Top Senior Machine Learning Jobs in Des Moines, IA

Reposted 2 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Other • Sales • Software
As a Senior Machine Learning Engineer, develop LLM evaluation frameworks and agentic AI workflows to extract insights from conversations and optimize customer experiences.
Top Skills: Hugging FaceLlmNlpNltkPyTorchSpacyTensorFlow
Reposted 2 Days AgoSaved
Remote
Des Moines, IA
196K-227K Annually
Senior level
196K-227K Annually
Senior level
Real Estate • Travel • PropTech
Lead development of cutting-edge LLM and Agentic AI systems for Airbnb customer support, from research and prototyping to production deployment. Collaborate with product, design, and engineering to build scalable ML infrastructure, improve model performance, and implement evaluation, fine-tuning, and guardrails for chat and voice assistants.
Top Skills: Agentic AiAutogenDistillationGrpoLanggraphLlmLlm Evaluation FrameworksMl InfrastructureMlopsModel ServingMulti-Agent OrchestrationPretrainingPrompt EngineeringRagReactRlhfSft
Reposted 2 Days AgoSaved
Remote
Des Moines, IA
119K-217K Annually
Senior level
119K-217K Annually
Senior level
Kids + Family • Mobile
Build and operate high-throughput experimentation and recommendation infrastructure. Design APIs and services, use agentic AI workflows (LLMs) for development, ensure performance and reliability, participate in on-call, mentor teammates, and codify AI-native engineering practices.
Top Skills: Apache KafkaAWSClaude CodeConfluent CloudConfluent PlatformContainerized DeploymentsCursorDatadogFeature StoresFlinkGithub ActionsGithub CopilotGrafanaJavaKafka StreamsLlmsMavenNexusPrometheusSchema RegistrySpring Boot
3 Days AgoSaved
Remote
Des Moines, IA
150K-187K Annually
Senior level
150K-187K Annually
Senior level
Fintech
Build and evolve core ML platform infrastructure—feature stores, real-time scoring, deployment, monitoring, and data access. Drive architecture and technical decisions, ensure reliability at scale, mentor engineers, partner with data scientists, and lead complex projects from design to production.
Top Skills: AirflowApache BeamArgocdBigQueryBigtableDatadogDockerFastapiFirestoreGoogle Cloud StorageJavaKubernetesNode.jsPub/SubPythonRedisSnowflakeSQLTerraformVertex Ai
Reposted 3 Days AgoSaved
Remote
Des Moines, IA
240K-270K Annually
Senior level
240K-270K Annually
Senior level
Food
The Senior Manager, Data Science/ML will lead a team to enhance product innovation through data science, focusing on ML and experimentation frameworks that boost customer engagement. Responsibilities include defining product strategy, building ML models, and collaborating with cross-functional teams to shape product roadmaps.
Top Skills: AirflowAWSGCPKubeflowMlflowPythonPyTorchScikit-LearnSnowflakeSQLTensorFlow
Reposted 3 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning
Lead development and maintenance of internal Python SDK frameworks and agentic workflows, build scalable FastAPI-based ML APIs, automate CI/CD with Jenkins and GitLab Runners, use Galileo for model evaluation and observability, and collaborate across teams to deliver production-grade autonomous systems.
Top Skills: Agentic FrameworksFastapiGalileoGitlab RunnersJenkinsPythonPyvegas
Reposted 3 Days AgoSaved
Remote
Des Moines, IA
154K-226K Annually
Senior level
154K-226K Annually
Senior level
Financial Services
Lead design, build, and production deployment of ML and GenAI solutions (LLMs, RAG, multi-agent systems, recommender and RL models). Architect scalable, secure inference and MLOps pipelines, mentor MLEs, collaborate with stakeholders to define roadmaps, and measure model performance and business impact. Implement fine-tuning, retrieval, orchestration, and monitoring for enterprise-grade AI products.
