Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases.
We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients.
At argenx, we’re all in on our innovation mission to transform care for people living with severe autoimmune diseases. We speak the language of science, put patients first, and value high‑impact over hierarchy. If you’re energized by bold ideas and collaborative problem‑solving—patients are waiting.
The opportunity
At argenx, biomarkers are a key driver of how we design trials, make decisions, and bring precision therapies to patients. As a Biomarker Biostatistics Lead, you will shape and drive the strategic use of biomarkers across the drug development lifecycle—from early translational research through late-phase clinical development and beyond. You will partner cross-functionally to ensure that biomarker data is analysed and actively informs program decisions, de-risks development, and strengthens our clinical and regulatory strategies.
What you’ll do
Partner in shaping biomarker strategies from a quantitative perspective, ensuring that biomarker proposals are supported by robust, fit for purpose statistical approaches aligned with key program questions and decision points across development.
Translate scientific and clinical questions into decision relevant quantitative approaches, driving the identification, execution, interpretation, and optimization of biomarker analyses to support the assessment of diagnostic, prognostic, pharmacodynamic, and predictive value of biomarkers in a clinical and translational context.
Act as a strategic partner to Clinical, Biomarker, and Translational teams, influencing study design, biomarker selection, and evidence generation approaches early and throughout development.
Drive the integration of biomarker and clinical data, enabling cross-study learning, reverse translation, and program-level insights.
Ensure that biomarker analyses are fit-for-purpose, balancing scientific exploration with clinical and regulatory relevance (i.e. “measure what matters”).
Guide the evolution from exploratory insight to actionable evidence, supporting biomarker qualification and readiness for clinical and regulatory use where applicable.
Promote reproducibility and robustness, ensuring analyses are transparent, traceable, and aligned with ALCOA++ and regulatory expectations.
Influence and mentor across functions, elevating statistical thinking and shaping consistent, high-impact biomarker practices across the portfolio.
Represent biomarker biostatistics in strategic and governance forums, contributing to key development and investment decisions.
What you’ll bring
Advanced degree in Biostatistics, Statistics, or related field; significant experience in pharma/biotech clinical development
Relevant working experience and strong expertise in statistical methodologies for clinical and biomarker data (e.g. longitudinal models, surrogate markers, survival analysis, multiplicity)
Demonstrated experience working with biomarkers in a decision-making context (e.g. predictive, PD, prognostic, stratification).
Proven ability to translate data into clear scientific and clinical recommendations for stakeholders and senior decision-makers.
Experience contributing to biomarker strategy and/or regulatory discussions is a strong plus.
Proficiency in R and reproducible analysis workflows; experience with complex/high-dimensional datasets.
Strong collaboration and influencing skills in cross-functional environments.
Why argenx
We dare to do more—together. At argenx you’ll join a global immunology biotech where the science of co‑creation drives bold goals and real patient impact. You’ll find high‑impact over hierarchy, and a culture where Argonauts collaborate across borders to turn precision science into medicines.
Offer
Member of a cross-disciplinary team involved in clinical development of therapeutic antibodies.
Opportunity to contribute to the continued build-out of the Translational Data Science team.
Competitive salary package with extensive benefits.
This job is eligible to participate in our short-term and long-term incentives program.
The hiring range displayed above is the range of possible base pay compensation that argenx believes in good faith it will pay for this role at the time of this posting. The hiring range is based on the job grade for this position. Individual compensation paid within this range depends on a variety of factors, including, but not limited to, internal equity, prior education and experience, job-related knowledge and demonstrated skills. argenx may pay more or less than the posted range and this range may be modified in the future.
At argenx, all applicants are welcomed in an inclusive environment. They will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics. argenx is proud to be an equal opportunity employer.
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Skills Required
- Advanced degree in Biostatistics, Statistics, or related field
- Significant experience in pharma/biotech clinical development
- Expertise in statistical methodologies for clinical and biomarker data (e.g., longitudinal models, surrogate markers, survival analysis, multiplicity)
- Demonstrated experience working with biomarkers in a decision-making context (predictive, PD, prognostic, stratification)
- Proficiency in R and reproducible analysis workflows
- Experience with complex/high-dimensional datasets
- Proven ability to translate data into clear scientific and clinical recommendations for senior stakeholders
- Experience contributing to biomarker strategy and/or regulatory discussions
- Strong collaboration and influencing skills in cross-functional environments
What We Do
argenx is a global immunology company committed to improving the lives of people living with severe autoimmune diseases. Partnering with leading academic researchers through its Immunology Innovation Program (IIP), argenx is translating immunology breakthroughs into a world-class portfolio of novel antibody-based medicines.
