Top Remote Senior Level Jobs in St. Louis, MO

Senior individual-contributor backend engineer responsible for designing, building, and operating production-grade, highly available, strongly consistent services for wallet operations, transaction orchestration, blockchain integrations, and event-driven workflows. Implement secure, scalable APIs, cryptographic key management, Kafka-based event systems, observability with OpenTelemetry, CI/CD pipelines, and produce tests, API specs, and operational runbooks.

Own the technical side of deal progression for airline deployments: qualify opportunities, run demos and POCs, author integration and deployment architectures (PSS, APIs, data feeds, DNS, identity, networking), respond to RFPs/security questionnaires, scope SOWs and NFRs, and build reusable demo/reference assets to drive adoption and expansion while liaising between sales, engineering, and customers.

Founding product design role responsible for end-to-end UX for a B2B SaaS behavioral health platform. Design and iterate 0-1 features, prototype and produce pixel-perfect Figma assets, synthesize user research, translate PRDs into production designs, and support marketing/brand design needs.

Own and evolve high-scale backend and data-layer services. Design, build, test, and operate distributed backend services and APIs, improve reliability/latency/scale, take end-to-end ownership from design through production support, participate in on-call and incident response, and mentor peers while partnering with Product and SRE teams.

Translate, copy-edit, and post-edit English-to-Japanese content for marketing, product, UI, support, informational, and legal materials. Work remotely as an independent contractor, handling more than 5,000 words weekly with client-specific CAT tools. Candidates must deliver accurate, polished work on deadline, communicate reliably, respond to feedback, and collaborate on long-term localization projects.

Lead data science projects from ideation through enterprise impact, building scalable and well-tested solutions that improve healthcare outcomes. Apply probability, statistics, machine learning, SQL, and Python to develop data-driven products and insights. Partner with stakeholders, assess product performance, identify strategic improvements, mitigate risks, and mentor teammates while aligning initiatives with business objectives.

Lead technical direction for Elastic’s core billing platform across cloud providers. Design and operate scalable billing systems, data pipelines, APIs, and PostgreSQL architecture. Improve reliability, observability, incident response, deployment, and CI/CD practices. Partner with SRE, Cloud Infrastructure, Product, Design, and Finance teams, guide architecture and roadmap decisions, review technical work, mentor engineers, and participate in on-call rotations.

Lead end-to-end product design for Filevine’s legal work platform, including research, wireframing, prototyping, visual design, and specifications. Maintain the design system, create accessible user-centered experiences for complex workflows, collaborate with product and engineering teams, mentor junior designers, and use user feedback and product metrics to improve experiences.

Lead administrative and financial management of FINEP-funded strategic projects: ensure regulatory compliance, prepare transparent financial and budget reports, monitor expenditures, support R&D teams, and implement process improvements to optimize resource use and meet project milestones.

Lead architecture and implementation of scalable web applications using NestJS and Next.js. Build and optimize PostgreSQL schemas and queries, implement responsive UIs with Tailwind CSS, integrate LangChain-driven AI features, manage authentication with Clerk, and create end-to-end tests and automation with Puppeteer to ensure launch readiness and reliable user experiences.