Top Skills: Apache AirflowCausal Meta-LearnerDatabricksDatabricks MlflowDatabricks Model ServingDeep LearningDvcFlinkGraph Neural NetworksGraphQLGrpcHugging Face TransformersKafkaKinesisKubeflowLangchainLarge Language Models (Llms)LlamaindexLoraPeftPyTorchQloraRayReinforcement LearningRetrieval Augmented Generation (Rag)SnowflakeSparkTensorFlowTransformersXgboost
Reposted 3 Days AgoSaved
Remote
Des Moines, IA
131K-246K Annually
Senior level
131K-246K Annually
Senior level
Artificial Intelligence • Software
The role involves managing the ML lifecycle, developing scalable ML systems, and collaborating on AI-first product solutions focusing on Large Quantitative Models.
Top Skills: AWSGCPJaxNumpyPandasPythonPyTorchTensorFlow
Reposted 3 Days AgoSaved
Remote
Des Moines, IA
238K-288K Annually
Senior level
238K-288K Annually
Senior level
HR Tech • Software
The role involves owning and delivering AI-powered features for Calendly, collaborating with multiple teams, and applying machine learning solutions for product enhancement.
Top Skills: JavaPythonScalaSQL
Reposted 3 Days AgoSaved
Remote
Des Moines, IA
160K-310K Annually
Senior level
160K-310K Annually
Senior level
Information Technology • Consulting
The Senior Vice President will lead projects focused on corporate performance, drive revenue growth, and develop business strategies while utilizing data modeling and machine learning techniques for analysis and solutions.
Top Skills: AWSAzureC#Datastage)Etl Tools (AlteryxGCPJavaScriptKnimePentahoPower BIPythonRSQLSsisTableau
Reposted 4 Days AgoSaved
Remote or Hybrid
Des Moines, IA
180K-250K Annually
Senior level
180K-250K Annually
Senior level
Artificial Intelligence • Professional Services • Consulting • Automation
Design and deploy production recommendation and retrieval engines, build data orchestration pipelines for multiple modalities, implement agentic workflow frameworks, and prototype, optimize, and scale models with monitoring, governance, and low-latency SLAs.
Top Skills: AirflowSparkEmbeddingsKafkaKubernetesLangchainPythonPyTorchRagRetrieval LibrariesServerlessTensorFlowTransformer-Based Models
Reposted 5 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Gaming
The DevOps Engineer will design, build, and optimize ML and data infrastructure on GCP, mentor a team, and ensure system reliability and performance.
Top Skills: AnsibleBigQueryBigtableCloud RunComposerDatadogDataflowDockerGoogle Cloud Platform (Gcp)GroovyJenkinsKubernetesPub/SubPythonShellTerraformVertex Ai
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Reposted 5 Days AgoSaved
Remote
Des Moines, IA
151K-179K Annually
Senior level
151K-179K Annually
Senior level
Other
Lead and mentor engineering teams while owning platform architecture (React, Node/Express, Postgres, AWS). Drive TypeScript migration, design ETL and AI/LLM integration frameworks, ensure reliability and observability, manage delivery, incidents, and hiring, and define technical strategy for production ML/AI systems.
Top Skills: Aws EcsAws LambdaAws RdsAws S3ETLEvent-Driven ArchitectureExpressJavaScriptLlmMessage QueuesMl/AiNode.jsPostgresReactStreaming PipelinesTypescript
Reposted 5 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Healthtech • Software • Biotech
Lead design, development, and production deployment of ML models and GenAI/LLM solutions to optimize clinical trial workflows. Build scalable pipelines, monitoring, and CI/CD for robust production use. Collaborate cross-functionally, mentor junior engineers, and communicate technical results to technical and non-technical stakeholders.
Top Skills: Ci/CdCloud InfrastructureFine-TuningGenaiLarge Language Models (Llms)Ml PipelinesModel DeploymentModel MonitoringPythonSQL
Reposted 6 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Software
The Senior Data Engineer will own the data strategy, managing sourcing, structuring, and optimizing multimodal data to enhance AI models and products.
Top Skills: Large-Scale Data ProcessingPythonSQL
Reposted 6 Days AgoSaved
Remote
Des Moines, IA
220K-260K Annually
Senior level
220K-260K Annually
Senior level
Artificial Intelligence • Marketing Tech • Mobile • Software
As a Senior Software Engineer, you'll build and operate the ML platform, optimizing data operations, managing the feature store, and supporting ML initiatives while driving architectural roadmap decisions.
