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Top Senior Data Science Jobs in Des Moines, IA
Big Data • Marketing Tech
Design, build, and productionize complex Bayesian and probabilistic modeling pipelines. Lead methodology and technical direction, collaborate with Product/Data/Engineering, mentor data scientists, communicate results to stakeholders, and apply hierarchical, state-space, time-series, and graphical modeling at scale with strong emphasis on uncertainty and model validation.
Top Skills:
DynamaxGraphical ModelsHmcJaxMcmcNumpyroPymcPythonStanState-Space ModelsTime-Series ModelsVariational Inference
eCommerce • Software
Lead research defining fabric's AI shopping roadmap: design and run quantitative studies, build models and benchmarks for AI search (AEO/GEO), run experiments, translate findings into customer-facing insights, and publish research to influence product and go-to-market strategy.
Top Skills:
PythonSQL
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead end-to-end data science for customer-embedded, production solutions: acquire and prepare messy datasets, develop and evaluate models tied to business outcomes, run experiments, deploy operational models at scale, coach cross-disciplinary teams, and drive strategy, ethics, and privacy discussions.
Healthtech
Design, build, and deploy LLM-based applications and multi-step AI workflows (retrieval, orchestration, agents) using large-scale structured and unstructured data. Partner with engineering to productionize solutions, implement evaluation and safety measures, ensure compliance and data governance, and communicate results to technical and non-technical stakeholders.
Top Skills:
SparkAutogenAzureCrewaiDatabricksGCPLangchainLanggraphLlmPythonSnowflakeTransformer-Based Models
eCommerce • Internet of Things • On-Demand • Transportation
The Analytics Manager analyzes complex datasets, builds models, conducts scenario analyses, and provides strategic recommendations to guide decision-making for leadership.
Top Skills:
ExcelPythonSQL
Edtech
Lead advanced analytics and ML for partner-facing teams: build end-to-end predictive models (churn, lead scoring, health scores), marketing attribution and mix models, and maintain ML lifecycle standards. Develop agentic workflows and Claude Skills to accelerate work, mentor analytics team, and translate model outputs into actionable insights for Sales, Marketing, and CX.
Top Skills:
ClaudeClaude SkillsCursorLlm-Based AutomationsPrompt LibrariesPythonSQL
Big Data • Analytics • Business Intelligence • Big Data Analytics
The Senior Data Scientist will design and deploy time-series forecasting models, collaborate with stakeholders, and operationalize models in cloud environments, focusing on demand planning across various industries.
Top Skills:
AIArimaAzureData ScienceDemand ForecastingEtsGbmLightgbmMachine LearningPythonRandom ForestSarimaSQLTime-Series ModelingXgboost
Artificial Intelligence • Big Data • Database • Analytics • Consulting
Develop, validate, and deploy statistical and machine learning models on large structured and unstructured tax datasets to detect fraud, prioritize audits, and score compliance risk. Clean and explore data, perform feature engineering, collaborate with stakeholders, and present technical findings to diverse audiences.
Top Skills:
AWSBashCommand-Line ToolsCondaDatabricksDatabricks JobsGitGraph AnalyticsMarkdownNatural Language Processing (Nlp)PysparkPythonRSQLUnity CatalogVenv
Artificial Intelligence • Big Data • Database • Analytics • Consulting
Develop, validate, and deploy predictive and statistical models on large tax and financial datasets to detect fraud and non-compliance. Perform data exploration, feature engineering, and model evaluation using Python/R, SQL, and Databricks. Collaborate with government clients and cross-functional teams, deliver technical and non-technical briefings, and ensure models are explainable, defensible, and maintainable in secure government environments.
Top Skills:
AWSBashCommand-Line ToolsCondaDatabricksDatabricks JobsGitGraph AnalyticsMarkdownNlpPysparkPythonRSQLUnity CatalogVenv
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead end-to-end data science projects: acquire and prepare messy datasets, develop and evaluate models tied to business outcomes, operationalize models at scale, run experiments, drive ethics/privacy, partner with customers and teams, and coach cross-disciplinary colleagues.
Biotech
The Senior Associate Scientist will analyze and visualize data, collaborate on screening strategies, and validate hits for drug discovery using the EMMI platform.
Top Skills:
LinuxMoePythonRdkitSchrodingerSpotfireSQL
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead product and program analytics for Microsoft skilling experiences: design learner journey/funnel analyses, define success metrics, run experiments and causal analyses, build proficiency/competency models, shape telemetry and scalable reporting, recommend content and curriculum improvements, and mentor other data scientists to drive product decisions and learning outcomes.
Top Skills:
Azure Data Explorer (Adx)Azure Data Factory (Adf)DatabricksDelta LakeFabricKqlPysparkPythonRSnowflakeSQLSynapse
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Artificial Intelligence • Healthtech • Software • Biotech
Design and validate clinical and biomarker data pipelines, perform source-to-target mappings (e.g., EHR to data model), extend ontologies and vocabularies, ensure data quality, evaluate informatics tools, and support data architecture and analysis workflows for a regulatory-grade platform.
