The Equipment Engineer 2 provides professional engineering support in the evaluation, installation, optimization, and maintenance of manufacturing equipment and automation systems. Operating with increasing independence, this role applies engineering principles to analyze equipment performance, resolve technical issues, and contribute to improvements that enhance reliability, efficiency, and compliance. The position partners with cross-functional teams to implement engineering solutions, maintain accurate technical documentation, and ensure equipment systems operate effectively within defined standards and operational goals.
You will work on-site full-time at our office located in Durham, NC
Responsibilities:
Conducts professional engineering analyses to assess equipment performance, identify reliability concerns, and develop data-driven recommendations for improvement.
Supports the installation, modification, and qualification of laboratory manufacturing equipment by applying engineering principles and collaborating with technicians, engineers, and operations teams.
Executes advanced maintenance, repair, and technical adjustments on complex manufacturing equipment by applying extensive procedural knowledge and hands-on expertise
Applies structured problem-solving methods to troubleshoot equipment issues, develop corrective actions, and implement improvements that strengthen equipment reliability.
Develops, updates, and maintains engineering documentation, including technical specifications, process instructions, test results, and change records, in accordance with engineering controls.
Collaborates with cross-functional partners on continuous improvement initiatives, contributing engineering insights that enhance equipment capability, throughput, and performance.
Supports preventive and predictive maintenance programs by evaluating equipment behavior, reviewing failure data, and recommending engineering-driven reliability enhancements.
Performs engineering-level testing, calibration, and verification activities to ensure equipment accuracy and compliance with quality and safety standards.
Exercises professional judgment within established engineering practices to ensure safe, compliant, and efficient operation of manufacturing equipment.
- These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.
Required Qualifications:
Bachelor’s degree in mechanical engineering, electrical engineering, manufacturing engineering, or related discipline.
2 + years of relevant experience in equipment engineering, manufacturing, or maintenance engineering, or a master’s degree with 0–2 years of experience.
Demonstrated knowledge of automated manufacturing systems, control systems, and process instrumentation.
Proficiency in reading and interpreting mechanical and electrical drawings and schematics.
Familiarity with root cause analysis and failure mode and effects analysis (FMEA) tools.
Demonstrated level of knowledge regarding applicable regulatory standards commensurate with the position's complexity and scope, contributing to organizational regulatory compliance. Minimal applicable standards for this position include:
GMP quality management systems (e.g. ISO 13485)
Clinical laboratory regulations (e.g. CAP, CLIA, NYSDOH, ISO 15189)
Operations within the regulated medical device environment (e.g. IVDD, IVDR, FDA 21 CFR 800 series, FDA 21 CFR Part 11)
Preferred Qualifications:
Strong problem-solving skills with the ability to diagnose complex equipment and process issues.
Analytical and data-driven approach to process improvement and decision-making.
Effective collaboration and communication skills across technical and operational teams.
Ability to manage multiple assignments and adapt to changing priorities in a fast-paced environment.
Commitment to quality, safety, and operational excellence.
Physical Demands and Work Environment
Works in a manufacturing and engineering environment with frequent exposure to production equipment, machinery, and moderate noise.
May require hands-on support in production areas, including standing, bending, or lifting equipment components.
Use of personal protective equipment (PPE) is required per safety and compliance standards.
May occasionally require overtime or off-shift support to address critical maintenance or project activities.
Skills Required
- Bachelor's degree in mechanical engineering, electrical engineering, manufacturing engineering, or related discipline
- 2 + years of relevant experience in equipment engineering, manufacturing, or maintenance engineering, or a master's degree with 0-2 years of experience
- Demonstrated knowledge of automated manufacturing systems, control systems, and process instrumentation
- Proficiency in reading and interpreting mechanical and electrical drawings and schematics
- Familiarity with root cause analysis and failure mode and effects analysis (FMEA) tools
- Knowledge of applicable regulatory standards commensurate with the position's complexity and scope
What the Team is Saying
.JPG)
.JPG)
GRAIL Compensation & Benefits Highlights
-
Healthcare Strength — Comprehensive medical, dental, and vision coverage is paired with mental‑health resources and disability insurance, with some roles noting strong employer support for HSAs on high‑deductible plans.
-
Equity Value & Accessibility — New‑hire equity grants with clear vesting schedules and an active ESPP make ownership a meaningful part of total rewards, with equity described as straightforward and accessible.
-
Leave & Time Off Breadth — Flexible time off policies, paid holidays, and routine company breaks (e.g., summer and winter) are highlighted across locations, with additional generous vacation allowances in the UK.
GRAIL Insights
What We Do
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is using the power of high-intensity sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop and commercialize pioneering products.
Why Work With Us
Everything we do is guided by our mission to detect cancer early, when it can be cured. It’s the reason we’re here, and it’s no small task. The right people make all the difference. That’s why we’re looking for those who strive to share their knowledge, contribute their skills, inspire each other and commit to something bigger than themselves.
Gallery
GRAIL Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
GRAIL has a variety of work types depending on the roles. Some roles are onsite like a lab role, some are fully remote like our Galleri Sales Consultant roles. Others are hybrid with 2-3 days onsite. Typically Tuesday and Thursday.
.png)