Top Skills: AirflowSparkAWSCloudflareDynamoDBGradleGraphQLHuggingfaceJavaKafkaKinesisKubernetesMetaflowPandasPlanetscalePlaywrightPostgresPythonPyTorchRayReactRedisSpark Structured StreamingSpring BootTensorFlowTerraformTypescriptVite
Reposted 6 Days AgoSaved
Remote
Des Moines, IA
260K-310K Annually
Senior level
260K-310K Annually
Senior level
Artificial Intelligence • Marketing Tech • Mobile • Software
The Staff Engineer will architect and build AI and ML infrastructures, mentor engineers, and lead high-impact initiatives to enhance ML capabilities across Attentive's platform.
Top Skills: ArgoKubeflowMetaflowMlflowPythonRaySpark
Reposted 6 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Information Technology
The Machine Learning Solutions Architect designs and implements data solutions, overseeing model deployment and ensuring robust performance and integration within customer environments.
Top Skills: AWSAzureDatabricksDjangoFlaskGCPJavaPythonScalaSnowflakeSparkSQL
7 Days AgoSaved
Remote
Des Moines, IA
158K-170K Annually
Senior level
158K-170K Annually
Senior level
Financial Services
Lead development and deployment of predictive and ML models for credit risk, collections, and operations. Mentor data scientists, promote MLOps and modern tools, present insights to stakeholders, and drive experimentation with techniques such as causal inference and GenAI.
Top Skills: Causal InferenceDeep LearningEnsemble ModelsExplainabilityGenerative AiMlopsModel GovernanceNlpPythonRResponsible AiSASSQL
7 Days AgoSaved
Remote
Des Moines, IA
97K-165K Annually
Senior level
97K-165K Annually
Senior level
Financial Services
Design, develop, implement, and monitor statistical and machine learning models to support credit risk, collections, servicing, marketing, and forecasting. Build data pipelines, translate business needs into analytical solutions, support model governance, testing, deployment, and ongoing performance monitoring, and communicate results to stakeholders.
Top Skills: PythonRSASSQL
Reposted 7 Days AgoSaved
In-Office or Remote
Des Moines, IA
111K-222K Annually
Senior level
111K-222K Annually
Senior level
Fitness • Healthtech • Retail • Pharmaceutical
The Senior Machine Learning Engineer will build and optimize ML systems for CRM marketing, collaborating with cross-functional teams to impact customer engagement and product functionality.
Top Skills: AirflowBigQueryKafkaKubeflowNode.jsPythonPyTorchReactSnowflakeSparkSQLTensorFlowVertex
7 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Artificial Intelligence • Machine Learning
Partner with customers to design and deliver production-ready AI/ML solutions, drive POC-to-production success, troubleshoot technical issues, inform product roadmap with customer feedback, and communicate outcomes to stakeholders.
Top Skills: Agent FrameworksAWSAzureGCPKubernetesLlmsMlopsPythonVector Dbs
Reposted 7 Days AgoSaved
Remote
Des Moines, IA
141K-195K Annually
Senior level
141K-195K Annually
Senior level
Database • Analytics
Develop AI/ML-powered features in ClickHouse Cloud, focusing on frontend and API architecture, UI/UX, and integrations with AI systems.
Top Skills: AWSAzureClickhouseGCPJavaScriptPythonReactTypescript
Reposted 7 Days AgoSaved
Remote
Des Moines, IA
Senior level
Senior level
Healthtech • Software • Database • Biotech • Pharmaceutical
As a Senior Machine Learning Engineer, you will develop and deploy AI-driven products to enhance clinical trials, collaborating with teams to improve patient care through scalable machine learning solutions.
Top Skills: AthenaAWSBedrockCi/CdClojureDbtPandasPrefectPythonPyTorchSagemakerScikit-LearnTensorFlow
Reposted 8 Days AgoSaved
Remote
Des Moines, IA
210K-275K Annually
Senior level
210K-275K Annually
Senior level
Healthtech • Information Technology • Software • Consulting
The Director of AI & ML is responsible for establishing and leading the AI function, defining AI strategy, building a high-performing team, and delivering production-grade ML and AI solutions within healthcare payer workflows.
Top Skills: AIAWSGenerative AiHuggingfaceLlmMlMlopsPythonPyTorchTensorFlow
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