Jobs at Sarepta Therapeutics

The Director of Analytical Development will lead the advancement of analytical methods for siRNA and antisense oligonucleotides, manage external manufacturing site activities, and oversee regulatory submissions while mentoring a team of scientists.

The Associate Director, HR Business Partner leads strategic people initiatives, partners with senior leaders, and drives organizational effectiveness at Sarepta. Key responsibilities include talent management, organizational design, change management, and employee engagement.

Responsible for inventory and manufacturing cost accounting: prepare journal entries, reconcile general ledger and inventory accounts, support audits, develop standard costs, analyze variances, assist with physical counts, maintain SOX controls, and improve processes across supply chain and manufacturing operations.

Co-manage Sarepta's global GxP training program: maintain compliant training systems (Veeva Training Vault), design and deliver GxP eLearning, manage SOPs and qualification records, support inspections, perform LMS validation/upgrades, generate reports, and provide cross‑functional training operations and end‑user support.

Lead pharmacovigilance (GVP) quality oversight and audit program; design and execute audit strategy; manage audit reports, CAPA, and remediation; support inspection readiness and regulatory interactions; review SOPs and QMS elements; collaborate cross-functionally to identify risks and ensure sustainable compliance.

Lead commercial reporting and operations for Commercial organization: build and maintain dashboards and Executive reports, manage contracted analysts, administer Tableau, partner with cross-functional teams (Sales Effectiveness, Patient Services, Data Management, Site Readiness), set reporting standards, manage delivery schedules, and support Veeva/CRM alignment and data stewardship.

Lead development and maintenance of lifecycle forecasting models and scenario analyses for Sarepta's in-line and pipeline therapies. Partner cross-functionally to produce demand forecasts, sensitivity analyses, and decision-ready insights to support commercial planning (S&OP, LRP, LEs), HCP targeting, and leadership/board discussions. Monitor market dynamics, drive ad hoc analyses, and improve forecasting capabilities and variance reporting.

Manage operational and logistical components of commercial training: plan and execute training programs, maintain online content and Veeva lifecycle, coordinate cross-functional stakeholders, manage contracts/POs, assign learning content, and support field training activities and communications.

Promote safe, effective use of Sarepta therapies across an assigned territory by building HCP relationships, executing consultative clinical selling, driving enrollment forms, educating on genetic testing and antibody assays, developing strategic account plans, and collaborating cross-functionally to remove barriers to care for Duchenne patients. Meet/exceed sales and enrollment goals and travel frequently within the region.

The Duchenne Nurse Educator educates healthcare providers, patients, and caregivers about Duchenne muscular dystrophy and infusion processes, ensuring support for medication compliance and conducting on-call triage support as needed.

As the Director of Biostatistics, you will lead statistical efforts in clinical trials, oversee statistical deliverables, and collaborate with cross-functional teams to enhance precision genetic medicine.

The Associate Director, Quantitative Clinical Pharmacology drives quantitative strategies and pharmacometrics analyses for drug development and regulatory strategies, requiring strong expertise in clinical pharmacology and PK/PD modeling.

Lead the Biometrics team to provide statistical strategies for clinical development and regulatory submissions while overseeing collaborations and ensuring compliance in statistical methodologies.

The Senior Scientist will assess developability of lead biologic molecules through evaluation and characterization, collaborating across teams to define attributes and stability assays.

Support planning and execution of international supply chain for commercial programs. Coordinate global distribution, inventory, import/export documentation, and trade compliance. Partner cross-functionally to resolve operational issues, perform scenario planning and risk mitigation, and drive process and system improvements while delivering accurate data and reporting.

Manage infrastructure, planning, tracking, and execution of outside-US (OUS) International Business initiatives. Coordinate cross-functional project plans and launches, run meetings and action-item follow-up, maintain tracking tools and reporting, manage vendors and contracts, and partner with Global Access and Patient Services to ensure compliant, scalable operations.

Lead SOX 404 compliance and support external financial reporting and technical accounting. Coordinate control documentation, testing, remediation, and audit interactions. Prepare and review SEC filings (10-Q, 10-K), XBRL, disclosures, and supporting schedules. Analyze complex and non-recurring transactions, develop accounting policies, and collaborate with FP&A, Legal, Investor Relations, and auditors to ensure accuracy and timely reporting.

Lead and execute GPV and GLP/GCLP vendor audits, develop audit plans and reports, review vendor responses, support GxP inspections, maintain audit schedules and records, and revise GxP quality documentation to ensure regulatory compliance.

Lead development of commercial field training strategy and capabilities, create and deliver scientific, product, and disease-state education, ensure promotional review/MLR compliance, implement virtual and in-person training delivery (national/regional), measure training impact, and collaborate cross-functionally to meet business needs.

Lead end-to-end process development for oligonucleotide and siRNA therapies from preclinical through commercialization. Define phase-appropriate strategies, scale-up, tech transfer, CDMO oversight, and QbD-aligned control strategies. Provide technical and regulatory support for CMC documentation, investigations, and validation readiness while collaborating across functions to enable clinical and commercial manufacturing.