Jobs at Sarepta Therapeutics

Design, build, and deploy scalable ML models for R&D and expand into clinical/regulatory use cases. Partner with cross-functional teams, ensure data availability and governance, evaluate vendor and internal solutions, and maintain explainability, traceability, and reproducibility within enterprise architecture.

The Senior Scientist will assess developability of lead biologic molecules through evaluation and characterization, collaborating across teams to define attributes and stability assays.

The Director will advocate for Sarepta's interests in state government affairs, managing relationships with officials, developing strategies, and ensuring compliance with state regulations while supporting the company's objectives in healthcare and legislative environments.

Design and develop global clinical drug supply operations, translating program requirements into compliant, timely supply chain plans; optimize packaging, labeling, distribution, inventory positioning, and temperature-controlled logistics; lead continuous improvement, process mapping, capacity planning, KPI dashboards, investigations, and CMO/vendor project management.

Lead and optimize MLR/material review processes across Veeva Vault, oversee forecasting and coordinator support, build dashboards and reports, manage vendor and coordinator activities, train cross-functional teams, support FDA submission workflows, and drive continuous process and system improvements.

Lead SOX 404 compliance and support external financial reporting and technical accounting. Coordinate control documentation, testing, remediation, and audit interactions. Prepare and review SEC filings (10-Q, 10-K), XBRL, disclosures, and supporting schedules. Analyze complex and non-recurring transactions, develop accounting policies, and collaborate with FP&A, Legal, Investor Relations, and auditors to ensure accuracy and timely reporting.

The Associate Director oversees global program management, ensuring project execution aligns with company strategies, manages risks, and communicates effectively with stakeholders.

Lead development of commercial field training strategy and capabilities, create and deliver scientific, product, and disease-state education, ensure promotional review/MLR compliance, implement virtual and in-person training delivery (national/regional), measure training impact, and collaborate cross-functionally to meet business needs.

Lead end-to-end process development for oligonucleotide and siRNA therapies from preclinical through commercialization. Define phase-appropriate strategies, scale-up, tech transfer, CDMO oversight, and QbD-aligned control strategies. Provide technical and regulatory support for CMC documentation, investigations, and validation readiness while collaborating across functions to enable clinical and commercial manufacturing.

Lead clinical pharmacology strategies and manage a team in drug development. Oversee translational and mechanistic modeling to inform clinical development.

The Associate Director, HR Business Partner leads strategic people initiatives, partners with senior leaders, and drives organizational effectiveness at Sarepta. Key responsibilities include talent management, organizational design, change management, and employee engagement.

Lead Data Manager manages clinical data management activities across studies, ensuring data quality and compliance while collaborating with cross-functional teams and vendors.

Responsible for inventory and manufacturing cost accounting: prepare journal entries, reconcile general ledger and inventory accounts, support audits, develop standard costs, analyze variances, assist with physical counts, maintain SOX controls, and improve processes across supply chain and manufacturing operations.

The Senior Manager of Cost Accounting & Manufacturing Operations oversees financial processes, product costing, inventory management, and compliance for manufacturing operations. The role involves collaboration with multiple departments and supervision of accounting practices related to inventory and clinical trials.

The Director, Market Access Marketing leads the development and execution of US reimbursement and payer access strategies, ensuring optimal product positioning across payers. This role involves collaboration with cross-functional teams and oversight of promotional materials while managing a budget and a marketing team.

The Director of Analytical Development will lead the advancement of analytical methods for siRNA and antisense oligonucleotides, manage external manufacturing site activities, and oversee regulatory submissions while mentoring a team of scientists.

The Duchenne Nurse Educator educates healthcare providers, patients, and caregivers about Duchenne Muscular Dystrophy therapies and manages patient support programs, collaborating closely with cross-functional teams.

The Duchenne Nurse Educator educates healthcare providers, patients, and caregivers about Duchenne muscular dystrophy and infusion processes, ensuring support for medication compliance and conducting on-call triage support as needed.

The Associate Director, Quantitative Clinical Pharmacology drives quantitative strategies and pharmacometrics analyses for drug development and regulatory strategies, requiring strong expertise in clinical pharmacology and PK/PD modeling.

The Senior Manager will lead global regulatory operations, ensure compliance in RIMS, and manage submissions to health authorities, improving processes and training users on RIMS.