Top Remote Senior Level Jobs in Indianapolis, IN

The Senior IT QA Engineer owns quality strategy and outcomes across complex technology initiatives. Responsibilities include designing automated testing solutions, integrating quality verification into CI/CD pipelines, analyzing quality and production data, developing dashboards, managing risk, leading root-cause analysis, and influencing product, engineering, architecture, security, operations, and business stakeholders. The role requires technical contributions across web, mobile, API, data, cloud, and distributed systems, plus mentoring engineers and advancing quality engineering practices.

Lead product, cloud, application, infrastructure, and internal security across Hipp’s healthcare SaaS platform. Responsibilities include architecture reviews, threat modeling, vulnerability management, cloud and identity security, monitoring, incident response, AI-agent security, compliance controls, vendor risk, customer security reviews, and security mentorship.

Own system-level testing for Lance and LanceDB across correctness, reliability, scalability, performance, data integrity, fault recovery, upgrades, and compatibility. Build automated test frameworks, realistic workloads, fault-injection scenarios, performance and soak tests, and reproducible CI environments. Investigate failures using logs, metrics, traces, and source code, create minimal reproductions, and partner with engineers on fixes. Apply AI tools responsibly to accelerate test development, failure analysis, and debugging.

Design and build production agentic AI systems and internal automation workflows across business functions. Responsibilities include prioritizing high-impact automation, developing multi-step and multi-agent workflows, integrating agent platforms, implementing human-in-the-loop controls, improving reliability and observability, evaluating performance, and shaping reusable AI engineering patterns. The role requires collaboration with nontechnical stakeholders and ownership of ambiguous problems from definition through measurable business impact.

Leads end-to-end business analysis for U.S. Department of Veterans Affairs systems, including requirements elicitation, documentation, user stories, process models, acceptance criteria, and traceability. Serves as the liaison between business stakeholders and technical teams, supports Agile ceremonies, manages Jira backlogs, performs impact analysis, supports testing and UAT, and mentors other analysts. Ensures solutions comply with VA security, accessibility, privacy, and delivery standards.

Senior software engineering individual contributor responsible for owning systems or feature areas, making customer- and business-focused technical decisions, improving an agentic AI development framework, managing automated quality and defect reduction, leading design discussions, mentoring engineers, and driving cross-pod technical initiatives. The role requires hands-on software engineering leadership without direct people management, with emphasis on AI-assisted development, testing, safety, and organizational technical strategy.

Secure AI/ML models, data pipelines, and AI-enabled applications by conducting vulnerability assessments, threat modeling, incident response, and security reviews. Build guardrails, monitoring, detection, access controls, encryption, and data-segmentation measures. Partner with engineering and analytics teams throughout the AI development lifecycle, assess third-party AI tools, document remediation plans, and translate emerging threats such as prompt injection, data poisoning, jailbreaks, and model-supply-chain risks into practical mitigations.

Develop and maintain PHP-based WordPress hosting platforms and products. Own features end to end, diagnose performance across application and infrastructure layers, write automated tests, modernize systems, improve deployment tooling, participate in code reviews, mentor engineers, and document decisions. The role requires deep WordPress and PHP expertise, Linux and hosting-stack knowledge, shell scripting, database and caching performance skills, and the ability to work autonomously on a globally distributed remote team.

Build ngrok’s foundational security engineering program, including security tooling, CI/CD guardrails, secrets scanning, vulnerability tracking, cloud security, risk assessments, AI security policies, detection capabilities, and incident response. Partner with engineering and leadership to establish security controls, automation, metrics, and reusable internal security platforms.

Own and improve security across cloud infrastructure, AI platforms, corporate IT, endpoints, identity, email, and business applications. Build detection and response capabilities, secure containers and software supply chains, implement identity and access controls, manage vulnerabilities and secrets, and automate security guardrails. Investigate threats across cloud, identity, and endpoint telemetry while protecting sensitive customer data and supporting compliance controls.