Jobs at Illumina

Own and sustain bonding equipment and processes for high-volume flow cell manufacturing. Troubleshoot mechanical, electrical, pneumatic, automation, instrumentation, and process issues; improve yield, throughput, utilization, reliability, and process capability. Develop experiments, DOEs, SPC responses, risk assessments, and equipment/software test plans. Maintain Camstar MES models, document validations and improvements, support new product transfers and equipment qualifications, and collaborate across Manufacturing, Quality, Engineering, and global sites.

Develop and implement production-grade bioinformatics algorithms for NGS secondary analysis, focusing on structural variant detection, pangenome references, graph algorithms, and assembly methods. Collaborate with software, FPGA, quality, testing, and clinical genomics teams while communicating technical findings to diverse audiences. The role requires strong genomics, algorithms, statistics, C++, and software development expertise.

Develop and improve bioinformatics algorithms for oncology applications, especially minimal residual disease detection in circulating tumor DNA. Responsibilities include prototyping NGS algorithms, analyzing variant and biomarker detection methods, designing experiments for oncology assays, collaborating with internal and external teams, providing technical guidance, and communicating results across functions.

Own and operate Illumina’s enterprise Databricks Lakehouse platform, including architecture, infrastructure automation, CI/CD, security, governance, reliability, disaster recovery, observability, FinOps, and AI/ML capabilities. Build reusable data engineering patterns, manage platform upgrades and roadmaps, establish engineering standards, and mentor engineers. Partner with global stakeholders and consuming teams to provide scalable, secure, self-service data platform capabilities.

Conduct applied research and development of sequencing reagents, consumables, methods, and chemistries. Design, optimize, analyze, and present experiments; troubleshoot technical challenges; investigate cross-functional problems; and develop innovative solutions with limited instruction. Maintain laboratory equipment and supplies while communicating findings through reports, presentations, and technical meetings.

Plans and manages facility construction, renovation, and space-planning projects across multiple locations. Responsibilities include feasibility studies, site master planning, budgeting, scheduling, resource planning, stakeholder coordination, construction documentation, contract and procurement support, bid review, compliance, and project closeout. The role partners with architects, engineers, contractors, consultants, leadership, and internal teams to deliver laboratory and office projects aligned with business needs and applicable standards.

Manages APAC tax compliance, including monthly tax calculations, financial data analysis, reconciliations, tax provisions, audits, statutory reporting, and responses to tax authority inquiries. The role researches tax regulations, collaborates with Finance and Tax teams, supports cross-functional projects, and improves tax reporting processes through optimization and automation.

Designs and develops complex electrical systems for genomic sequencing instruments. Responsibilities include board-level design, power and thermal management, simulation, board bring-up, troubleshooting, failure analysis, telemetry, EMI/EMC mitigation, performance monitoring, design verification, risk management, and cross-functional technical leadership for RUO and IVD products.

Leads mechanical design and development of DNA sequencing instruments, including precision electro-mechanical and fluidic mechanisms. Translates requirements into subsystem specifications, performs mechanical and thermal analyses, manages outsourced design and manufacturing partners, conducts risk analysis and verification testing, and supports product transfer into manufacturing. Requires strong expertise in robust electro-mechanical system design, tolerance analysis, GD&T, FEA, manufacturing processes, component selection, and SolidWorks. Travel to the US is required.

Leads mechanical design and development of precision electro-mechanical, fluidic, optical, and thermal subsystems for DNA sequencing instruments. Responsibilities include requirements definition, subsystem specifications, mechanical and thermal analysis, tolerance optimization, verification testing, risk analysis, outsourced manufacturing coordination, project scheduling, and product transfer to manufacturing. The role requires cross-functional collaboration, supplier management, and resolution of manufacturing and field issues.

Develops and transfers manufacturing processes for genomic consumables used in sequencing and array technologies. Responsibilities include molecular and particle characterization, plate-based assays, PCR and sequencing, DOE-driven process optimization, troubleshooting yield and quality issues, defining equipment requirements, authoring GMP procedures, training operators, analyzing results, and supporting production builds. The role collaborates with product development, supply chain, manufacturing, and quality teams to improve and scale robust processes.

Develops bioinformatics algorithms and analytical approaches for NIPT and clinical genomic products. Responsibilities include designing and analyzing experiments, conducting IVD validation and verification, applying statistical and computational methods, maintaining quality-compliant workflows, and collaborating with assay development, regulatory, and global bioinformatics teams.

Provides strategic leadership for Illumina’s multiomics bioinformatics portfolio, covering single-cell, spatial biology, proteomics, epigenomics, and emerging technologies. Leads bioinformatics scientists and engineers, defines informatics strategy and customer-facing workflow vision, drives AI-enabled innovation, and oversees programs from concept through commercial launch. Partners with product management, assay development, software engineering, clinical development, and commercial teams to align technology roadmaps with customer and business needs.

Leads clinical bioinformatics for end-to-end assay and application solutions, including novel algorithms on the DRAGEN platform. Oversees regulated genomic and multi-omic product development, manages globally distributed teams and managers, partners with customers and key opinion leaders, and guides innovation and competitive strategy across oncology, genetics, and reproductive health applications.

Conducts reagent formulation and stabilization research for NGS and microarray consumables. Designs and performs biochemical experiments, characterizes lyophilization and reagent stability processes, troubleshoots experimental issues, analyzes data statistically, documents results, writes technical reports, and collaborates across multidisciplinary R&D teams. The role also includes laboratory process and equipment ownership and communicating findings to leadership.

Develop enzyme production processes through protein purification, buffer preparation, formulation, functional and physical assays, process optimization, stress testing, inventory management, and experimental documentation. Analyze and present results, prepare reports, and troubleshoot results collaboratively. The role supports development of robust enzyme processes using chromatography, filtration, electrophoresis, spectroscopy, and fluorescence-based assays.

Design, develop, and maintain high-quality cloud-based applications within an Agile team. Collaborate on architecture, product requirements, and software development; troubleshoot production issues; evaluate technologies; provide technical leadership; and optimize performance through memory management, parallelization, and algorithm efficiency. The role also involves building multitenant database architectures, implementing secure APIs and event-driven systems, writing unit tests, and debugging complex software issues.

Develop and optimize bioinformatics algorithms and production software for Illumina’s DRAGEN platform and genomic analysis workflows. Analyze complex sequencing datasets, support germline, somatic, RNA, structural variant, CNV, and targeted sequencing applications, and collaborate with software, FPGA, quality, clinical genomics, and customer teams. Communicate scientific findings through documentation, publications, presentations, and marketing materials while evaluating new technologies to improve scalability, accuracy, and customer outcomes.

Administer and configure Workday HRIS systems, maintain global HR data integrity, troubleshoot integrations, develop reports and dashboards, and support HR process optimization. Consult with cross-functional stakeholders, train users, and manage HRIS-related projects through requirements, planning, risk management, testing, communications, and delivery.

Owns the full lifecycle of integrated marketing campaigns for SomaScan, including audience segmentation, paid media, marketing automation, launch, optimization, A/B testing, landing pages, analytics, dashboards, and stakeholder reporting. The role collaborates with Product Marketing, Sales, Creative, and Digital teams to drive brand alignment, conversions, revenue, and campaign ROI across digital and traditional channels.