Top Remote IT Jobs in San Antonio, TX

Provides Tier 1 help desk support for government information systems, including Tableau and Salesforce. Identifies, troubleshoots, documents, resolves, and escalates user issues; manages access changes and assists users with system access. The role logs tickets, collaborates with technical teams, supports projects, and develops work plans. Work may include weekends and holidays, with less than 10% travel and remote work options.

Lead global IT strategy and operations for a life‑sciences CRO: oversee cloud and infrastructure, cybersecurity and compliance (GxP/21 CFR/GDPR), enterprise applications and data strategy, digital transformation, vendor and budget management, and build a global IT organization to enable clinical research, data science, and product delivery.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

Manage endpoint devices, ensuring security and compliance via Microsoft Intune. Support escalated tickets, collaborate on projects, and handle vulnerabilities.

Lead human-centered design and front-end engineering for the NIH Data Lakehouse: conduct user research and testing; create wireframes, prototypes, flows, and accessible interfaces; build scalable React/Next.js/TypeScript UI components; integrate with GraphQL and search services; contribute to design systems, component libraries, and platform-wide front-end best practices.

Maintains provider demographic, credentialing, enrollment, participation, roster, and directory data across healthcare systems. Reconciles rosters, audits data quality, resolves discrepancies affecting claims and participation, supports credentialing and enrollment, produces operational reports, communicates with stakeholders, and recommends process and tooling improvements.

Designs, architects, deploys, and maintains multi-cloud solutions; secures and monitors systems; develops automation and scripts (Bash, PowerShell, Python); maintains documentation and SOPs; collaborates across teams, handles escalations, and advises implementation during infrastructure buildouts.

Lead the strategic direction of frontend engineering, architecture, tooling, and standards. Build accessible, high-performing React or Angular applications, component libraries, design systems, deployment pipelines, and testing strategies. Drive modernization, performance, accessibility, and developer-experience initiatives while collaborating with product and design teams. Mentor engineers, influence cross-team technical decisions, and contribute across the full stack when needed. The role is remote, requires U.S. citizenship and the ability to obtain Public Trust 6C, and involves up to 10% travel.

Oversee multiple enterprise IT programs and projects for the CIDO organization. Responsibilities include managing schedules, budgets, risks, dependencies, staffing, requirements, testing, training, deployment, and change management. The role coordinates business and IT teams, facilitates stakeholder workshops, prepares executive dashboards, supports acquisition and delivery of IT solutions, and aligns digital strategies across corporate, sector, and functional leadership.

Leads enterprise architecture for Biogen’s Veeva ecosystem across Development, Quality, Regulatory, Safety, and Commercial functions. Translates business needs into scalable Veeva configurations and integrations, governs target-state architecture and platform standards, reviews solution designs, and oversees implementation and release planning. Mentors configuration teams, drives cross-vault consistency, manages architecture governance, aligns with Veeva product roadmaps, and advises IT leadership on platform strategy, investments, regulatory compliance, and business objectives.

Leads DevOps and application operations for critical enterprise applications. Responsibilities include production reliability, SLO and SLA management, incident response, release and deployment operations, observability, automation, capacity planning, disaster recovery, security compliance, performance optimization, stakeholder service reviews, and mentoring AppOps engineers. The role supports 24x7 reliability through on-call participation and cross-functional collaboration with engineering, cloud, security, and compliance teams.

Leads the design, development, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system architecture blueprints, selects technologies, integrates distributed systems across on-premise and cloud environments, optimizes performance, ensures compliance with DoD requirements, and leads engineering teams. Diagnoses system issues, implements solutions, and produces architecture documentation while supporting installation, migration, and configuration activities across multiple client locations.

Leads the architecture, design, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system blueprints, selects technologies, integrates distributed systems across on-premises, cloud, and hybrid environments, optimizes performance, resolves system issues, and ensures compliance with DoD requirements. Leads engineering teams, supports installation and migration at multiple locations, and documents architecture and implementation decisions.

Owns and leads Regulatory IT systems supporting Global Regulatory Affairs and R&D. Responsibilities include maintaining technology roadmaps, managing system enhancements and implementations, overseeing vendors and releases, providing production support, delivering integrations, conducting data mapping and validation, and ensuring GxP, HIPAA, GDPR, and CCPA compliance. The role serves as the primary IT partner for regulatory business units, manages budgets, and coordinates cross-functional teams delivering regulated technology initiatives.

