Director, US Hospital Portfolio Strategy

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2 Locations
Remote or Hybrid
177K-283K Annually
Artificial Intelligence • Healthtech • Machine Learning • Natural Language Processing • Biotech • Pharmaceutical
We’re in relentless pursuit of breakthroughs that change patients’ lives.
The Role
The Director, US Hospital Portfolio Strategy will play a critical leadership role in shaping and executing market-based strategies that impact the $1.7B Pfizer US Hospital portfolio. This leader will guide cross‑functional US Business initiatives that drive revenue, margin improvement, and operational excellence across the entire US GH&B business.
This leader will lead cross‑functional teams and influence decision‑making across US Portfolio, Supply Chain, the broader US commercial organization and supporting functions. A key focus will be partnering closely with the US Hospital Portfolio Marketing team to design and deliver high‑value programs that support portfolio growth and Operating Plan achievement.
The role will have significant accountability for demand pull-through, excess & obsolete (E&O) inventory reduction, GH&B margin improvement targets, and portfolio growth revenue/margin metrics. They will also oversee the Hospital OPEX budget, ensuring disciplined investment aligned with business priorities.
Success in this role requires exceptional strategic thinking, communication, and collaboration skills, with the ability to influence senior leaders and drive alignment across Commercial, Supply, Legal, Regulatory, Contracting, National Accounts, and other key partners.
ROLE RESPONSIBILITIES
  • Lead cross‑functional portfolio, Sales, and Account Management efforts to develop, implement, and track quarterly revenue and margin‑generating programs that support Operating Plan performance
  • Drive pan‑portfolio margin improvement initiatives in partnership with Manufacturing, with a strong emphasis on identifying, mitigating, and reducing excess & obsolete (E&O) inventory risk
  • Manage and enhance key business reporting, including contributions to dashboards, portfolio performance tracking, and monthly business highlights
  • Lead strategic, US pan portfolio initiatives, including business development opportunity assessments, allocation playbook development, and cross‑functional manufacturing‑related projects
  • Partner with Sales, Account Management, and Customer Strategy to identify and implement strategies that maximize molecule value with organized customers across Hospital, Alternate Site, and IDN segments
  • Collaborate with Customer Strategy & Account Management to advance continuous improvement of supply program management processes, tools, and customer‑facing resources
  • OPEX management for the Hospital business, including budget tracking, marketing/market research funding, freight, and accrual processes, ensuring disciplined use of funds

BASIC QUALIFICATIONS
  • Bachelor's degree in business, science or related field
  • Minimum of 8 years in marketing, sales, contracting, finance, and/or relevant experience
  • Market Access experience, contracting with GPOs and IDNs, working with Trade (wholesalers and distributors)
  • Pricing analysis and determination, particularly with GPOs
  • P&L responsibility
  • Forecasting
  • Operating plan/latest estimate experience
  • US experience
  • Product/portfolio valuation, business case development, project management, product forecasting, cost of goods sold, pricing successes

PREFERRED QUALIFICATIONS
  • MBA or Master's degree preferred
  • Experience with pharmaceutical products in hospital, alternate site, and/or IDN or acute care center environment
  • Business case development experience

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Work Location Assignment: Hybrid
Other Job Details:
Last day to apply: February 24, 2026
The annual base salary for this position ranges from $176,600.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email [email protected] . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
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Pfizer Compensation & Benefits Highlights

  • Healthcare Strength Multiple U.S. medical plan options include telehealth, comprehensive mental‑health support, fertility/family‑building benefits, transgender‑inclusive coverage, and certain Pfizer medications at no cost. A Wellbeing Wallet and wellness resources broaden the health and wellbeing offering.
  • Retirement Support A 401(k) with company matching is paired with an additional Pfizer Retirement Savings Contribution, alongside company‑paid life and disability insurance. One‑on‑one financial planning support is provided through Fidelity.
  • Leave & Time Off Breadth Paid time off spans vacation, holidays, and personal days, with additional caregiver and medical leave. U.S. parental leave commonly includes 12 weeks paid with options for additional unpaid bonding time and a return‑to‑work transition.

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