Head of AI for IT
UK, USA & Spain
About the role
The Head of AI for IT leads the execution of AstraZeneca’s AI-for-IT strategy, developing, deploying and scaling AI across the IT function. The role embeds AI into core IT practices including the project lifecycle, IT operations, cloud migration, software development, quality, observability and service management. It builds and operates the foundational AI for IT platforms, and leverages enterprise platforms and standards for agent orchestration, knowledge systems and guardrails to deliver secure, reusable and scalable agentic AI. As AstraZeneca’s recognised internal expert for AI for IT, the role creates a global community that accelerates adoption, sharing and reuse while ensuring measurable value.
Key Responsibilities
The role is accountable for turning the AI-for-IT strategy into scaled, secure and measurable transformation across AstraZeneca IT globally
AI for IT Strategy and Development
- Develop and implement the AI-for-IT strategy to maximise speed and value across design, development, delivery, deployment, quality, compliance and operations.
- Use a value-stream approach to identify, prioritise and scale high-value use cases across IT.
- Define adoption roadmaps, investment priorities, operating measures and outcomes.
AI for IT Platforms
Influences IT platforms/tooling while leveraging EAI's token management, AI gateway, MCP gateway and agentic orchestration standards.
Leverage agent orchestration standards, knowledge systems, guardrails and Model Context Protocol platforms for agentic AI.
Contributes to the enterprise agent catalogue, owned by EAI, keeps agents consistently registered and linked to governance, cyber, legal and privacy.
AI-Native IT Practices
- Embed AI into the project lifecycle, software development lifecycle, testing, quality, compliance, cloud migration and operations.
- Partner on AI-native IT service management, including intelligent ticketing, resolution automation and proactive service management.
- Enable AI-assisted development, code review and testing through build-with and build-for principles.
- Advance AI-driven observability, anomaly detection, predictive incident management and AI Operations.
Token Economics and Operational Governance
- Partner with EAI on token economics on shared EAI tooling and standards
- Continuously optimise AI for IT value versus costs by adapting LLM models, their usage, architecture and operation.
- Ensure agents are secure, observable, resilient, compliant and cost-effective.
- Define measurable controls for lifecycle management, performance, risk and value realisation.
Community, Adoption and Expertise
- Act as a recognised internal expert for AI for IT.
- Create an IT community of practice that shares knowledge, assets, patterns and reusable agents.
- Influence leaders, product teams and practitioners to redesign work and adopt AI safely at scale.
Success Measures
- Collaborate with the Enterprise AI organisation to leverage existing AI platforms, standards, patterns and best practices.
- Encourage use of and contribute to enterprise standards for agentic AI development.
- Increased adoption and reuse of AI agents, platforms and shared patterns across IT.
- Faster delivery, higher engineering productivity and improved service performance.
- Measurable automation of IT workflows and reduction in manual effort.
- Improved reliability, observability, compliance and user experience.
- Transparent and optimised token consumption and AI operating cost.
Essential Skills, Capabilities & Experience
- Recognised thought leadership in applied AI, agentic AI or AI-enabled IT transformation
- Agentic AI architecture and orchestration
- Experience with agentic AI, Model Context Protocol, retrieval and enterprise knowledge systems
- Experience with AI-native ITSM, AIOps, developer tooling or cloud migration
- Knowledge of token economics, FinOps or consumption-based AI services
- Knowledge of LLMs and associated AI technologies, including their capabilities, applications, ecosystem, and regulatory landscape across the US, Europe, and China.
- Understanding of retrieval, knowledge graphs, semantic systems and model operations
- Platform product and engineering leadership
- Software engineering, IT operations and service-management fluency
- AI governance, security, compliance and observability
- Token economics and consumption optimisation
- Product mindset, value-stream thinking and outcome orientation
- Executive influence, storytelling and organisational change
- Community building, knowledge sharing and talent development
Why Join Us?
At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients, and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth, and development. We’re on an exciting journey to pioneer the future of healthcare.
If you are ready to take on this exciting challenge and be part of a team dedicated to revolutionizing talent acquisition in the pharmaceutical industry, we want to hear from you! Join us at AstraZeneca and let's make a real difference in the lives of patients around the world.
Office Working Requirements
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
Date Posted
09-Oct-2026Closing Date
23-Oct-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.Skills Required
- Recognized thought leadership in applied AI, agentic AI, or AI-enabled IT transformation
- Experience with agentic AI architecture and orchestration
- Experience with Model Context Protocol, retrieval, and enterprise knowledge systems
- Experience with AI-native ITSM, AIOps, developer tooling, or cloud migration
- Knowledge of token economics, FinOps, or consumption-based AI services
- Knowledge of LLMs, AI technologies, their ecosystems, applications, capabilities, and regulatory landscapes across the US, Europe, and China
- Understanding of retrieval, knowledge graphs, semantic systems, and model operations
- Platform product and engineering leadership experience
- Fluency in software engineering, IT operations, and service management
- Knowledge of AI governance, security, compliance, and observability
- Experience with token economics and consumption optimization
- Product mindset, value-stream thinking, and outcome orientation
- Executive influence, storytelling, and organizational change skills
- Community building, knowledge sharing, and talent development experience
AstraZeneca Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about AstraZeneca and has not been reviewed or approved by AstraZeneca.
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Fair & Transparent Compensation — Pay is considered competitive across many roles when total rewards are factored in. Senior scientific and leadership bands are described with high ranges that reinforce competitiveness at upper levels.
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Strong & Reliable Incentives — Bonuses, equity eligibility in many salaried roles, and solid sales on‑target earnings with upside are emphasized as meaningful parts of compensation. These elements boost overall value even where base pay is not the very highest.
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Retirement Support — A 401(k) program with a strong company match and immediate vesting is repeatedly cited as a standout. Generous retirement support is viewed as enhancing the total package relative to peers.
AstraZeneca Insights
What We Do
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