Jobs at Structure Therapeutics

Support participant recruitment and retention for clinical trials by designing and executing recruitment/retention plans, collaborating with sites/CROs/vendors, engaging advocacy groups, conducting market research on patient barriers, creating site and participant materials, and analyzing trial metrics to optimize enrollment and retention. Travel to sites and meetings (40-50% US-based).

Lead CADD/SBDD strategy for discovery programs, translate structural insights into testable design hypotheses, apply CADD methods (docking, MD, FEP+), partner with structural biology, medicinal chemistry, DMPK and platform teams, and mentor scientists to accelerate S-DMTA cycles.

The Principal Data Scientist will lead the development of AI-powered data science tools, collaborating with cross-functional teams to enhance clinical research and optimize trials. Responsibilities include designing scalable solutions, ensuring software reliability, and communicating insights effectively.

The Director of Research Data Management will define and implement data management strategies, establish data standards, and lead data integration efforts that support drug discovery processes, partnering with various scientific teams.

The Principal Scientist to Associate Director will oversee analytical development for small molecules, manage CROs and CDMOs, ensure regulatory compliance, and develop strategies for analytical methods and documentation.

The Associate Director/Director of Biostatistics provides statistical support for clinical drug trials, oversees CRO activities, and ensures regulatory compliance for data submissions.

The Data Scientist will enhance the platforms, develop tools for clinical research, and ensure reliability of analytical solutions using software engineering best practices.

The Associate Director, Trial Master File oversees eTMF governance for clinical trials, ensuring compliance, quality, and timeliness in processes to support inspections and collaboration across functions.

The Associate Director, Program Management will manage late-stage clinical programs, ensuring timelines, budgets, and regulatory compliance are met while facilitating cross-functional collaboration.

The Senior Patent Agent will oversee the intellectual property portfolio, draft new applications, guide IP strategies, and support patent prosecution efforts.

The role focuses on computational chemistry, employing molecular dynamics and cheminformatics for small-molecule drug discovery and optimization. Collaborates with multidisciplinary teams to influence therapeutic design.

The Sr. Director of Commercial Supply Chain leads supply chain operations, ensuring steady drug supply, demand forecasting, and cross-functional collaboration for clinical and commercial programs.

The Associate Scientist/Scientist in DMPK will develop bioanalytical methods and analyze samples for small molecule projects, collaborating with cross-functional teams.

Lead global GLP/GMP Quality Assurance strategy to transition from clinical development to commercial readiness. Build and manage GMP QA and QC Compliance teams, oversee audits/inspections, ensure regulatory compliance (FDA, EMA, ICH, NMPA), manage vendor oversight of CROs/CMOs/CDMOs, drive QMS processes (deviations, CAPA, change control, OOS/OOT), and advise executive leadership on quality risk and inspection readiness.

Lead end-to-end semi-monthly payroll for US employees via ADP TotalSource, coordinate EMEA payroll, process off-cycle and equity taxable events, ensure payroll tax compliance and SOX controls, prepare payroll journal entries and reconciliations, review Ramp expense coding, support month-end close and external audit PBC documentation.

Lead sourcing, evaluating, and executing in-licensing, partnering, and transaction opportunities aligned with company priorities. Provide sell-side positioning expertise, drive diligence and valuation, prepare investment memos and presentations, and support negotiations and deal execution. Build and leverage external biopharma networks and partner with cross-functional teams to assess scientific, clinical, commercial, financial, legal, and IP considerations.

The Site Engagement Lead will manage participant recruitment and retention strategies for clinical trials, collaborate with teams, and improve engagement through educational resources and relationships.

The Director of Analytical Development leads analytical activities for late-stage drug development, ensuring compliance with regulatory standards and overseeing method development and qualification. Responsibilities include authoring submissions for regulatory filings and managing cross-functional teams and external partnerships in drug development.

Lead in vivo pharmacology studies, troubleshoot experimental challenges, ensure data integrity, and mentor junior scientists while supporting drug discovery projects.

Lead complex IT programs in R&D and enterprise functions, managing delivery across software development lifecycles. Ensure alignment between technology and business priorities for effective program execution.