We are seeking an experienced and strategic Principal Security Architect to lead the design, implementation, and oversight of enterprise-class network and cloud security across our global infrastructure. This role blends deep technical expertise with strategic leadership and focuses on securing our on-premises data centers, public cloud platforms, and enterprise network edge using best-in-class tools like Palo Alto and Cisco.
This is a hands-on leadership role that influences global security architecture, mentors’ engineers, and collaborates with cross-functional teams to protect our digital assets at scale.
Key Responsibilities
Security Architecture & Engineering
- Lead the design and evolution of security controls across hybrid cloud and on-prem environments.
- Architect and implement network segmentation, next-gen firewall policies, and zero-trust access models.
- Define secure connectivity strategies across WAN, remote access, data centers, and cloud networks.
Technology Ownership
- Serve as SME for Palo Alto Networks firewalls, Prisma Access, and Panorama.
- Lead security configuration, lifecycle management, and policy enforcement on Cisco security platforms (ASA, ISE, Firepower, Umbrella).
- Harden security for multi-cloud platforms (AWS, Azure, GCP) including IAM, VPCs, firewalls, and API security.
Operations & Response
- Lead threat detection and response for network and infrastructure incidents.
- Collaborate with SOC, GRC, and infrastructure teams to close security gaps and maintain compliance.
- Continuously improve security monitoring, alerting, and forensics capabilities.
Security Automation & Tooling
- Integrate security into CI/CD pipelines and infrastructure provisioning via Terraform, Ansible, or Python.
- Automate security posture checks and drift detection in public cloud and data center environments.
- Work with vulnerability management platforms and integrate findings into remediation workflows.
Governance, Risk & Compliance
- Define security baselines and configuration standards for networking and infrastructure teams.
- Ensure compliance with frameworks such as ISO 27001, NIST, CIS, and industry-specific requirements.
- Participate in audits, risk assessments, and security reviews for new technologies and vendors.
Required Qualifications
- 10+ years of experience in infrastructure or network security, with 3+ years in a principal or lead role.
- Deep expertise in Palo Alto Networks products and Cisco security platforms.
- Strong understanding of cloud security architecture and native security tools in AWS, Azure, and/or GCP.
- Experience securing on-premise and hybrid data centers, including virtualization and SDN technologies.
- Proven experience designing and enforcing enterprise security policies across global networks.
- Solid knowledge of routing/switching protocols (BGP, OSPF), VPNs, DNS security, and NAC.
- Familiarity with SIEM, NDR, and EDR tools for detection and response.
- Scripting/automation proficiency (Python, Bash, PowerShell, or IaC tools).
Preferred Qualifications
- Certifications such as PCNSE, CISSP, CCNP Security, AWS/Azure Security Specialty.
- Experience with identity federation (SAML, OAuth), secrets management, and PKI.
- Background in segmentation frameworks (e.g., SCADA/ICS, OT security), or data loss prevention (DLP).
- Experience in DevSecOps or cloud-native security tooling.
We are an equal-opportunity employer and do not discriminate because of race, color, religion, sex, national origin, ancestry, marital status, veteran status, age, disability, sexual orientation or gender identity or expression or any other legally protected category. InterSystems is an E-Verify Employer in the United States.
InterSystems is providing a current good faith estimate of the anticipated base salary range for this position depending on a variety of factors including experience, education, skills, and performance.
Other compensation may include a discretionary annual variable target incentive.
The company also provides generous employee benefits including:
- Medical, vision, and dental insurance
- Short-term and long-term disability, and life insurance
- 401(k) Profit Sharing Contribution
- Paid Time Off and Holidays
- Parental Leave
- Tuition reimbursement
About InterSystems
InterSystems, a creative data technology provider, delivers a unified foundation for next-generation applications for healthcare, finance, manufacturing, and supply chain customers in more than 80 countries. Our data platforms solve interoperability, speed, and scalability problems for large organizations around the globe to unlock the power of data and allow people to perceive data in imaginative ways. Established in 1978, InterSystems is committed to excellence through its 24×7 support for customers and partners around the world. Privately held and headquartered in Boston, Massachusetts, InterSystems has 38 offices in 28 countries worldwide. For more information, please visit InterSystems.com.
Top Skills
What We Do
InterSystems builds the software that makes complex systems work—reliably, securely, and at scale. For more than 45 years, we’ve been the information engine behind some of the world’s most mission-critical applications in healthcare, government, and business.
Our data management, integration, and analytics technologies help organizations connect disparate systems, turn data into insight, and deliver better outcomes. From enabling interoperable healthcare and advancing clinical care, to powering national infrastructure and large-scale enterprise systems, our technology is used every day by millions of people in more than 80 countries.
What sets InterSystems apart is not just what we build, but how we build it. We focus on long-term innovation, deep engineering excellence, and solving hard problems that truly matter. Our teams work closely with customers to tackle real-world challenges—often behind the scenes, but always at the heart of what keeps essential systems running.
If you’re motivated by meaningful work, technical depth, and the opportunity to have a global impact, you’ll find it here.
Why Work With Us
Because we are a profitable, privately-held software company, we place our clients first in everything we do. You’ll work on meaningful, complex problems alongside deeply curious experts in a culture that values learning, ownership, and long-term growth—without the pressure of quarterly Wall Street demands.
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InterSystems Teams
InterSystems Offices
OnSite Workspace
For the first 3 or 6 months (experience and role dependent), we ask our employees to work in the office 5 days a week. After that time, our employees receive 24 work from home Fridays to use at their discretion throughout the year.






