GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured.
The Role
Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.
GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
For more information, please visit grail.com
As a Senior Software Product Manager, you will play a key role in defining priorities and requirements to continue to evolve our software platform leveraged for getting samples into the lab and results out to patients. This set of software capabilities drives a core of GRAIL’s business - converting specimens into insights which power improved patient outcomes.
This is a hybrid role based in either Menlo Park, CA (moving to Sunnyvale, CA in Fall 2026) or Durham, NC. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site.
Responsibilities
- Develop and deliver on product roadmaps for GRAIL’s sample receipt, accessioning, and report review software platform, based on a deep understanding of user needs and business goals
- Build alignment among stakeholders and collaborating teams (Operations, Billing, Commercial, Software Engineering, Medical Affairs, Quality, etc.)
- Partner closely with Software Engineering, Program Management, and the Test Team to drive prioritization, execution, and delivery of high impact features and functionality based on business value and user needs
- Remove bottlenecks that directly impact our anti-cancer mission
- Write product and software requirements to guide software development
- Create and maintain processes for collecting and prioritizing feedback and requests from users
- Partner with Regulatory and Quality teams to support risk assessments, audits and software validation
These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.
Required Qualifications
- 5+ years of experience in software product management
- BA/BS, Graduate degree, or equivalent work experience in life or physical sciences, engineering or computer science or equivalent
- Experience working with regulated products
- Excellent strategic, analytical, communication and presentation abilities.
- Demonstrated ability to: independently navigate and lead through ambiguity; guide without authority; negotiate scope, product features, and specifications with stakeholders and the development team
- Ability to ruthlessly prioritize, set goals and deliver results with an emphasis on quality, technical planning, and attention to detail
- Experience working in a fast-paced environment, leading complex strategic and operational initiatives, working through technical, operational, legal/regulatory, and business issues.
- Ability to prioritize, set goals and deliver results with a high emphasis on quality, technical planning, and attention to detail.
Preferred Qualifications
- Experience in the development or utilization of software to support lab processes, workflow automation, or other high volume manufacturing processes is highly preferred
- Experience in healthcare, life sciences, diagnostics, or other regulated industries is highly preferred
- Experience working with AI tools is preferred
The expected, full-time, annual base pay scale for this position is $136K-$180K.
This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.
GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.
GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!
What the Team is Saying
Neda Ronaghi
Strategy and Operational Excellence Associate Director
Ruth Mauntz
Staff Bioinformatics Scientist
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Tristan Matthews
Senior Director, Software Engineering
David Jenions
Principal Automation Engineer
Satnam Alag
SVP, Software Engineering
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GRAIL Compensation & Benefits Highlights
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Healthcare Strength — Comprehensive medical, dental, and vision coverage is paired with mental‑health resources and disability insurance, with some roles noting strong employer support for HSAs on high‑deductible plans.
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Equity Value & Accessibility — New‑hire equity grants with clear vesting schedules and an active ESPP make ownership a meaningful part of total rewards, with equity described as straightforward and accessible.
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Leave & Time Off Breadth — Flexible time off policies, paid holidays, and routine company breaks (e.g., summer and winter) are highlighted across locations, with additional generous vacation allowances in the UK.
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The Company
What We Do
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is using the power of high-intensity sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop and commercialize pioneering products.
Why Work With Us
Everything we do is guided by our mission to detect cancer early, when it can be cured. It’s the reason we’re here, and it’s no small task. The right people make all the difference. That’s why we’re looking for those who strive to share their knowledge, contribute their skills, inspire each other and commit to something bigger than themselves.
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GRAIL Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
GRAIL has a variety of work types depending on the roles. Some roles are onsite like a lab role, some are fully remote like our Galleri Sales Consultant roles. Others are hybrid with 2-3 days onsite. Typically Tuesday and Thursday.
Typical time on-site:
2 days a week
