The Role
Lead end-to-end hardware development for GutLab sampling systems: system architecture, CAD design, prototyping, validation, manufacturing scale-up, supplier alignment, field troubleshooting, and team leadership to ensure production-ready, reliable devices.
Summary Generated by Built In
Director of Engineering
Compensation: $150K– $200K salary, 0.25% - 0.5% equity stock options
Full benefits, including health coverage, PTO & parental leave
About BiomeSense
BiomeSense is a life sciences startup applying gut microbiome technologies (GutLab, MetaBiome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by LabCorp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners.
Role Summary
Own the full hardware (HW) lifecycle for GutLab, from architecture & subsystem integration through manufacturing, validation & deployment for a complex electromechanical device & BOM. Act as final technical authority for GutLab system performance, fleet stability & next generation GutLabs (Gen3) production, combining hands-on engineering depth with strategic judgment to ensure current systems perform reliably in the field & Gen3 scales into manufacturing.
Key Responsibilities:
Qualifications
Compensation: $150K– $200K salary, 0.25% - 0.5% equity stock options
Full benefits, including health coverage, PTO & parental leave
About BiomeSense
BiomeSense is a life sciences startup applying gut microbiome technologies (GutLab, MetaBiome) to advance personalized medicine. We partner with UCSF, UCSD, NIH & the University of Chicago & are backed by LabCorp Ventures, Bluestein Ventures, Seerave Foundation & Emil Capital Partners.
Role Summary
Own the full hardware (HW) lifecycle for GutLab, from architecture & subsystem integration through manufacturing, validation & deployment for a complex electromechanical device & BOM. Act as final technical authority for GutLab system performance, fleet stability & next generation GutLabs (Gen3) production, combining hands-on engineering depth with strategic judgment to ensure current systems perform reliably in the field & Gen3 scales into manufacturing.
Key Responsibilities:
- System Ownership & Development: Own GutLab architecture (electromechanical & fluidic); lead design, testing & refinement via CAD, prototyping & manufacturing
- Validation & Deployment Readiness: Own validation, stage gates, documentation & traceability across revisions, firmware & field performance. Lead troubleshooting, diagnostics & closed-loop fixes to eliminate systemic failure modes
- End-to-End Execution: Set & execute high standards for all aspects of HW development: procurement, transfer, sustaining engineering & operations
- Manufacturing Scale-Up: Drive DFM, design freeze, pilot builds, supplier alignment, cost targets & manufacturing strategy + execution for Gen3
- Team Leadership: Mentor & lead a HW team; align resources, timelines & execution to production milestones
- Strategic Problem Solving: Address any and all procurement challenges while identifying cost-effective solutions
- Cross-Functional Collaboration: Partner with other leaders to align hardware development with broader company strategy & goals
Qualifications
- 8+ years’ experience in hardware engineering for complex electromechanical systems
- Deep proficiency in CAD, tolerances, prototyping & manufacturing
- Product lifecycle ownership (concept through transfer & scale-up)
- Proven ability to build & manage technical teams
- Systems-level troubleshooting expertise across mechanical, fluidic & electronic
- Structured, decisive & execution-oriented with high accountability
- A strategic thinker who thrives under pressure in fast-paced environments
Skills Required
- 8+ years experience in hardware development and/or manufacturing for complex electromechanical systems
- Deep proficiency with complex CAD assemblies, tolerance analysis, prototyping, testing methodologies, and manufacturing processes
- Demonstrated ownership of full product lifecycle from concept to production
- Experience leading manufacturing transfer and production scale-up
- Proven ability to build and manage technical teams
- Strong systems-level troubleshooting capability across mechanical, fluidic, and electronic domains
- Structured, decisive, and execution-oriented with high accountability
- Strategic thinker who thrives under pressure in fast-paced environments
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The Company
What We Do
BiomeSense is a biotechnology company developing an integrated biosensor and AI-powered platform to massively scale the collection and analysis of gut microbiome data. By leveraging big data and artificial intelligence, the company provides continuous, longitudinal insights into the human microbiome to unlock the full potential of precision medicine and personalized healthcare solutions.
