About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job DescriptionWe are seeking an enthusiastic and creative hands-on senior scientist to join the Cell Culture Process Development group within PDS&T Biologics at AbbVie Bioresearch Center in Worcester, MA. As part of the Cell Culture Development organization, you will support process development and technology transfer activities for cell culture processes, contributing to the clinical manufacturing and commercialization of therapeutic proteins in the AbbVie pipeline. Additionally, you will be a part of a team that provides subject matter expertise and experimental support for the production of commercial biologics. The ideal candidate will work effectively both independently and collaboratively within a dynamic team environment.
Key Responsibilities:
- Develop and characterize highly-productive CHO cell culture processes suitable for cGMP biotherapeutic manufacturing within project timelines, performing technical transfer, and manufacturing support activities.
- Lead and execute scientific research and development initiatives to reduce cost of goods (COGs) by significantly improving platform processes and workflows, deepening scientific understanding, and applying new methods and technologies. These include cell metabolic modeling, perfusion technology, and a suite of Process Analytical Technology (PAT) tools.
- Design, execute, and analyze cell culture experiments using Design of Experiments (DOE) principles and report data summary packages for multi-variate analysis.
- Work collaboratively and cross-functionally with colleagues in other functional areas (Analytical Development, Cell Line Development, Discovery, Manufacturing, and Quality). Effectively communicate scientific data and concepts to internal and external audiences through reports, presentations and manuscripts. Author and review technical reports, protocols, and other key documents.
- Understand and adhere to corporate standards regarding code of conduct, safety, documentation and GMP compliance.
- Bachelor’s Degree or equivalent education with minimum 10 years of experience, or Master’s Degree or equivalent education with minimum 8 years of experience. Or PhD with no minimum years of experience, in chemical engineering, biochemical engineering, or a related discipline.
- Proven ability to independently design experiments, troubleshoot technical issues, and deliver high-quality scientific output.
- Strong understanding of cell biology with extensive hands-on experience with mammalian suspension cell culture
- Theoretical and practical knowledge to carry out the job functions.
Preferred Qualifications:
- Understanding of cell culture processes (e.g., cell culture process development, process scale up and scale down, recombinant protein production, protein characterization).
- Demonstrated experience in cell metabolic modeling and process modeling using mechanistic model and/or machine learning algorithms.
- Familiarity with bioreactor perfusion processes.
- Demonstrated experience in applying Process Analytical Technology (PAT) to improve cell culture processes.
- Hands-on experience with upstream mammalian suspension cell culture using bench scale bioreactors, AMBR, and shake flasks.
- Excellent interpersonal and communication skills. Strong scientific curiosity with a passion for problem-solving and optimization. Self-motivated with excellent attention to detail and ability to multi-task. Strong organizational, planning and trouble-shooting skills.
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount isearned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that areallocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolutediscretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Skills Required
- Bachelor's degree with minimum 10 years, Master's with minimum 8 years, or PhD (no minimum) in chemical, biochemical engineering or related discipline
- Proven ability to independently design experiments and troubleshoot technical issues
- Extensive hands-on experience with mammalian suspension cell culture (CHO)
- Working knowledge and adherence to cGMP and GMP documentation/safety requirements
- Experience using Design of Experiments (DOE) and multi-variate analysis
- Strong understanding of cell biology and theoretical/practical knowledge to perform job functions
- Experience with cell metabolic modeling and process modeling using mechanistic models and/or machine learning algorithms
- Familiarity with bioreactor perfusion processes
- Experience applying Process Analytical Technology (PAT) to upstream processes
- Hands-on experience with bench-scale bioreactors, AMBR, and shake flasks
- Experience with recombinant protein production and protein characterization
- Excellent interpersonal and communication skills; ability to author and present technical reports
AbbVie Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about AbbVie and has not been reviewed or approved by AbbVie.
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Retirement Support — 401(k) contributions include a dollar-for-dollar match up to 6% plus an additional annual company contribution tied to age and service. Company-paid life insurance and other financial protections further strengthen long-term security.
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Parental & Family Support — Paid leave programs include up to 12 weeks at 100% for parental leave and separate paid caregiver leave, with eligibility after six months where noted. Adoption and surrogacy reimbursements and family-building resources add further support.
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Healthcare Strength — Health coverage begins on day one with medical, dental, vision, mental health, and prescription benefits, and preventive care covered at 100%. Options such as HSAs/FSAs and coverage for spouses/domestic partners and children up to age 26 broaden accessibility.
AbbVie Insights
What We Do
AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first — for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuroscience, eye care, aesthetics and other areas of unmet need.
