Top Senior Python Jobs in Oklahoma City, OK

Reposted 8 Hours AgoSaved
Easy Apply
Remote or Hybrid
Oklahoma City, OK
Easy Apply
126K-248K Annually
Senior level
126K-248K Annually
Senior level
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills: Ai/Ml FrameworksMongoDBPypiPython
5 Days AgoSaved
Remote
Oklahoma City, OK
1M-2M Annually
Senior level
1M-2M Annually
Senior level
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills: AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
Reposted 9 Days AgoSaved
Remote
Oklahoma City, OK
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills: CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Reposted 11 Days AgoSaved
Remote
Oklahoma City, OK
Senior level
Senior level
Logistics • Software • Transportation
The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.
Top Skills: DockerFastapiKubernetesPostgresPulumiPythonTemporalVue
Reposted 11 Days AgoSaved
In-Office or Remote
Oklahoma City, OK
Senior level
Senior level
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills: CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
33 Minutes AgoSaved
Remote
Oklahoma City, OK
Senior level
Senior level
Information Technology • Logistics • Transportation • Consulting
Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.
Top Skills: .NetC#Ci/CdDevOpsDockerElectronFastapiGraphQLJavaJavaScriptLlmsLookmlMlMongoDBMySQLNode.jsPythonReact NativeReactRestSpringTypescriptVue
YesterdaySaved
Remote
Oklahoma City, OK
120K-145K Annually
Senior level
120K-145K Annually
Senior level
Software
Design, build, and maintain enterprise-quality Python serverless applications on AWS; integrate services and external APIs, implement state machines and CI/CD, write automated integration tests, troubleshoot and support production systems, and advise stakeholders on solutions.
Top Skills: AutomationAWSCi/CdCloudFormationEcs FargateEsbIntegration TestingPostgresPythonRest ApisServerlessSQLState MachinesWorkflow Engine
YesterdaySaved
Remote or Hybrid
Oklahoma City, OK
Senior level
Senior level
Artificial Intelligence • Information Technology • Software • Consulting
Build and maintain full-stack product features alongside cross-functional teams, contribute across architecture tiers, write tested maintainable code, collaborate with product managers, participate in re-architecture and technical design, and use logging and performance techniques to ensure low-latency, reliable user experiences.
Top Skills: AWSBigQueryDynamoDBGraphQLHTTPKafkaMySQLNeo4JNext.JsNode.jsOauthPostgresPythonRdsReactRestSnowflakeTypescriptVercel
Reposted 2 Days AgoSaved
Oklahoma City, OK
Senior level
Senior level
AdTech • Fintech • Information Technology • Database
Design and implement high-performance system software for medical devices, collaborating with hardware engineers and ensuring adherence to clinical standards.
Top Skills: C++Python
Reposted 2 Days AgoSaved
Remote
Oklahoma City, OK
Senior level
Senior level
Automotive
The Senior Software Engineer will build a large-scale data ingestion and classification system using web scraping, data processing, and search technologies, overseeing data extraction from various sources and developing search capabilities.
Top Skills: AirflowAWSElasticsearchKubernetesOcrOpensearchPythonScrapySpark
Reposted 3 Days AgoSaved
Remote
Oklahoma City, OK
Senior level
Senior level
Information Technology
The Senior Python Developer will design and implement secure backend systems using Python and Pyodide, ensuring compliance with DoD cybersecurity requirements and cloud deployment practices. Responsibilities include leading Python code optimization, supporting CI/CD pipelines, and participating in Agile sprint cycles, all while collaborating with cross-functional teams and ensuring secure coding standards.
Top Skills: 800-171APIsCi/CdCloud OneCmmcDevsecopsDisa StigsNist Sp 800-53PyodidePythonWebassemblyZero Trust
Reposted 4 Days AgoSaved
Remote
Oklahoma City, OK
Senior level
Senior level
Travel
As a Staff Software Engineer, you’ll lead the design and reliability of Duetto's data lakehouse, evolving data systems using Python and AWS, ensuring data quality, and implementing AI-driven solutions.
Top Skills: AirflowAWSDatadogDockerGithub ActionsGlueIcebergPysparkPythonSagemakerSentrySumo LogicTerraform
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Reposted 5 Days AgoSaved
Remote
Oklahoma City, OK
139K-203K Annually
Senior level
139K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.
