Director, Advanced Analytics Lead, Strategic Insights & Analytics

How will your role help us transform hope into reality?

The Director, Advanced Analytics Lead will report to the US Head of Strategic Insights & Analytics (SI&A) and be a core member of team.  This person will be responsible for leading quantitative analyses of various datasets (including claims data, diagnostic lab data, internal promotional data).  They will lead efforts around the application of data analyses for executable Sales and Marketing tactics including HCP targeting, patient segmentation, referral networks, marketing mix modelling, as well as ROI measurement of tactics. The individual will leverage different analytical approaches to generate actionable insights to drive the continued commercialization success of AYVAKIT (avapritinib). They will work closely with multiple cross-functional partners including Commercial Operations, Marketing, Field Personnel, Market Access, and Commercial Leadership.

What will you do?

• Drive business performance through actionable insights derived from healthcare claims data by uncovering trends, opportunities, and barriers in rare disease (systemic mastocytosis) diagnosis, treatment, and patient journeys
• Design, execute, and interpret analyses of large healthcare datasets (including claims data, diagnostic lab data, multi-client supplier data, internal promotional data)
• Collaborate on strategic execution of actionable insights as well as track and measure outcome
• Identify novel AI use cases and lead successful execution and measurement of business impact
• Translate complex data findings into clear, actionable recommendations for commercial and cross-functional teams to drive revenue growth
• Provide strategic decision support by partnering with commercial operations, marketing, market access, and field teams to inform brand strategy, patient segmentation, HCP targeting, and resource allocation/optimization (by measuring impact of tactics)
• Support real-world evidence initiatives, including the design and execution of studies leveraging claims data to demonstrate disease burden, unmet need, and impact of AYVAKIT
• Collaborate with Commercial Operations and IT teams to ensure robust data infrastructure, quality, and compliance with privacy regulations
• Integrate claims data insights with other data sources (e.g., specialty pharmacy, digital engagement, EMR) to enable holistic, omnichannel commercial strategies
• Stay abreast of industry best practices, emerging analytics methodologies (AI applications), and regulatory requirements
• Combine technical expertise in advanced analytics with a deep understanding of the biopharmaceutical industry, especially in rare diseases
• Play a critical role in shaping commercial strategy, optimizing patient prediction, and supporting evidence generation for AYVAKIT
• Perform other responsibilities as assigned.

What minimum qualifications do we require?

• BA/BS degree required
• 8-10+ years of experience, including 4 years of direct involvement in advanced analytics using various datasets; 6-8+ years of experience if candidate has a PhD or MD degree

What additional qualifications will make you a stronger candidate?

• Advanced degree (MBA, MPH, PhD) or other equivalent experience a plus
• Demonstrated experience in rare disease analytics, with a strong understanding of the unique challenges in small patient populations, diagnostic journeys, and treatment landscapes
• Demonstrated track record showing high business impact by leveraging AI/machine learning
• Strong analytical skills, problem-solving, and critical thinking
• Proficiency in programming languages (e.g., SQL, Python, R) a plus
• Demonstrated experience working with cross-functional teams including Commercial Operations, Marketing, and Sales to deliver strategic tactics driving business performance
• Proven ability to influence brand strategy and tactical execution through data-driven insights and recommended actions
• Strong communication skills with executive presence
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, patients are our purpose. Their needs ignite our innovation, fuel our urgency and inspire us to go further - faster. We bet on bold people who want to grow, push boundaries and lead meaningful change. Here, you’ll do the most impactful work of your career - because our commitment to changing lives isn’t just what we do, it’s who we are.

Patients are waiting. Are you ready to make the leap?

Compensation and Benefits 

The base salary hiring range for this position will be $210,000 -- $275,000.* Actual base salary offered for this position will be based on a number of job-related factors, including, but not limited to: experience (including skills and competencies), education, training and internal equity.

This position is also eligible for the following:

• Participation in annual bonus program based on Company and individual performance, subject to the standard terms and conditions of the program
• Inclusive total rewards offerings focused on employee choice and professional and personal well-being. These include: medical, dental and vision benefits; Modern Health mental health and coaching benefits; medical and dependent care FSAs; generous paid time off (typically includes one-week well-being shutdowns at mid-year and year-end); subsidized commuting or parking benefits; 401(k) with match;  generous paid medical, parental and family leave programs; disability benefits and more.

*Based on reasonable estimate for this job at the time of posting; ranges are reviewed periodically and subject to change.

To apply, just scroll down and click on the “Apply Now” link. 

Equal Employment Opportunity

At Blueprint Medicines, we foster an environment of fair treatment and full participation for all of our employees as we navigate complex challenges in pursuing our mission to improve the lives of patients. We celebrate our unique differences and varied career and life experiences so that we can sustain our diverse culture and ensure everyone feels accepted. We are committed to non-discrimination, equal employment opportunity, as well as an inclusive recruitment process. We consider all qualified applicants based on merit and without regard to race, color, sex, gender identity, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable federal or state law.  

We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to [email protected]. We are also an E-Verify Employer. For more information, please see our EEO Policy Statement, the E-Verify Participation Poster, the Right to Work Poster, and/or the EEO Know Your Rights Poster.

Blueprint Medicines, a Sanofi company, is a global biopharmaceutical company that invents life-changing medicines. We seek to improve and extend patients' lives by solving important medical problems, with a focus on allergy/inflammation and oncology/hematology. Our approach begins by targeting the root causes of disease, using deep scientific knowledge in our core focus areas and drug discovery expertise across multiple therapeutic modalities. We have a track record of success with two approved medicines, including AYVAKIT/AYVAKYT (avapritinib) which we are bringing to patients with SM in the U.S. and Europe. Leveraging our established research, development, and commercial capability and infrastructure, we aim to significantly scale our impact by advancing a broad pipeline of programs ranging from early science to advanced clinical trials in mast cell diseases and solid tumors. For more information, visit www.BlueprintMedicines.com and follow us on X (formerly Twitter; @BlueprintMeds) and LinkedIn.