-functionally to design, deploy, and monitor batch and real-time systems, leveraging modern ML infrastructure and tooling to improve search relevance across Airbnb products.

Build and productionize ML models and data infrastructure to analyze millions of chaos engineering experiments, detect and explain failures, recommend automated remediation, and integrate AI-driven failure analysis into Gremlin's product using techniques like causal inference, graph ML, time-series modeling, and reinforcement learning.

Lead architecture and technical strategy for Lyra's ML and generative AI platform. Design training, fine-tuning, and low-latency inference infrastructure (RAG, vector DBs), set ML/AI SDLC standards (dataset lineage, CI/CD, evaluation, monitoring), partner with cross-functional clinical and product teams, mentor senior engineers, deliver prototypes and critical code, and ensure secure, reliable production ML systems.

The Senior Manager, Data Science/ML will lead a team to enhance product innovation through data science, focusing on ML and experimentation frameworks that boost customer engagement. Responsibilities include defining product strategy, building ML models, and collaborating with cross-functional teams to shape product roadmaps.

The Senior ML Engineer will automate component placement on PCBs, working on R&D and production using ML and optimization techniques.

As a Senior/Staff ML Systems Engineer at Quilter, you'll design and maintain ML infrastructure for automated PCB component placement, manage data pipelines, and lead systems design reviews while ensuring project efficiency and reliability within a fully distributed team.

The role involves managing the ML lifecycle, developing scalable ML systems, and collaborating on AI-first product solutions focusing on Large Quantitative Models.

As a Senior Machine Learning Engineer, develop LLM evaluation frameworks and agentic AI workflows to extract insights from conversations and optimize customer experiences.

Build and expand in-database ML model catalog: implement new model types, ensure framework parity with scikit-learn/Spark ML, optimize training and inference at petabyte scale, extend SQL-level linear algebra, and collaborate across teams to deliver correct, performant ML features and documentation.