Top Remote Machine Learning Jobs in Charleston, SC

The AI/Machine Learning Specialist designs and implements AI solutions, collaborates with cross-functional teams, and continuously improves ML processes.

Design and lead end-to-end AI solution architectures, ensuring scalability, security, and compliance. Translate business and regulatory requirements into technical designs, evaluate tools/platforms, document architecture standards, coordinate technical teams, and support deployment and ongoing improvements.

Lead complex, cross-functional AI programs end-to-end: translate strategy into integrated plans, drive multi-team execution, mitigate risks (data, model, compliance), apply ML lifecycle practices, use Agile/kanban methods, manage budgets/vendors, communicate to senior stakeholders, and mentor other program managers to improve AI program standards.

Lead vision, strategy, and execution for Alkami's marketing products. Define roadmap, embed AI-driven personalization and audience intelligence, partner cross-functionally to drive adoption and revenue, recruit and develop product managers, and deliver scalable SaaS marketing and analytics solutions for financial institutions.

Design and implement machine learning models to solve business problems, analyze data for insights, and optimize model performance.

Lead technical pre-sales for large Oil, Gas & Energy accounts, define and implement Databricks-based data and ML/AI strategies, build technical champions, mentor teammates, and drive enterprise adoption through technical leadership and value selling.

Lead architecture and technical strategy for large Azure modernization and AI programs. Define reference architectures, drive cross-team execution, promote AI-augmented practices, mentor architects, guide discovery and delivery, ensure non-functional requirements (security, reliability, observability) are met, and create reusable assets to scale enterprise AI/ML adoption and platform modernization.

Designs enterprise AI/ML architectures, reference architectures, MLOps standards, lifecycle controls, and technical playbooks for the Veterans Health Administration. Provides consultation to AI pilot teams, evaluates vendor solutions, supports AI catalog and center-of-excellence planning, and translates federal security, authorization, interoperability, and risk requirements into executable architecture decisions. The role is remote and requires collaboration with program leaders, engineers, vendors, and VA IT teams.

Designs enterprise AI/ML architecture and product-management pipelines across the model lifecycle. Establishes MLOps standards, governance, risk management, monitoring, explainability, and compliance practices for responsible AI deployment at the VA. Advises governance bodies and senior leadership, evaluates tooling and platforms, supports CI/CD integration, and collaborates with engineering, data science, and product teams on scalable ML systems.

Lead statistical modeling, AI/ML evaluation, data governance, data quality assurance, and executive analytics for VA EHR modernization. Build reproducible R-based analytics, reporting pipelines, dashboards, and governed data products using R, SQL, Python, Git, and cloud platforms. Evaluate model reliability, bias, drift, and operational value; integrate complex healthcare data; define metrics and validation rules; and advise stakeholders on auditable analytical practices.

Manages client relationships and technology and analytics project delivery. Advises data science and engineering teams on business analysis, technology approaches, project scope, schedules, costs, risks, and quality assurance. Develops client engagement strategies, technology roadmaps, proposals, statements of work, and pricing. Partners with executives to identify portfolio growth opportunities and communicates the business value of analytics, statistics, and machine learning.

Designs and operates production multi-agent AI systems, LLM workflows, scoring and optimization algorithms, and closed-loop autonomous processes. Responsibilities include AI model evaluation, production monitoring, governance, third-party AI integration, federated data retrieval, and identifying patentable inventions. The role requires deep machine learning expertise, algorithm development, and deployment experience across complex operational environments.

Leads Mercury’s cross-line AI/ML research capability across insurance products. Responsibilities include setting strategy, building a research tooling team, modernizing workflows, developing model monitoring and AI infrastructure, establishing responsible AI guardrails, partnering across technology and data science teams, driving adoption, and coaching talent. The role requires strong quantitative, insurance analytics, Python, machine learning, generative AI, and LLM evaluation expertise, along with substantial people and cross-functional leadership experience.

Design and implement machine learning and optimization algorithms for Netflix’s ad marketplace. Build, train, and evaluate models using large-scale production data; develop online and offline evaluation frameworks; and partner with product teams to define objectives and trade-offs. Communicate technical decisions and experiment results to diverse stakeholders while providing technical guidance and aligning ML solutions with business goals.

Drive go-to-market execution across Nabla’s product portfolio, including positioning, messaging, sales enablement, competitive intelligence, demand-generation partnerships, customer adoption content, and event support. Progress into owning go-to-market strategy for specific products from early definition through launch and adoption, partnering with Product and Engineering and tracking launch success metrics.

Own credit portfolio performance analysis, credit policy, underwriting strategy, risk frameworks, and portfolio growth initiatives across lending products. Partner with Data Science, Product, Engineering, Operations, leadership, and external lending partners to develop predictive models, automated decisioning, analytical tools, dashboards, and reporting. Present strategic recommendations on portfolio risk, borrower behavior, credit expansion, and company-wide risk strategy.

The Sr. Machine Learning Engineer will develop and deploy ML solutions for healthcare, manage data pipelines, and work with large datasets to enhance healthcare delivery.

As a Staff Applied ML Scientist, you will develop and maintain fraud detection models, conduct research on fraud types, and collaborate across teams to drive product development and real-time decision-making.

As a Senior Applied ML Scientist, you'll develop fraud detection models, research new fraud types, and write production code while collaborating across teams to enhance SentiLink's identity verification solutions.

Lead end-to-end healthcare analytics projects, managing scope, planning, execution, client relationships, cross-functional collaboration, risks, and delivery. Provide thought leadership in healthcare analytics and identify business opportunities within client accounts. Required capabilities include quantitative analysis, project management, communication, presentation, SQL/Python/R proficiency, and strategic use of AI tools. Preferred experience includes consulting, cloud analytics platforms, healthcare data regulations, predictive modeling, machine learning, and data visualization.

Leads architecture and development of production-grade mapping and localization ML systems for autonomous vehicles. Designs neural models for detection, segmentation, tracking, depth estimation, 3D reconstruction, and semantic mapping; owns data strategy, evaluation, deployment, and fleet validation. Mentors engineers, drives technical roadmaps, collaborates cross-functionally, and advances vectorized HD mapping, foundation models, and real-time optimization.

Own end-to-end design for complex financial product experiences from exploration through launch and iteration. Translate financial workflows into intuitive customer experiences, set high standards for interaction and visual design, partner with product and engineering, use research and data to guide decisions, contribute to design systems, present work clearly, and mentor teammates. Apply AI-enabled tools thoughtfully while maintaining strong human-centered judgment.

Lead implementations of iQueue for Operating Rooms from discovery through configuration, validation, and rollout. Partner with hospital, clinical, operational, IT, and executive stakeholders to optimize OR workflows, scheduling, staffing, utilization, and access. Responsibilities include data analysis, solution design, product configuration, user acceptance testing, change management, risk monitoring, stakeholder alignment, and go-live readiness. Travel to customer sites is required up to 40–50%.

Lead initiatives in designing and building large-scale distributed data systems and ML infrastructure, while collaborating across various engineering teams.

Leads an engineering team building and scaling customer-facing integrations for agentic AI products. Responsibilities include setting technical direction, balancing customer delivery with reusable tooling and platform investments, ensuring reliability and observability, improving developer experience, collaborating cross-functionally, recruiting, and coaching engineers. The role requires customer empathy, strong engineering leadership, technical problem-solving, and experience with production systems or integrations.