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GRAIL is seeking a Senior Software Engineer for the Commercial engineering team within our Technology organization. Our team builds and operates the patient- and provider-facing software behind the Galleri® test, including my.grail.com and provider.grail.com, along with the systems that collect and deliver the clinical data the test depends on. The software we write sits directly in the path between a patient ordering a test and a physician acting on the result, so correctness, reliability, and clarity matter as much as velocity.
This is a backend-leaning full-stack role for an engineer who wants meaningful ownership. You will design and build cloud-native services in Go on AWS and Kubernetes, and you will follow your work through to the React interfaces that patients and clinicians actually use. You will own systems end to end — design, implementation, testing, rollout, and production operation — and you will help raise the bar for the engineers around you. If you want your work to have a direct line to earlier cancer detection, this is a rare place to do it.
This role is based in Sunnyvale, California. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site. At our Sunnyvale campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities.
Responsibilities
Design, build, and operate backend services and distributed systems that power GRAIL's commercial offerings for the Galleri® test, including my.grail.com and provider.grail.com.
Own features and services end to end, from technical design through implementation, testing, deployment, and production support.
Contribute across the stack, building and maintaining React interfaces used by patients, clinicians, and internal clinical operations teams.
Lead the technical design of projects of diverse scope, working independently and bringing designs forward for review at critical decision points.
Devise solutions where precedent is limited, adapting existing approaches and exercising judgment to select the right course of action.
Partner with product managers, clinical operations, and other engineering teams to turn ambiguous requirements into clear technical plans, advising senior stakeholders who may not share your technical background and adapting how you communicate to the audience.
Write and maintain automated tests and test protocols appropriate for software operating in a regulated healthcare environment.
Improve the reliability and observability of the systems you own, participating in on-call rotation, incident response, and follow-up remediation.
Raise engineering quality on the team through code review, pairing, and mentorship of less experienced engineers.
Identify and drive improvements to our tooling, CI/CD pipelines, and development practices.
These responsibilities summarize the role's primary responsibilities and are not an exhaustive list. They may change at the company's discretion.
Required Qualifications
Bachelor's degree in Computer Science, Electrical Engineering, Bioinformatics, or a similar technical field with 5+ years of related experience, or a Master's degree with 2+ years of related experience, or a PhD, or equivalent experience.
Professional experience designing, developing, testing, and maintaining production backend or full-stack applications.
Professional experience building and operating services on a major cloud platform such as AWS, GCP, or Azure.
Proficiency in at least one backend programming language such as Go, Java, Python, or C++.
Strong professional written and verbal communication skills.
Preferred Qualifications
Experience writing production Go, and experience with gRPC-based service communication.
Experience building and maintaining production React applications.
Hands-on experience with AWS specifically, including infrastructure as code using Terraform.
Experience operating containerized workloads with Kubernetes and Docker in production.
Experience designing and scaling microservice architectures, including service boundaries, versioning, and backward compatibility.
Strong working knowledge of relational databases such as PostgreSQL or MySQL, including schema design and query performance, and of caching layers such as Redis.
Experience with CI/CD pipelines, automated testing strategies, and agile development practices.
Experience building software in healthcare or another regulated domain, including familiarity with HIPAA, PHI handling, or software quality and validation requirements.
Experience with observability and reliability tooling, and a track record of improving system uptime.
Experience mentoring engineers or leading small project teams.
A demonstrated passion for designing and building practical, high-quality software, and a desire to add value to the team.
At GRAIL, we believe in recognizing and rewarding the contributions our employees make to our mission and success. In addition to base pay, this role may be eligible for additional compensation, including an annual bonus and/or other incentives, in accordance with applicable plans and the company's discretion. The posted range reflects our good-faith estimate of the base pay we expect to offer for this position at the time of hire. Actual compensation will be determined based on factors such as the candidate’s experience, skills, qualifications, and other relevant considerations.
At GRAIL, we invest in the health, well-being, and future of our employees and their families. Employees in this role are eligible for a comprehensive and competitive benefits package designed to support what matters most, including flexible time off or vacation, a 401(k) retirement plan with employer match, medical, dental, and vision coverage, and thoughtfully selected well-being programs. Benefits are offered in accordance with applicable plans and policies.
GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.
GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!
Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.
Skills Required
- Bachelor’s degree in Computer Science, Electrical Engineering, Bioinformatics, or a similar technical field with 5+ years of related experience; or a Master’s degree with 2+ years of related experience; or a PhD; or equivalent experience.
- Professional experience designing, developing, testing, and maintaining production backend or full-stack applications.
- Professional experience building and operating services on a major cloud platform such as AWS, GCP, or Azure.
- Proficiency in at least one backend programming language such as Go, Java, Python, or C++.
- Strong professional written and verbal communication skills.
- Experience writing production Go and using gRPC-based service communication.
- Experience building and maintaining production React applications.
- Hands-on AWS experience, including infrastructure as code using Terraform.
- Experience operating containerized workloads with Kubernetes and Docker in production.
- Experience designing and scaling microservice architectures, including service boundaries, versioning, and backward compatibility.
- Strong working knowledge of relational databases such as PostgreSQL or MySQL, including schema design and query performance, and caching layers such as Redis.
- Experience with CI/CD pipelines, automated testing strategies, and agile development practices.
- Experience building software in healthcare or another regulated domain, including familiarity with HIPAA, PHI handling, or software quality and validation requirements.
- Experience with observability and reliability tooling, with a track record of improving system uptime.
- Experience mentoring engineers or leading small project teams.
- Demonstrated passion for designing and building practical, high-quality software and adding value to the team.
What the Team is Saying
GRAIL Compensation & Benefits Highlights
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Healthcare Strength — Health coverage is described as comprehensive, spanning medical, dental, vision, disability, life insurance, and mental-health/wellbeing programs, plus backup care and family-forming support. Feedback suggests these offerings are a clear strong point of the package.
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Leave & Time Off Breadth — Flexible Time Off for exempt employees, paid holidays, and sick time are emphasized, and PTO is often described as flexible in practice. Feedback suggests this breadth supports work-life balance, even if usage can depend on team demands.
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Parental & Family Support — Paid parental leave is described as generous, and family-forming and backup-care resources are explicitly included. These supports are frequently highlighted as standout elements for caregivers.
GRAIL Insights
What We Do
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is using the power of high-intensity sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop and commercialize pioneering products.
Why Work With Us
Everything we do is guided by our mission to detect cancer early, when it can be cured. It’s the reason we’re here, and it’s no small task. The right people make all the difference. That’s why we’re looking for those who strive to share their knowledge, contribute their skills, inspire each other and commit to something bigger than themselves.
Gallery
GRAIL Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
GRAIL has a variety of work types depending on the roles. Some roles are onsite like a lab role, some are fully remote like our Galleri Sales Consultant roles. Others are hybrid with 3 days onsite.
