Jobs at AstraZeneca

Leads global late-stage clinical development programs in immunology and gastroenterology for clinical-stage therapies. Responsibilities include study design, clinical development planning, protocol and regulatory document development, medical monitoring, safety surveillance, investigator engagement, regulatory responses, risk mitigation, clinical study reporting, publication strategy, and leadership of global study teams and project physicians.

Design, validate, and deploy publication-grade predictive and causal models for commercial and patient outcomes in rare disease. Build survival and time-series models, Bayesian marketing-mix and next-best-action systems, integrate Snowflake Cortex AI and AI agents, ensure HIPAA-compliant data operations, implement interpretability and bias guardrails, and translate insights to commercial stakeholders.

Develop and optimize integrated laboratory automation platforms for high-throughput antibody expression, purification, and characterization. The role combines hands-on bench science with automation engineering, including robotic method development, workflow troubleshooting, and process scaling. The scientist will support molecular and cell biology workflows, collaborate with scientists, data engineers, software developers, and global automation teams, and serve as an on-site automation expert. Responsibilities also include translating scientific processes into reliable automated solutions and expanding laboratory automation capabilities.

Provides executive and administrative support to senior HR leaders, including calendar, travel, expenses, meetings, communications, and follow-up. Coordinates events, projects, trackers, and operational activities across global teams. Prepares reports, analyzes HR and business data, develops leadership materials, and supports decision-making. Improves workflows using digital tools, automation, and AI while maintaining confidentiality, data privacy, accuracy, and strong stakeholder relationships.

Lead integrated clinical development for myositis/immunology and autoimmune programs, designing and executing scientifically rigorous, commercially viable trials. Oversee study protocol, feasibility, timelines, CRO/vendor selection, regulatory submissions, cross-functional coordination, team leadership and mentoring, and ensure compliance and delivery across global development lifecycle.

Manages externally sponsored research studies in the USA for oncology programs, serving as the operational liaison among sponsors, franchise teams, finance, regulatory, and research sites. Responsibilities include proposal triage, governance coordination, contracts, budgets, system maintenance, compliance, risk mitigation, corrective action plans, payments, and inspection readiness. The role requires pharmaceutical study management experience, knowledge of clinical development and GCP/ICH guidelines, financial expertise, and strong stakeholder-management skills.

Leads and coaches a regional Clinical Trial Liaison team supporting investigator and research-site engagement across US clinical trials. Translates national priorities into regional field plans, improves trial start-up, enrollment, and retention, and coordinates with Clinical Operations, Site Management, Medical Affairs, MSLs, and other partners. The role manages talent, performance, resources, travel, compliance, and field insights while driving execution, change adoption, and scientific engagement across AstraZeneca’s clinical pipeline.

Leads AstraZeneca’s U.S. rare neurology sales organization across gMG, NMOSD, and emerging indications. Oversees multi-level sales leadership, national and regional execution, launches, forecasting, market access partnerships, KOL and advocacy engagement, and commercial performance. Drives AI-enabled targeting, analytics, customer engagement, and operational excellence while building a high-performing, compliant, patient-centric organization. Requires extensive specialty and rare disease pharmaceutical sales leadership, biologics commercialization, launch experience, and regular nationwide travel.

Supports finance operations for manufacturing and quality sites through month-end close, journal entries, variance analysis, forecasting, budgeting, inventory and capital expenditure accounting, financial reporting, audit support, and process improvement. The role partners with site Finance and senior management, maintains reporting accuracy and controls, coordinates planning deliverables, supports financial analysts, documents processes, and helps implement finance tools and transformation initiatives.

Conducts clinical selling and educates healthcare professionals on breast oncology treatments, including efficacy, safety, dosing, approved indications, and companion diagnostics. Develops tumor-focused account and engagement plans, assesses patient-journey opportunities, identifies multidisciplinary stakeholders, collaborates with oncology field teams, and contributes to geographic business priorities. Builds healthcare-provider relationships through in-person and virtual channels while supporting patient identification and improved care.

