Sr Biochemistry Scientist

Reposted 5 Days Ago
Be an Early Applicant
Madison, WI, USA
In-Office
91K-137K Annually
Senior level
Healthtech • Biotech
The Role
Develop, optimize, validate, and transfer biochemical and enzymatic assays in a cGMP laboratory to support manufacturing. Operate and train on lab equipment (HPLC, PCR, Tape Station, fragment analyzers, microplate readers), perform data analysis and reporting, author SOPs and transfer documentation, support cross-functional teams, troubleshoot technical issues, and contribute to continuous improvement.
Summary Generated by Built In
What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

You are the Senior Biochemistry Scientist Illumina is looking for in joining our Test Method Engineering team!  In your future role at the Madison site of the global front-runner in genetic sequencing, you will be one of a group of scientists who produce the fuel for Illumina’s sequencing, which is used in the study of genetic variation and function in realms from cancer research to agriculture.  

As part of a diverse, self-directed team, you will be responsible for driving method development and validation activities in a cGMP laboratory for analysis of a broad range of enzymes using-state-of-art processes and equipment.  You will also contribute to team driven improvement initiatives, engage in a curious and science-focused environment, and collaborate closely with cross-functional teams.   We want your talent, genuine curiosity about applied science, enthusiasm for creative problem-solving, and drive to get things done.

Job duties include, but are not limited to: 

  • Responsible for the development, optimization, characterization, and transfer of biochemical and enzymatic assays to support manufacturing operations.

  • Independently operate, maintain, and train others on key laboratory equipment platforms including fragment analyzers, microplate readers, HPLCs, PCRs, and Tape Station units.

  • Prepare method transfer documentation and lead method transfer activities to internal and external laboratories, ensuring reproducibility and compliance with quality standards.

  • Perform data processing, statistical evaluation, and interpretation of experimental results. Prepare technical reports, presentations, and documentation in accordance with internal GMP quality systems

  • Work closely with Quality Control, Manufacturing, Quality Assurance, Process Development, and global partner sites to support project execution.

  • Work independently and collaboratively as part of a scientific team and participate in team meetings and initiatives.

  • Edit and revise area work instructions and standard operating procedures (SOPs)

  • Contribute to investigation and resolution of technical issues.

  • Assist with continuous improvement and sustaining activities.

  • Perform analyses of processes, identify gaps and deficiencies, and proactively propose practical, data driven solutions.

  • Maintain organization and inventory of lab supplies, equipment, and reagents.

  • Ability to lift 40 lbs. in weight and stand for periods of time during the manufacturing processes.

  • Other duties that may be requested by management.

 Requirements:

  • 6+ years of industry relevant laboratory experience in biotechnology, biomedical, biochemical or pharmaceutical industry.

  • Advanced HPLC experience with proficiency in method development/optimization, assay validation and assay characterization.

  • Demonstrated ability to learn quickly and take initiative.

  • Demonstrated expertise in enzymatic assays and biochemical characterization techniques.

  • Excellent laboratory, organizational, and research skills.

  • Demonstrated ability to work on a diverse team.

  • Effective communicator with the ability to interface across functions.

  • Experienced in problem-solving and reasoning skills.

  • Proficient in Microsoft Word, PowerPoint & Excel. 

Education:

  • Typically requires a degree in biochemistry, chemistry, biology, or related field.  Bachelor’s degree with a minimum of 6+ years of relevant industry experience or Master’s degree with a minimum of 4+ years of relevant industry experience or PhD with 2+years of relevant industry experience preferred.

The estimated base salary range for the Sr Biochemistry Scientist role based in the United States of America is: $91,100 - $136,700. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [email protected]. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

Skills Required

  • 6+ years of industry laboratory experience in biotechnology, biomedical, biochemical, or pharmaceutical industry
  • Advanced HPLC experience including method development, optimization, validation, and characterization
  • Demonstrated expertise in enzymatic assays and biochemical characterization techniques
  • Experience operating, maintaining, and training others on fragment analyzers, microplate readers, HPLCs, PCRs, and Tape Station units
  • Experience working in a cGMP laboratory and following GMP quality systems
  • Ability to prepare method transfer documentation and lead method transfer activities
  • Experience with data processing, statistical evaluation, interpretation of experimental results, and technical reporting
  • Proficient in Microsoft Word, PowerPoint, and Excel
  • Effective communication, teamwork, problem-solving, and organizational laboratory skills
  • Ability to lift 40 lbs and stand for periods during manufacturing processes
  • Bachelor's degree in biochemistry, chemistry, biology, or related field (or equivalent experience) with specified industry experience
  • PhD with 2+ years of relevant industry experience (as stated preferred)

Illumina Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Illumina and has not been reviewed or approved by Illumina.

  • Healthcare Strength Health coverage includes comprehensive medical (HMO/PPO), dental, vision, mental health, life, and disability insurance with options such as FSAs/HSAs and wellness resources. Offerings are described as robust across regions with customization in certain locations.
  • Leave & Time Off Breadth Time-off programs include flexible schedules and remote work, PTO or flexible time off, paid holidays and sick leave, and volunteer time. Company-wide shutdowns during summer and winter add additional paid time away.
  • Parental & Family Support Family-focused programs include fertility assistance, adoption assistance, and reproductive health support alongside family medical leave. Paid parental leave is provided, with specifics varying by country and employment status.

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The Company
HQ: San Diego, CA
7,400 Employees
Year Founded: 1998

What We Do

Illumina is an innovative technology and revolutionary assays aiming the analyze genetic variation and function.

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