Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
About the Role:The Real World Evidence (RWE) group within the Pharma R&D team at Tempus works with major pharmaceutical partners to provide best-in-class data, analysis, and methodological guidance for Tempus’s real-world data offering.
We are seeking a highly motivated and solutions-oriented RWE Data Scientist II with experience and interest in oncology and epidemiological study design to join our team. This role requires the ability to lead observational studies, derive insights from complex real-world clinical data, implement advanced statistical methods, and leverage cutting-edge AI tools to scale tasks and augment insights.
Key ResponsibilitiesPharma Collaboration & Strategy: Partner with pharmaceutical collaborators to independently execute robust RWE research plans that leverage the Tempus multimodal platform to address key questions in trial design and outcomes research.
Real World Data Expertise: Lead the derivation of complex real-world endpoints using extensive coding, demonstrating deep comprehension of Tempus clinical and molecular data structures and complexity, while also serving as an expert on the methodological nuances and limitations of real-world data.
Methodology & Platform Contribution: Stay up-to-date on methodological advancements in real-world studies (e.g., causal inference, survival analysis) and oncology guidelines (NCCN and ongoing clinical trials) to contribute to reusable code, internal packages, and best practices that can be applied across multiple collaborations.
AI & LLM Innovation: Incorporate LLMs, agentic workflows and other AI tools into day-to-day workflows to accelerate code development, discovery, documentation, review, and insight generation.
Scientific Interpretation & Communication: Interpret results of RWE analyses to draw appropriate inferences based on study design/statistical methods, while also evaluating study limitations. Communicate complex methods and results clearly to both technical and non-technical stakeholders. Prepare and present internal reports, external-facing deliverables, and, where appropriate, manuscripts or conference materials.
Cross-Functional Collaboration: Collaborate with internal product, oncology, and clinical abstraction, and real-world data science teams to continually enhance Tempus data quality, products, and analytical best practices.
Education: Education in epidemiology, biostatistics, data science, public health, or a related field, to the level of either:
PhD
Master’s degree and 2+ years of additional work experience
Technical and Statistical Proficiency:
Proficiency with observational real-world healthcare data, including analytical experience with time-to-event methodologies (survival analysis).
Proven expertise in executing RWD analytical studies.
Proficient in using R and SQL, especially statistical tools and packages.
Proficiency applying machine learning, LLM-based coding assistants (e.g., Copilot, Cursor) and agentic frameworks to support data analysis, code review, or scientific documentation workflows.
Adherence to good software engineering practices (version control, modular code, documentation).
Communication & Client Focus: Demonstrated experience interfacing with clients, showcasing adeptness in presenting and tailoring messaging to a variety of stakeholders.
Soft Skills: Excellent written and verbal communication skills with strong project management skills. Ability to thrive in a fast-paced, dynamic environment working with multi-disciplinary scientists on complex problems.
- Experience working with Pharma or drug development.
Experience in clinical trial design (particularly Phase II-III) in the clinical development space.
Analytical proficiency with claims, EHR, or registry data.
Practical experience configuring or adapting LLMs, or using related tools/frameworks, to support scientific work.
Knowledge of oncology guidelines (e.g., NCCN).
Experience with biomarker or molecular data (e.g., genomics).
Experience with cloud platforms such as AWS and/or BigQuery and/or Google Cloud Platform (GCP).
CHI: $90,000-$135,000 USD
NYC/SF: $100,000-$150,000 USD
The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
What the Team is Saying
What We Do
We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time, connect patients with therapies and clinical trials, and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data, Tempus partners with more than half of U.S. oncologists and the majority of the top 20 global pharma companies. Our teams are pioneering work across oncology, neurology, psychiatry, cardiology, and beyond—transforming how care is delivered and therapies are developed. At Tempus, every role contributes to our mission: to help each patient benefit from the experiences of those who came before. For more information, visit tempus.com.
Why Work With Us
We’re looking for people who can change the world. People who question the status quo and refuse to shy away from tough problems. For builders who are never done building, and the learners who are never done learning. Passionate individuals with undying curiosity who want to take on one of the greatest challenges humanity has ever faced—head on.
Gallery
Tempus AI Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
Most of the team follows a hybrid policy, with some roles allowing for a fully remote arrangement and some roles being onsite only.
