Jobs at Flagship Pioneering

Supports executive search and talent acquisition operations across Flagship Pioneering and its portfolio companies. Responsibilities include coordinating searches, maintaining candidate data in Greenhouse, creating recruiting templates and documentation, preparing reports and dashboards, using AI-enabled tools to improve workflows, and providing timely stakeholder support. The role requires strong organization, communication, discretion, data accuracy, and the ability to manage multiple priorities in a fast-paced environment.

Lead the architecture and operation of AWS-based cloud, scientific data, and AI/ML infrastructure. Build reusable infrastructure-as-code, CI/CD, security, networking, observability, and environment-management patterns. Partner with cloud and data engineers, scientists, and computational biologists to enable reproducible workloads and scalable platforms. Diagnose complex cross-system failures, lead incident reviews, establish engineering standards, shape the infrastructure roadmap, and mentor engineers as a senior individual contributor.

Leads early research project management for a somatic genomics drug discovery platform. Establishes governance, integrated planning, reporting, budgeting, risk management, and portfolio visibility while coordinating cross-functional scientific and operational teams from disease ideation through target assessment and downstream development. Partners with research leadership, finance, and drug discovery teams to improve execution, resource planning, prioritization, and operational excellence in a growing biotech organization.

Lead development and deployment of AI/ML solutions for target discovery, translational research, biomarker identification, and scientific decision-making. Partner with scientists and engineering teams to build scalable workflows for complex biological and multimodal data, promote best practices, mentor colleagues, and recommend emerging AI technologies to accelerate research.

Lead development and scaling of cloning and construct generation capabilities, define cloning strategy, implement high-throughput DNA assembly and automation workflows, improve throughput and quality, partner cross-functionally, mentor scientists, and represent cloning capabilities externally to accelerate RNA-based agricultural product development.

Lead development of FL129's discovery platform by designing and testing custom target/variant libraries, adapting and optimizing screens for cell- or surface-displayed protein targets, ensuring high-quality data generation and documentation, translating experimental results into insights, and collaborating across experimental and computational teams to drive platform goals.

Lead development, training, validation, and application of generative chemistry and molecular models. Curate datasets and benchmarks, optimize workflows, collaborate with wet lab scientists, and translate experimental data into insights to shape the company's scientific direction.

Design, build, and iterate fixed-wing UAVs and autopilot systems; tune firmware and PID, develop C2/RF links, plan BVLOS operations, analyze flight logs, integrate sensors, document tests and SOPs for field deployments.

The Sr. Director will lead program management and operations for drug development, ensuring effective collaboration among teams and alignment with organizational goals.

Design, execute, and analyze high-throughput pooled FACS-based screening campaigns end-to-end. Build and optimize DNA/oligo libraries and lentiviral preparations, culture and screen primary-like cell models, prepare sorted populations for NGS, analyze barcode enrichment to call hits, and iterate with protein-engineering and translational teams to validate and improve the screening platform.

Design, build, and optimize membrane protein constructs and DNA/oligo libraries for high-throughput pooled screens. Perform large-scale molecular cloning, mammalian cell expression (including lentiviral transduction), assay development, and iterative design-build-test cycles. Troubleshoot folding/expression, partner with screening/translational teams, document workflows, and help shape scientific strategy and the protein-engineering function.

Lead creation and execution of visual communications across presentations, marketing collateral, digital and motion assets. Translate complex scientific and business concepts into clear visual narratives, develop scalable brand and presentation systems, use AI-enabled creative tools, and partner with cross-functional leaders to deliver polished, executive-ready materials under tight deadlines.

The Director/Senior Director of Compensation leads global compensation programs, collaborating with HR and finance to ensure competitive and equitable pay structures while managing compliance and operational efficiency.

The Director of Product Development will lead the creation of diagnostic assays from biological discoveries, focusing on assay optimization and team leadership while collaborating across disciplines for product readiness.

Manage participant recruitment and scheduling for onsite research visits: identify eligible candidates, contact and screen interest, schedule and confirm visits, send reminders and instructions, track communications and statuses, and serve as the primary pre-visit contact to minimize no-shows and flag recruitment or scheduling issues.

The Head of Capital Solutions for APAC will strengthen investor relations, drive fundraising efforts, and enhance Flagship's presence in the Asia-Pacific investment landscape.

Provide high-quality administrative and operational support to the Chief Scientific Officer and research leadership. Manage calendars, meetings, travel and expense reporting, prepare materials, plan events, coordinate visitors, troubleshoot minor IT issues, support office/lab moves, and assist with department communications and special projects.

Lead a team of Principal Software Engineers to set technical strategy, contribute to system designs, and drive delivery while remaining technically active.

The role includes developing cell-based and biochemical assays, collaborating on pharmacology projects, and assisting in data reporting to progress Abiologics' therapeutic pipeline.

Lead strategy and operations for two Origination teams to drive biotech company creation. Set priorities, track KPIs, manage cross-functional execution, allocate resources, enable collaboration with Flagship functions, and implement program management best practices and tools. Support portfolio leadership, prepare strategic briefings, guide hiring/onboarding, develop playbooks for ideation and launch, surface risks and mitigations, and foster team culture to accelerate value creation across early- to mid-stage life sciences companies.