Jobs at Axle Informatics

Conduct quantitative and qualitative analyses of programs, grants, administrative operations, and financial data. Develop evaluation methods, reconcile and validate information, perform cost-benefit analyses, prepare reports, assess workflows and data systems, and recommend improvements to organizational processes and efficiency. Coordinate studies with stakeholders, communicate findings, and support management decision-making at the NIH.

Build and maintain research data infrastructure connecting laboratory instruments, analysis pipelines, LIMS, repositories, databases, and cloud platforms. Develop ingestion and data transformation pipelines, manage metadata and persistent identifiers, deploy Kubernetes-based services, maintain CI/CD and infrastructure-as-code, and integrate AI/ML tools for data discovery. The role also evaluates data-management technologies, trains research staff, and produces technical documentation and procedures.

Program, integrate, calibrate, and maintain autonomous laboratory robots and instruments. Develop MADSci-based workflows, digital twins, scheduling, APIs, data integrations, testing, monitoring, safety interlocks, and failure recovery. Translate biological protocols into reliable automated processes, connect systems to LIMS and metadata pipelines, troubleshoot hardware and software, evaluate simulation tools, and train laboratory staff. The role requires hands-on robotics, Python software development, biological laboratory experience, and compliance with NIH/HHS security requirements.

Provides budget formulation and execution support for NIH financial operations, including cost tracking, expenditure monitoring, budget reporting, spending projections, and interagency agreement management. Develops Excel-based financial analyses using macros, formulas, and PivotTables; supports financial systems and process automation; resolves complex funding inquiries; and coordinates with the NIAID Budget Office on allocations, year-end close, and projections.

Provides independent federal grants management support for NIH across the full grant lifecycle, including application review, budget verification, compliance monitoring, award setup, financial reporting, post-award actions, records management, and closeout. Reviews applications and supporting documentation, tracks grants data in NIH systems, prepares reports and correspondence, identifies administrative or policy issues, and coordinates with internal and external stakeholders to ensure accurate, compliant, and timely grants administration.

Develops communications strategies and materials supporting public health preparedness and emergency response. Writes, proofreads, and edits business, technical, and scientific content; conducts media analysis; maintains websites and social media; monitors press coverage; builds media relationships; coordinates media engagements; and identifies outreach opportunities. The role is onsite in Washington, DC, with possible emergency response schedule flexibility or deployment.

Owns end-to-end product quality for an identity management system built with Node.js and Angular. Responsibilities include designing automated and manual tests, integrating Playwright or similar frameworks into CI/CD, applying AI-assisted testing, validating authentication and authorization flows, investigating defects, and providing occasional end-user support. The role collaborates with developers, product managers, and designers throughout Agile development while documenting risks, defects, test coverage, and support knowledge.

Coordinates program and project activities supporting government contracts, including deliverable tracking, reporting, documentation, SOP maintenance, employee onboarding, performance reviews, timesheets, travel, and training requests. Serves as a liaison among program staff, corporate teams, HR, leadership, and government stakeholders while ensuring compliance with deadlines, contract requirements, and organizational policies.

Manages scientific operational planning for high-containment research facilities, including laboratory modernization, campus master planning, space allocation, equipment lifecycle programs, renovation coordination, stakeholder engagement, workflow assessments, and leadership reporting. Supports BSL and ABSL laboratory operations while developing tracking applications and centralized tools for biosafety cabinets and scientific equipment.

Lead the platform engineering team while owning reliable, secure, and scalable cloud and container infrastructure. Manage Kubernetes operations, AWS architecture, DevSecOps practices, CI/CD, Terraform automation, observability, incident response, cost management, and infrastructure security. The role combines people leadership with hands-on architecture, troubleshooting, roadmap planning, and stakeholder collaboration in a hybrid DC Metro Area setting.

Leads a contracts administration team from post-award through closeout across government and commercial engagements. Oversees deadlines, compliance, KPIs, performance management, cross-functional coordination, subcontracting compliance, SAM reporting, and contract risk. Builds scalable procedures, implements automation and contract management systems, and resolves complex issues. Requires government contracting experience, FAR knowledge, team supervision, and process improvement expertise.

Designs, develops, deploys, configures, tests, and documents software throughout all phases of the software development life cycle using Java, J2EE, HTML, PL/SQL, T-SQL, and Unix.

Leads budgeting, forecasting, revenue and cash-flow analysis, contract profitability, workforce economics, backlog and funding analysis, and management reporting. Provides financial decision support to leadership, automates models and recurring reports, establishes KPI frameworks, and manages and develops the finance team. The role requires onsite work in Tysons, Virginia or Rockville, Maryland.

Leads daily accounting operations, including AP, AR, billing, payroll, general ledger, contract accounting, reconciliations, and month-end close. Manages and develops the accounting team, strengthens internal controls, supports audits, and ensures accurate financial records. Drives automation and process standardization to create scalable operations, resolve discrepancies, maintain audit readiness, and improve billing and reporting workflows.

Implements and monitors cybersecurity controls across Linux, Kubernetes, database, and model-serving environments. Builds monitoring, detection, vulnerability scanning, hardening automation, secrets management, network policy, access control, and evidence collection. Supports AI security tooling, documentation, testing, security reviews, continuous monitoring reports, and federal authorization activities. This early-career role includes hands-on training, certification support, and collaboration with AI and systems administration leads.

Build production AI retrieval and knowledge systems for rare disease research at NIH. Model biomedical ontologies in PostgreSQL, develop semantic search, retrieval-augmented services, ranking, evaluation, and observability, and deliver user interfaces with Next.js, React, and TypeScript. Deploy and operate services in on-premises and HPC Kubernetes environments, including GPU inference. Collaborate with NIH staff, clinicians, and researchers, and contribute to scientific publications.

Build and operate agentic AI systems for rare disease research, including multi-turn workflows, structured and validated outputs, tool calling, prompt testing, evaluation suites, asynchronous execution, streaming, observability, and failure handling. Collaborate with NIH staff, clinicians, geneticists, researchers, and patient communities to translate needs into reliable data models and system behavior. Own components through deployment, establish AI engineering standards, and contribute to scientific manuscripts, abstracts, and conference posters.

Leads multidisciplinary teams across data engineering, AI/ML, scientific computing, and modeling to build reliable biomedical research systems. Sets technical strategy, guides production data platforms, advances responsible AI, and establishes standards for reproducibility, governance, security, observability, and delivery. The role moves research prototypes into dependable production capabilities, develops technical leaders, supports federal proposals, and partners with scientists, engineers, security teams, and government stakeholders.

The Site Reliability Engineer designs monitoring frameworks, manages SLIs/SLOs, automates cloud infrastructure, ensures compliance, and promotes SRE best practices.

Manage drafting, negotiation, and administration of federal contracts and subcontracts; maintain contract records and compliance with FAR/DFARS; monitor vendor performance; support audits and kickoff meetings; identify and apply AI/automation to improve contract workflows.