Jobs at Structure Therapeutics

Leads DMPK strategy and execution for preclinical small-molecule drug programs. Oversees ADME and PK studies, CRO collaborations, PK/PD modeling, toxicokinetic analysis, DDI risk assessments, regulatory contributions, and clinical dose optimization. Integrates DMPK data across cross-functional development teams and supports regulatory submissions and health-authority interactions.

The Principal Data Scientist will lead the development of AI-powered data science tools, collaborating with cross-functional teams to enhance clinical research and optimize trials. Responsibilities include designing scalable solutions, ensuring software reliability, and communicating insights effectively.

The Data Scientist will enhance the platforms, develop tools for clinical research, and ensure reliability of analytical solutions using software engineering best practices.

The Senior Patent Agent will oversee the intellectual property portfolio, draft new applications, guide IP strategies, and support patent prosecution efforts.

The role focuses on computational chemistry, employing molecular dynamics and cheminformatics for small-molecule drug discovery and optimization. Collaborates with multidisciplinary teams to influence therapeutic design.

The Sr. Director of Commercial Supply Chain leads supply chain operations, ensuring steady drug supply, demand forecasting, and cross-functional collaboration for clinical and commercial programs.

The Associate Scientist/Scientist in DMPK will develop bioanalytical methods and analyze samples for small molecule projects, collaborating with cross-functional teams.

Lead end-to-end semi-monthly payroll for US employees via ADP TotalSource, coordinate EMEA payroll, process off-cycle and equity taxable events, ensure payroll tax compliance and SOX controls, prepare payroll journal entries and reconciliations, review Ramp expense coding, support month-end close and external audit PBC documentation.

Senior technology leader for China operations responsible for IT strategy, infrastructure, service delivery, cybersecurity, vendor and budget management. Partners with China and Global leadership to deploy enterprise systems, support research and clinical functions, and ensure compliance with global standards and local regulations while building a high-performing regional IT team.

Lead development and governance of Structures Knowledge System: ontologies, semantic enrichments, data catalog, curated datasets, and digital twins. Build and manage data engineering pipelines for AI, enforce FAIR principles, oversee data stewardship and GxP-compliant governance, enable vendor evaluations, and align data roadmaps with Clinical, CMC, R&D, Commercial, and G&A stakeholders.

Lead in vivo pharmacology studies, troubleshoot experimental challenges, ensure data integrity, and mentor junior scientists while supporting drug discovery projects.

Support participant recruitment and retention for clinical trials by designing and executing recruitment/retention plans, collaborating with sites/CROs/vendors, engaging advocacy groups, conducting market research on patient barriers, creating site and participant materials, and analyzing trial metrics to optimize enrollment and retention. Travel to sites and meetings (40-50% US-based).