Jobs at Axle Informatics

Conduct analytical development and characterization of vaccines, monoclonal antibodies, recombinant proteins, and other biologics using mass spectrometry, LC-MS, and electrophoresis. Perform sample preparation, data acquisition, analysis, interpretation, documentation, method development, optimization, troubleshooting, qualification, and transfer. Maintain detailed laboratory records, communicate findings, support multiple projects, and collaborate with multidisciplinary scientific teams in a vaccine research environment.

Manages the lifecycle of SOPs, Work Instructions, and training modules for NIH aseptic processing and biosafety facilities. Responsibilities include drafting, revision control, approval routing, controlled distribution, expiration monitoring, archival, SME reviews, and regulatory alignment. Tracks employee training completion, links training to controlled documents, maintains auditable records, generates compliance reports, and supports internal and external audits.

Provides scientific program administration and strategic coordination for the NHLBI HIV/AIDS Program. Responsibilities include managing scientific initiatives, portfolio and performance analyses, funding and budget activities, grant coding, reports, databases, websites, meetings, working groups, literature reviews, presentations, and stakeholder communications across NIH offices and partner organizations. The role also supports policy compliance, program evaluation, funding announcements, and coordination of HIV/AIDS research priorities related to heart, lung, blood, and sleep disorders.

Designs, develops, deploys, configures, tests, and documents software throughout all phases of the software development life cycle using Java, J2EE, HTML, PL/SQL, T-SQL, and Unix.

Performs biological sample preparation, cryo-EM imaging, negative staining, image analysis, and TEM operation for infectious disease research. Troubleshoots and maintains microscopy instruments, collaborates with NIH investigators, supports CLEM and FIB-SEM capabilities, maintains rigorous records, trains facility users, and contributes to lab safety and equipment upkeep.

Provides executive administrative support to NIH’s National Library of Medicine, including calendar management, meeting coordination, travel planning, procurement, records maintenance, data entry, reporting, and office workflow support. The role manages federal travel and administrative systems, prepares documents and presentations, tracks budgets and personnel actions, ensures regulatory compliance, and coordinates communications, meetings, committees, and special projects.

Leads budgeting, forecasting, revenue and cash-flow analysis, contract profitability, workforce economics, backlog and funding analysis, and management reporting. Provides financial decision support to leadership, automates models and recurring reports, establishes KPI frameworks, and manages and develops the finance team. The role requires onsite work in Tysons, Virginia or Rockville, Maryland.

Leads daily accounting operations, including AP, AR, billing, payroll, general ledger, contract accounting, reconciliations, and month-end close. Manages and develops the accounting team, strengthens internal controls, supports audits, and ensures accurate financial records. Drives automation and process standardization to create scalable operations, resolve discrepancies, maintain audit readiness, and improve billing and reporting workflows.

Implements and monitors cybersecurity controls across Linux, Kubernetes, database, and model-serving environments. Builds monitoring, detection, vulnerability scanning, hardening automation, secrets management, network policy, access control, and evidence collection. Supports AI security tooling, documentation, testing, security reviews, continuous monitoring reports, and federal authorization activities. This early-career role includes hands-on training, certification support, and collaboration with AI and systems administration leads.

Leads hybrid cloud and on-premises IT operations across Linux and Windows environments. Responsibilities include ITIL-based incident, problem, change, and release management; systems hardening, patching, vulnerability remediation, automation, monitoring, and observability. The role supports AI/ML and GPU-enabled workloads, manages operational readiness and documentation, and mentors systems engineers while driving reliability, scalability, and infrastructure improvements.

Build production AI retrieval and knowledge systems for rare disease research at NIH. Model biomedical ontologies in PostgreSQL, develop semantic search, retrieval-augmented services, ranking, evaluation, and observability, and deliver user interfaces with Next.js, React, and TypeScript. Deploy and operate services in on-premises and HPC Kubernetes environments, including GPU inference. Collaborate with NIH staff, clinicians, and researchers, and contribute to scientific publications.

Build and operate agentic AI systems for rare disease research, including multi-turn workflows, structured and validated outputs, tool calling, prompt testing, evaluation suites, asynchronous execution, streaming, observability, and failure handling. Collaborate with NIH staff, clinicians, geneticists, researchers, and patient communities to translate needs into reliable data models and system behavior. Own components through deployment, establish AI engineering standards, and contribute to scientific manuscripts, abstracts, and conference posters.

Leads multidisciplinary teams across data engineering, AI/ML, scientific computing, and modeling to build reliable biomedical research systems. Sets technical strategy, guides production data platforms, advances responsible AI, and establishes standards for reproducibility, governance, security, observability, and delivery. The role moves research prototypes into dependable production capabilities, develops technical leaders, supports federal proposals, and partners with scientists, engineers, security teams, and government stakeholders.

The Site Reliability Engineer designs monitoring frameworks, manages SLIs/SLOs, automates cloud infrastructure, ensures compliance, and promotes SRE best practices.

Manage drafting, negotiation, and administration of federal contracts and subcontracts; maintain contract records and compliance with FAR/DFARS; monitor vendor performance; support audits and kickoff meetings; identify and apply AI/automation to improve contract workflows.

The Entomologist will conduct research on malaria, manage data, collaborate with partners, and contribute to protocol development and project coordination.

The Senior Full Stack Developer will design and build cloud-native applications, using TypeScript, Node.js, and Angular while working in an agile environment.

The Electron Microscopy Specialist prepares biological samples, conducts experiments, operates EM instruments, supports research projects, and trains lab members, focusing on generating imaging data for infectious disease research.

The role involves developing AI/ML models to predict organoid growth and optimizing differentiation protocols through computational methods, collaborating with experimental teams.

Build scalable full-stack applications using TypeScript, Node.js, and Angular; design and implement RESTful services; create responsive web interfaces; and write unit and end-to-end tests. Collaborate in an Agile team on prototyping, testing, code reviews, and cloud-native applications using containers and orchestration tools.