Jobs at ICON plc

Design, develop and deploy machine learning models and advanced data analyses on large healthcare datasets. Collaborate with cross-functional teams to translate business needs into analytical solutions, mentor colleagues, drive process improvement and operational excellence, and communicate insights through visualization and reporting to inform decision-making.

Lead clinical trial monitoring and site oversight to ensure protocol, regulatory and GCP compliance. Conduct site visits, resolve issues, support data integrity and reporting, train and guide site staff and CRAs, collaborate cross-functionally, and manage multiple sites for successful trial execution.

Lead and perform clinical trial monitoring to ensure protocol compliance, GCP adherence, and data integrity. Conduct site visits, resolve issues, train site staff and junior CRAs, collaborate with cross-functional teams, manage multiple sites, and maintain stakeholder relationships to support successful trial execution. Frequent travel required.

Designs and contributes to clinical trial protocols and study documents, supports regulatory and pharmacovigilance activities, performs in-depth clinical data review and trend analysis, guides CRF and data capture strategy, delivers training, and collaborates with clinical development leads to ensure data integrity and patient safety across global oncology studies.

Lead and implement risk-based site monitoring strategies, configure monitoring in systems, manage site monitoring assignments and training, review visit reports, monitor compliance KPIs, support RBQM operations, and provide oversight and documentation for site monitoring activities across the study.

Lead strategic planning and execution of complex, multi-site clinical trials. Manage clinical operations teams, CROs and vendors, ensure ICH-GCP and regulatory compliance, oversee budgeting, recruitment, site performance, submissions, and cross-functional collaboration to meet timelines and quality standards.

Provide corporate governance and company secretarial support for ICON's global and LATAM entities, focusing on Mexico. Prepare filings, board materials, resolutions, powers of attorney; maintain corporate records and entity database; liaise with notaries, embassies, auditors and external advisors; support restructurings and ad hoc legal projects.

Lead local end-to-end trial management for solid tumor oncology studies, act as primary site contact, ensure recruitment and data quality, manage site selection/startup, vendor and budget oversight, ensure compliance with ICH-GCP and regulations, maintain trial systems (CTMS/eTMF), support inspections, and drive corrective actions and site engagement to meet timelines and targets.

The Clinical Site Associate supports clinical trial operations, manages site communications, maintains documentation, and ensures compliance for site readiness.

Lead clinical data management and analysis for trials, ensure data accuracy and regulatory compliance, design data strategies, oversee collection/validation, create analysis plans and reports, and manage and mentor data teams to improve processes.

Lead development and validation of LC/MS/MS assays for preclinical and clinical specimens; oversee method transfers, ensure assay quality, review data, support lab operations, consult with sponsors, and publish/present scientific findings.

Support clinical data management activities including eCRF and data validation development, review and query resolution, third-party data review, and study documentation to meet timelines and maintain data quality.

Support implementation and use of ADaM and define.xml within the Medidata standard, develop tools and metrics to improve data collection, tabulation, analysis and reporting, configure metadata repositories for CDISC metadata, mentor consultants, lead SME teams, consult with sponsors, and drive standards-related process improvements.

Perform site qualification, initiation, monitoring, and close-out visits for clinical trials; ensure protocol compliance, data integrity, and patient safety; collaborate with investigators and site staff; review data and resolve queries; contribute to study documentation including protocols and clinical study reports.

Edit and proofread scientific and regulatory documents for clinical trials, ensure accuracy and compliance, mentor junior staff, perform fact-checking, collaborate with medical writers, implement SOPs, and stay current with medical writing standards.

Lead clinical project delivery for oncology radiopharmaceutical and radioligand programs: develop and execute project plans, manage cross-functional teams, mentor staff, define scope, produce documentation and stakeholder reports, integrate industry best practices, and support organizational growth. Approximately 25% travel.

Support FP&A through variance analysis, forecasting, budgeting, and complex financial modeling. Prepare monthly/quarterly/annual reports, monitor financial and operational metrics, recommend process improvements, and collaborate cross-functionally to support strategic decision-making.

Lead clinical project planning and execution for pharmaceutical and radiopharmaceutical programs. Manage cross-functional teams, define scope, mentor staff, produce project documentation and reports, integrate industry best practices, and support organizational growth. Ensure delivery of project objectives while managing competing priorities and specialized operational requirements in oncology and radioligand studies.

Lead and manage pharmaceutical/biotech projects: develop and execute plans, lead cross-functional teams, define scope, mentor staff, produce documentation and reports, integrate best practices, and drive strategic project delivery.

Lead coordination and oversight of clinical trial activities to ensure protocol adherence, regulatory compliance, site management, data integrity, risk identification, and cross-functional collaboration to support study execution and continuous improvement.