Jobs at Dyne Therapeutics

Lead FP&A activities including budgeting, forecasting, financial modeling, variance and KPI analysis, and scenario planning. Own FP&A systems, reporting tools, and financial data warehouse development. Partner with Accounting, IT, and business leaders to deliver automated dashboards, actionable insights, and business cases supporting resource allocation, portfolio decisions, and board-level reporting.

The Director oversees and evolves the Quality Management System, embedding quality in operations and ensuring compliance with global regulations while managing audits and supplier quality.

The Senior Director of Program Management leads cross-functional teams in drug development, ensuring strategic alignment and execution while fostering collaboration and continuous improvement.

The Senior Director leads the development of reporting and analytics for clinical operations, integrating data for decision-making and optimizing resources using advanced analytics and AI.

The Receptionist manages front desk operations, supports administrative tasks, assists visitors, handles correspondence, and coordinates office supplies and events. Requires excellent interpersonal skills and ability to adapt in a dynamic environment.

Lead the Trial Master File (TMF) strategy, ensuring compliance and quality oversight, while managing TMF operations across clinical portfolios and collaborating with cross-functional teams.

The Director ensures effective operations within the US Affiliate, managing budgets, contracts, and cross-functional initiatives to support growth and alignment.

Senior HR leader responsible for enterprise learning, leadership development, manager excellence, onboarding, succession planning, and workforce capability. Partners with executive teams to design scalable blended learning, measure impact with analytics, drive culture and change initiatives, and build a high-performing L&D function to support Dyne's growth.

Lead biostatistical strategy and execution across clinical development programs. Design trials, author statistical sections and SAPs, oversee analyses and deliverables, support regulatory submissions and health authority interactions, manage CROs/vendors, mentor statisticians, and ensure submission-ready CDISC-compliant datasets, tables, listings, figures, and documentation.

The Director of Compliance ensures Dyne Therapeutics complies with laws, designs a global compliance program, and advises on commercial and regulatory matters. They lead risk assessments and collaborate with cross-functional teams while promoting a culture of integrity.

Lead strategy and execution of biologics CMC development from early-stage through clinical readiness. Drive process development, CDMO selection and technology transfer, author Module 3 content, ensure cGMP compliance, and provide cross-functional technical leadership to advance programs and optimize manufacturing cost and scalability.

Lead the development and execution of HCP marketing strategies for Myotonic Dystrophy, ensuring effective engagement and education while collaborating across various teams.

Lead US commercial enablement by designing incentive compensation, optimizing CRM and BI systems, building field operations infrastructure, coordinating cross-functional launch readiness, and scaling processes to improve field effectiveness and operational excellence.

Lead generation of market, customer, and data-driven insights to inform commercial strategy across rare neuromuscular pipeline. Own global forecasting, market research, competitive intelligence, dashboards/KPIs, and advanced analytics. Partner cross-functionally to guide launch planning, access, budgeting, and executive decision-making while ensuring data governance and vendor management.

The role involves process development and technology transfer for bioconjugates, managing external CDMO activities, and ensuring GMP manufacturing processes. The Senior Scientist will lead CMC activities, oversee drug substance development, and collaborate with cross-functional teams on product strategies for clinical evaluation.

Manage end-to-end cold chain logistics for clinical and commercial supply, coordinating shipments between CMOs, warehouses, 3PLs and couriers. Lead network re-supply, ensure GMP/GDP and trade compliance, develop SOPs, support commercial launch 3PL setup, monitor vendor performance, troubleshoot issues, and partner with cross-functional teams to maintain supply continuity and documentation.

The Director of HCP Marketing leads strategies for engaging healthcare providers in Duchenne Muscular Dystrophy, focusing on launch execution, cross-functional collaboration, and utilizing insights for improved performance.

Lead Dynes enterprise procurement function, building source-to-pay strategy, processes, systems, and supplier management. Drive high-value sourcing, negotiations, compliance, cross-functional partnership, reporting on savings and risks, and CSR/ESG procurement initiatives to support growth and operational goals.

The Director of Training leads training programs, oversees curriculum development, enhances employee capabilities, and collaborates cross-functionally to drive performance and commercial excellence.

Lead design, scaling, and governance of a global, inspection-ready Quality Management System (QMS) supporting commercial readiness. Own document control, records management, training/eDMS/LMS, eQMS implementation, compliance with ICH/FDA/EU standards, inspection readiness, quality metrics, and cross-functional embedding of quality practices.