Executive Director, AI Portfolio, Value Realization, Strategy & Operations

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We're looking for an Executive Director, Portfolio, Value Realization, Strategy & Ops to join our fast-moving Enterprise Data & AI organization. You'll act as the internal strategist and investment steward for our enterprise AI and data agenda, owning the roadmap, investment prioritization, and ROI tracking that ensures every AI dollar delivers measurable value. You'll serve as the key connector between the AI portfolio and executive stakeholders, telling a clear story of where we're investing, what it's returning, and what comes next. This role reports to the SVP, Chief AI Officer, and offers the chance to shape how a science-driven company invests in its AI future.

When & where:

• Location: Sleepy Hollow NY
• Work model/flexibility: 4 days a week on-site

Discover your role:

• Own the enterprise AI and data roadmap, turning business and scientific priorities into a sequenced, well-justified portfolio
• Lead planning and review processes for the Enterprise Data & AI organization, including annual planning and quarterly reviews
• Manage AI and data initiatives as a disciplined investment portfolio, with clear sponsors and outcomes for each
• Build and run a value realization framework that ties every AI initiative to a measurable business result
• Set enterprise strategy for generative AI tools, including buy, license, or build decisions and total cost modeling
• Lead the enterprise AI product management function, including roadmaps and adoption accountability
• Manage vendor relationships across the AI tools landscape, including negotiations and performance tracking
• Serve as the main point of contact for executive stakeholders on AI strategy, performance, and investment decisions

This role might be for you if you:

• Have a track record of connecting technology investment to measurable business results
• Enjoy building frameworks and processes from the ground up
• Bring strong strategic and financial thinking, including modeling trade-offs and building ROI frameworks
• Stay current on the AI landscape, including generative AI, agentic systems, and enterprise AI platforms
• Know how to build product management practices for AI capabilities
• Can influence and build trust across a matrixed organization without relying on formal authority
• Bring genuine curiosity about how AI is transforming drug discovery and clinical development
• Enjoy developing and growing strategy and product talent

This role requires:

• A Bachelor's degree in a related field (advanced degree required for certain scientific or clinical positions)
• 17+ years of experience in enterprise strategy, portfolio management, or AI/data leadership

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter. 

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)