Principal Healthcare AI Systems Developer

Sorry, this job was removed at 08:13 p.m. (CST) on Monday, May 18, 2026
Easy Apply
Boston, MA, USA
In-Office
140K-228K Annually
Artificial Intelligence • Big Data • Healthtech • Machine Learning • Software • Database • Analytics
Powering the world’s most important systems with data that saves lives, runs businesses, and shapes the future.
The Role

The Data Platforms Health team builds native platform solutions that enable healthcare-specific platform capabilities. This development role in the Database Platforms department will contribute to AI-based features and workflows within the InterSystems Health Connect Cloud, InterSystems FHIR Server, InterSystems IRIS for Health and InterSystems Health Connect products.

The team needs a developer who can drive AI model and AI architecture design and development for intelligent tooling features for healthcare builders and administrators. The team also needs thought leadership to adopt evolving AI technologies so that InterSystems can be a leader in AI-driven features and workflows.

You are encouraged to apply if this role sounds interesting to you, even if you have doubts about being a competitive candidate. InterSystems prides itself on investing in its team members.

This position is in the InterSystems headquarters in Boston, MA.

Responsibilities

You will design, build, train, and deploy machine learning and agentic AI models, and consume LLMs and custom models using REST APIs. Working with product management and support specialists, you will design and implement data cleansing and feature extraction tools to improve the accuracy of predictions and data generation for a healthcare setting. Your responsibilities will include integrating the models into existing products and refining the models to meet evolving product needs.

All work must follow the team’s development workflow including use of source control, design and code reviews, and clear documentation. You are responsible for the quality of your code and must design automated tests to verify the effectiveness of the models and features.

This role will require you to respond to technical questions about expected product behavior and recommended best practices from support specialists and sales engineers. You will also collaborate with the release engineering team to ensure that your model and tools are appropriately deployed in cloud and on-prem environments.

The technology stack includes Python, AWS Bedrock, ObjectScript, and InterSystems IRIS.

As a leader, you are expected to create project plans with estimates, track execution against the plan, and proactively communicate anticipated delays in the project. With support from your manager, you will coordinate with other teams and overcome blockers and inter-team misalignments to deliver your projects. You will also provide thought leadership in the areas of Gen AI, agentic AI, and other evolving technologies, and encourage other team members to adopt these technologies for the platform.

Qualifications Required

  • Bachelor’s degree in Computer Science, Engineering, or a related technical discipline.
  • 8+ years of hands-on professional experience as a software developer or similar. Open to considering less experience in combination with a Graduate degree.
  • Experience with data analysis, data cleansing, feature extraction, and model training.
  • Experience with Python and common libraries like Pandas, NumPy, and Scikit-learn.
  • Experience with model training and evaluation.
  • Experience with Agent orchestration and runtime, MCP, tool registration, and multi-model routing.
  • Experience with design or consumption of REST APIs.
  • Strong verbal and written communication skills.

Preferred Qualifications

  • Self-starter with curiosity to experiment and learn, and confidence to challenge the status quo.
  • Professional experience with machine learning algorithms like neural networks and LLMs.
  • Professional experience with programmatic access of LLMs and/or open-source models.
  • Experience with observability of model performance and runtime costs.
  • Experience with model governance and design of guardrails for model security.
  • Professional experience with deep learning libraries like TensorFlow, PyTorch, or Keras.
  • Professional experience with health messaging standards, especially FHIR.
  • 3+ years of experience with other programming languages like Java, C#, C++, or ObjectScript.

We are an equal-opportunity employer and do not discriminate because of race, color, religion, sex, national origin, ancestry, marital status, veteran status, age, disability, sexual orientation or gender identity or expression or any other legally protected category. InterSystems is an E-Verify Employer in the United States.

InterSystems is providing a current good faith estimate of the anticipated base salary range for this position depending on a variety of factors including experience, education, skills, and performance.

Other compensation may include a discretionary annual variable target incentive.

The company also provides generous employee benefits including:

  • Medical, vision, and dental insurance
  • Short-term and long-term disability, and life insurance
  • 401(k) Profit Sharing Contribution
  • Paid Time Off and Holidays
  • Parental Leave
  • Tuition reimbursement
The estimated base compensation range for this role is:
$140,000$228,000 USD

About InterSystems

InterSystems, a creative data technology provider, delivers a unified foundation for next-generation applications for healthcare, finance, manufacturing, and supply chain customers in more than 80 countries. Our data platforms solve interoperability, speed, and scalability problems for large organizations around the globe to unlock the power of data and allow people to perceive data in imaginative ways. Established in 1978, InterSystems is committed to excellence through its 24×7 support for customers and partners around the world. Privately held and headquartered in Boston, Massachusetts, InterSystems has 38 offices in 28 countries worldwide. For more information, please visit InterSystems.com.

What the Team is Saying

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InterSystems Compensation & Benefits Highlights

  • Leave & Time Off Breadth A tiered PTO structure starts at a generous level and is complemented by separate paid holidays. Feedback suggests time off is a standout element from day one in the U.S.
  • Healthcare Strength Comprehensive medical, dental, and vision coverage is paired with EAP and wellness offerings, with some onsite or near‑site services in select locations. Feedback suggests these benefits are consistently viewed as strong.
  • Retirement Support A 401(k) with employer‑funded profit‑sharing is positioned as competitive with common match programs, alongside disability options and access to financial tools/advisors. Feedback suggests the overall design supports longer‑term financial planning.

InterSystems Insights

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The Company
HQ: Boston, MA
2,407 Employees
Year Founded: 1978

What We Do

InterSystems builds the software that makes complex systems work—reliably, securely, and at scale. For more than 45 years, we’ve been the information engine behind some of the world’s most mission-critical applications in healthcare, government, and business. Our data management, integration, and analytics technologies help organizations connect disparate systems, turn data into insight, and deliver better outcomes. From enabling interoperable healthcare and advancing clinical care, to powering national infrastructure and large-scale enterprise systems, our technology is used every day by millions of people in more than 80 countries. What sets InterSystems apart is not just what we build, but how we build it. We focus on long-term innovation, deep engineering excellence, and solving hard problems that truly matter. Our teams work closely with customers to tackle real-world challenges—often behind the scenes, but always at the heart of what keeps essential systems running. If you’re motivated by meaningful work, technical depth, and the opportunity to have a global impact, you’ll find it here.

Why Work With Us

Because we are a profitable, privately-held software company, we place our clients first in everything we do. You’ll work on meaningful, complex problems alongside deeply curious experts in a culture that values learning, ownership, and long-term growth—without the pressure of quarterly Wall Street demands.

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