Leads study-level clinical science across neuroimmunology trials, owning protocol and clinical document development, medical and data review, endpoint integrity, safety surveillance, data cleaning, regulatory support, and scientific disclosures. Partners with Study Physicians, clinical operations, pharmacovigilance, data management, biostatistics, sites, and CROs. Supports inspection-ready execution, clinical data interpretation, governance readouts, and mentorship of junior clinical scientists.

Leads global oncology regulatory strategy across drug portfolios, guiding approval and launch pathways for small molecules and biologics. Oversees regulatory leaders, portfolio strategy, submission quality, regulatory intelligence, digital transformation, external health-authority engagement, business development diligence, budgets, talent development, and governance influence. Requires substantial executive-level regulatory experience, oncology expertise, global drug-development knowledge, successful approvals, and strong people and portfolio leadership.

Leads global clinical development strategy and execution for hematology drug programs. Provides scientific input on trial design, protocols, data review, interpretation, clinical study reports, regulatory submissions, and product registration. Collaborates with clinical operations, medical directors, regulatory bodies, investigators, and external providers. Ensures compliance with GCP, ICH, regulations, and internal quality standards while leading cross-functional development projects and investigator training.

Analyzes and triages demand for digital HR products supporting Talent Acquisition and Talent Management. Translates user needs into requirements, user stories, acceptance criteria, and prioritized backlogs; assesses impact, dependencies, privacy, security, and risks. Coordinates stakeholder collaboration, vendor evaluation, user acceptance testing, defect management, release readiness, and product-support governance across global HR technology platforms.

Leads manufacturing operations and a multidisciplinary Process Execution Team at a pharmaceutical site. Oversees production, materials, assets, inventory, supply chain performance, budgets, staffing, and transformational change. Ensures compliance with cGMP, SHE, SOX, licenses, and business procedures while maintaining capacity to meet demand. Drives Lean practices, stakeholder engagement, strategic decision-making, and continuous improvement across regional operations.

Manage strategic healthcare accounts across Sofia and the surrounding region for AstraZeneca’s rare disease portfolio. Build relationships with physicians, pharmacists, nurses, hospitals, clinics, and other decision-makers; develop account plans; generate compliant demand; communicate scientific and value-based information; share market insights; and coordinate with sales, marketing, and medical teams. The role requires territory planning, ethical engagement, regulatory compliance, product knowledge, and travel within the assigned territory.

Supports the implementation and maintenance of Alexion’s pharmaceutical compliance program in France and BeLux. Responsibilities include monitoring, audit and investigation support, risk framework administration, compliance education programs, approval processes, documentation management, business information analysis, and initiative tracking through metrics and scorecards. The role requires pharmaceutical compliance knowledge, strong communication and analytical skills, project management experience, discretion, ethical judgment, and proficiency with company administrative tools.

Designs and executes in vitro and in vivo pharmacology studies for lentiviral cell and gene therapy candidates. Develops and qualifies assays for potency, mechanism of action, and developability; oversees humanized mouse studies and CROs; integrates data to support IND-enabling decisions; authors nonclinical reports and regulatory submission sections; and presents findings to internal and external stakeholders while maintaining rigorous documentation.

Leads global early-asset forecasting, commercial market insights, and business-development investment analysis across respiratory and immunology portfolios. Builds patient-based models, scenarios, and risk-adjusted forecasts; supports licensing, partnerships, and acquisitions; advises executives on portfolio and deal decisions; oversees market research; and advances responsible AI, automation, and model governance.

Leads global and regional regulatory submissions, health authority interactions, product registrations, lifecycle management, and post-marketing activities. Advises senior stakeholders on regulatory strategy, compliance, risks, and timelines while driving submission quality and process improvements. Partners with cross-functional and external teams, maintains regulatory records, implements new regulatory systems, monitors evolving requirements, and mentors colleagues. The role requires extensive pharmaceutical regulatory affairs experience, leadership, project management, and expertise in submission and document management technologies.