Top Skills:
Controlled VocabulariesEhrIcdLoincOntologiesPythonRSnomedSQLValue Sets
Healthtech • Social Impact
Build, deploy, monitor, and document predictive models and analytical reports; translate findings for non-technical stakeholders; ensure model quality, fairness, and explainability; collaborate with data engineers and train staff on data literacy; support production ML infrastructure on AWS.
Top Skills:
AWSAws SagemakerDeployment PipelinesModel RegistriesPandasPythonRRedshiftScikit-LearnSnowflakeTidyverseVersion Control
Security
The Geospatial Scientist leads data management initiatives, oversees data governance, and ensures quality and compliance of geospatial data for DHS.
Top Skills:
Arcgis EnterpriseEsri Geoportal ServerGeoplatform.GovGis Systems
Artificial Intelligence • Information Technology • Professional Services • Consulting
The Senior Data Scientist will design and deploy machine learning models, analyze complex datasets, develop analytical solutions, and mentor junior team members in a remote environment.
Top Skills:
Amazon AwsDatabricksGoogle GcpLookerAzurePower BIPythonPyTorchRScikit-LearnSnowflakeSparkSQLTableauTensorFlow
Logistics • Software
Lead development of digital twin and simulation models for warehouse operations, deploy AI-driven decision systems, build forecasting and optimization models, validate experiments linking operational metrics to financial impact, and partner with engineers, operations, and external AI/academic partners to scale innovations across fulfillment networks.
Top Skills:
Agentic AiAnylogicContinuous SimulationDigital TwinDiscrete-Event SimulationFlexsimLlmsMachine LearningOmsOptimizationPythonRSimioSQLWms
Marketing Tech • Mobile • Software
The Senior Data Scientist will analyze customer data, design experiments, build models, and support data-driven decision-making across product, marketing, and customer experience teams.
Top Skills:
BigQueryDbtPythonSnowflakeSQL
Fintech • Software • Financial Services
The Lead Data Scientist will enhance analytics through predictive modeling and data engineering, focusing on quality, feature generation, and continuous learning.
Top Skills:
DashGoogle Data StudioLookerPower BIPythonSQLStreamlitTableau
Digital Media • Fintech • Information Technology • Machine Learning • Financial Services • Cybersecurity • Automation
Develop, implement, and maintain ALM and CCAR/PPNR models for balance sheet forecasting. Build customer behavior, prepayment, and deposit models; monitor performance, perform backtesting and sensitivity analysis; collaborate with Model Risk, Market Risk, Treasury, and validation teams; prepare documentation and materials for governance and senior leadership; support balance sheet optimization and regulatory initiatives.
Top Skills:
AdcoBancwareBlack KnightBlackrockBloombergEconomy.ComEmpyreanFredNovantasPythonQrmR
Food
Lead retention and churn efforts by building survival and lifecycle-state models, classifying churn reasons, creating personalized win-back and next-best-action interventions, optimizing offers/promos, designing uplift experiments, and owning production model lifecycle, monitoring, and MLOps across Product, CRM, Marketing, and Engineering.
Top Skills:
A/B TestingChatgptCi/CdClaudeContainerizationDeep LearningEmbeddingsGradient BoostingMlopsModel RegistryOrchestrationPandasPythonRecommender SystemsScikit-LearnSQLSurvival ModelingUplift/Causal Inference (Econml)
Healthtech • Information Technology
The Senior Data Scientist leads data-driven initiatives, optimizing analytics for business decisions, mentoring staff, and ensuring data quality across healthcare projects.
Top Skills:
GCPMatlabPlsqlPythonPyTorchRSQLTensorFlow
Fintech
The Principal Data Scientist will design, develop, and deploy machine learning models, innovating methodologies and collaborating across teams to enhance financial decision-making and risk management.
Top Skills:
AirflowBentomlChalkDvcKubernetesMachine LearningMlflowNumpyPandasPydata StackScikit-LearnSpark
Fintech • Financial Services
Lead development of foundational marketing ML models (customer intent, next-best-action, marketing mix and attribution). Own model selection, explainability, monitoring, decisioning layers, and translate outputs into actionable recommendations for marketing and product stakeholders while providing technical leadership.
Top Skills:
DatabricksDbtLightgbmPythonPyTorchScikit-LearnSnowflakeSQLXgboost
Software
Lead development of Vanta's business analytics function: build scalable product data assets, define measurement frameworks, use AI-assisted analytics, partner with cross-functional teams, and deliver executive-level recommendations to drive product and business decisions.
Top Skills:
DbtLlmsMachine LearningPythonRSnowflakeSnowflake CortexSQL
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