Top Skills: AWSFastapiPython
Reposted 6 Days AgoSaved
Remote
Oklahoma City, OK
Senior level
Senior level
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills: Ai ToolsCi/CdGitGoKubernetesPythonReact
8 Days AgoSaved
Remote
Oklahoma City, OK
165K-215K Annually
Senior level
165K-215K Annually
Senior level
Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills: Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
9 Days AgoSaved
Remote
Oklahoma City, OK
130K-165K Annually
Senior level
130K-165K Annually
Senior level
HR Tech • Legal Tech • Software • Consulting
Design, implement, and maintain SaaS features using Python and React on AWS. Lead system design, code reviews, CI/CD pipelines, AI-integrated development (LLMs and AI coding agents), prompt engineering, testing (Cypress), and on-call production support. Mentor teammates and ensure secure, scalable, well-documented software.
Top Skills: AWSCicdClaude CodeCodexContainerized EnvironmentsCypressDevin.AiLlmMcpMySQLPython 3.11ReactRestful Apis
9 Days AgoSaved
In-Office or Remote
Oklahoma City, OK
160K-190K Annually
Senior level
160K-190K Annually
Senior level
eCommerce • Fintech • Payments • Software
Design and build end-to-end AI-driven automation to replace manual operational workflows. Partner with ops, sales, and support to discover problems, architect agentic orchestration, deploy production systems, measure impact, and iterate with robust guardrails and error handling.
Top Skills: Ai AgentsApexAutogenAWSAzureCi/CdClaude CodeCrewaiCursorGCPGitGithub ActionsGithub CopilotJavaScriptJIRALanggraphLightningLlmsPythonSalesforceSalesforce ApisSlackTypescriptWindsurf
Reposted 9 Days AgoSaved
In-Office or Remote
Oklahoma City, OK
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
13 Days AgoSaved
Remote
Oklahoma City, OK
Senior level
Senior level
Healthtech • Software
Lead backend development on the scheduling platform modernization, contribute across products, write APIs, and drive AI-accelerated software development workflows.
Top Skills: .NetAgent OrchestrationAi-Assisted DevelopmentLlm ToolingPython
13 Days AgoSaved
Remote
Oklahoma City, OK
Senior level
Senior level
Healthtech • Software
Lead backend development on the scheduling platform modernization. Contribute across Python and .NET ecosystems, write APIs, review code, and support AI-accelerated development workflows while collaborating in a remote team environment.
Top Skills: .NetAi-Assisted Development WorkflowsClaude CodeLlm ToolingMulti-Agent SystemsPython
4K-5K Hourly
Senior level
Travel
Lead development of Python-based web applications using Django and FastAPI, architect scalable solutions, and establish technical standards while mentoring developers and optimizing infrastructure.
Top Skills: Ai Coding AssistantsAWSDjangoFastapiGitPostgresPythonRailway
Reposted 16 Days AgoSaved
Remote
Oklahoma City, OK
180K-190K Annually
Senior level
180K-190K Annually
Senior level
Artificial Intelligence • Food • Software
The Senior Full Stack Engineer will develop scalable web applications using Python and React.js, mentor team members, and enhance system performance while leveraging AI technologies. The role emphasizes collaboration, end-to-end feature ownership, and architectural improvements in a remote setting.
Top Skills: AWSCi/CdClaude CodeCodexDatadogDockerGithub ActionsGraphQLMySQLNew RelicPostgresPythonReactRestful ApisSentrySQL
Reposted 19 Days AgoSaved
Remote
Oklahoma City, OK
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills: APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
Reposted 19 Days AgoSaved
In-Office or Remote
Oklahoma City, OK
Senior level
Senior level
Digital Media
Develop and enhance features for EnrollWise, contribute to a scalable software architecture, review code, collaborate on design and technical feasibility, and maintain software quality.
Top Skills: ApolloAWSDjangoDjango OrmGraphQLNextjsPythonReact
21 Days AgoSaved
Remote
Oklahoma City, OK
90-110 Annually
Senior level
90-110 Annually
Senior level
Digital Media • Professional Services • Consulting • Financial Services
The Senior Python Developer will enhance commerce and communication infrastructure by developing features, collaborating with stakeholders, ensuring system reliability, and integrating with third-party tools, while maintaining high-performance standards.
Top Skills: Ci/CdDockerFastapiPostgresPythonRabbitMQRedisStripe
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