The Chief Information and Technology Officer leads Conduent’s global technology strategy, modernization, operations, engineering, data and AI initiatives, and security partnership. Responsibilities include developing enterprise technology roadmaps, overseeing cloud and infrastructure services, driving transformation and innovation, managing technology budgets and vendors, establishing governance, and improving resilience and service delivery. The CITO also builds global leadership talent, partners with executives and clients, and aligns technology investments with business growth and operational objectives.

Leads complex federal platform, cloud infrastructure, IT services, security, compliance, and disaster recovery initiatives. Coordinates AWS GovCloud infrastructure-as-code, deployment automation, observability, Zero Trust identity programs, FedRAMP High and DoD IL5 readiness, and operational resilience. Partners across Engineering, Security, Compliance, and Product to manage roadmaps, dependencies, risks, milestones, and audit readiness. The role also builds and mentors a Federal Platform Operations team and drives reliable, repeatable delivery practices.

The Senior IT Systems Administrator oversees the administration, security, and optimization of financial systems, ensuring reliability and compliance while leading system enhancements and integrations.

Designs and maintains automated testing frameworks, scripts, datasets, and tools for complex data-driven software. Develops test plans, performs exploratory, database, API, performance, and integration testing, and validates data accuracy across systems. Analyzes defects and test metrics, supports CI/CD pipeline integration, and collaborates with application teams to resolve issues. The role also uses Playwright, database scripting, cloud technologies, Agile practices, and generative AI tools to improve software quality and efficiency.

Design, develop, and operate Java-based cloud-native applications on Google Cloud Platform for image capture, processing, storage, and distribution. Build RESTful APIs, integrate AI capabilities, implement secure coding and authorization controls, and maintain CI/CD pipelines and infrastructure as code. Troubleshoot production issues, improve observability, participate in architecture and code reviews, and collaborate with DevOps, QA, product, and security teams.

Develop and maintain SailPoint IdentityIQ solutions supporting enterprise ICAM and IGA capabilities. Build workflows, rules, connectors, forms, provisioning integrations, application onboarding, lifecycle management, certifications, and entitlement governance. Integrate identity platforms with directories, HR systems, and enterprise applications; troubleshoot provisioning and aggregation issues; document technical solutions; and collaborate in Agile teams while supporting security, compliance, and mission readiness.

Designs and delivers secure, scalable AWS and Azure cloud solutions for application and data workloads. Translates customer requirements into architectures, develops Terraform infrastructure-as-code modules, and integrates CI/CD, automation, networking, identity, security, monitoring, and recovery capabilities. Owns solutions from discovery through implementation and operational transition while collaborating with Agile Cloud DevOps, security, infrastructure, and application teams. Supports specialized scientific and research platforms and provides trusted technical consulting to customers.

Deploys, hardens, troubleshoots, and modernizes Windows and .NET applications across on-premises environments and AWS. Responsibilities include Terraform infrastructure, CI/CD pipelines, SQL Server and Amazon RDS administration, load balancing, WAF configuration, observability, certificate management, automation, migrations, incident response, documentation, and collaboration with application owners. The role is remote but requires weekly onsite availability in Rockville, Maryland, and may involve occasional after-hours maintenance or outage troubleshooting.

Senior Cybersecurity Engineer to engineer and manage Tenable, Splunk, McAfee and other security tools; perform risk assessments, incident triage and coordination, system hardening, security posture assessments, develop security toolsets, and maintain awareness of threats and vulnerabilities in support of Department of State missions.

Designs and delivers secure, scalable cloud solutions across AWS and Azure for application, data, scientific, and research workloads. Partners with customers to translate requirements into architectures, develops Terraform infrastructure and automation, integrates DevOps and CI/CD capabilities, and manages solutions through implementation and transition to operations. Responsibilities include cloud networking, identity, security, monitoring, backup and recovery, troubleshooting, documentation, technical reviews, and collaboration within an Agile Cloud DevOps team.

Analyzes and improves business processes, gathers stakeholder requirements, develops user stories and acceptance criteria, documents workflows, and drives operational efficiency. Facilitates Scrum ceremonies, manages Jira tasks across Scrum and Kanban teams, supports backlog refinement, tracks sprint progress, removes impediments, and maintains traceability in Confluence. Partners with business, technical, data, and operational stakeholders to ensure requirements are implemented effectively and supports continuous improvement and data-driven decision-making.