Jobs at Arrowhead Pharmaceuticals

Lead strategic planning and operational excellence for Global Operations and Product Delivery. Own portfolio prioritization, governance, long-range planning, trade policy, risk and network strategy, supplier/partnership management, change management, budget/metrics, and cross-functional alignment to maximize asset value and organizational readiness.

The Executive Director will lead AI and enterprise data strategy, enhance operational efficiency, ensure regulatory compliance, and drive AI adoption across the organization.

The Executive Director of Regulatory Affairs will lead regulatory submissions for clinical trials, ensuring compliance and managing relationships with regulatory agencies. Responsibilities include strategy development, document preparation, and oversight of regulatory operations.

Lead design and execution of Arrowhead's global trade compliance and operating model. Own import/export policies, risk controls, customs/classification, sanctions compliance, and trade-related strategy for international market activation. Partner cross-functionally to enable launches, tariff mitigation, logistics provider qualification, and scalable systems (including SAP and trade management tools). Build and lead a global trade team, engage regulators, and drive continuous improvement and KPI-driven monitoring across R&D, manufacturing, clinical, and commercial supply chains.

Support revenue accounting under ASC 606 for partnership and commercial contracts. Prepare revenue models, journal entries, reconciliations, and month-end close tasks. Support SEC disclosures (10-Q/10-K), billing/invoicing, gross-to-net activities, SOX controls, and external audit deliverables. Partner with FP&A, Legal, Clinical, and IT to validate revenue inputs and ensure accurate, SOX-compliant financial reporting.

Draft, negotiate, evaluate, and execute a wide range of contracts; ensure contract data accuracy in the CLM; advise internal stakeholders on risk and compliance; prepare amendments and notices; collaborate with cross-functional teams to support business goals in a fast-paced, regulated biotech environment.

Lead design, development, and execution of fit-for-purpose clinical biomarker assays to support pharmacodynamics and predict clinical response. Evaluate new technologies, manage CRO partnerships and assay transfers, collaborate cross-functionally to advance early-stage programs, mentor junior staff, and oversee GCLP-regulated clinical sample testing documentation.

Review, analyze and approve global clinical site and vendor budgets and contracts for Phase I-IV trials. Perform FMV benchmarking, site payment reconciliations, maintain master site documentation, track site performance, identify routine cost savings, partner with CROs, legal and internal stakeholders, and support process improvements and ad-hoc finance projects.

Lead development, implementation, and optimization of a global GxP QMS to ensure regulatory compliance and PAI readiness. Oversee document control, training, CAPA, audits, change and risk management. Build and mentor a QMS team, partner cross-functionally with manufacturing, QC, supply chain, and regulatory affairs, and drive continuous improvement and quality culture.

Contribute to preclinical histology by planning and executing tissue collection, processing, embedding, sectioning, and staining (H&E, special stains, IHC/IF). Maintain audit-ready records in LIMS/ELN, perform microscopy and imaging, support method validation (e.g., RNAscope), and operate/maintain histology instrumentation while communicating results to study teams.

The Manager will lead peer-to-peer programs and manage congress planning, ensuring compliance, overseeing budgets, and collaborating with cross-functional teams in marketing.

The Director of Strategic Sourcing and Procurement will lead the procurement function, drive cost efficiency, establish procurement processes, and manage vendor relationships while supporting R&D and Commercial functions.

Independently review laboratory and external data for accuracy, completeness, and GMP compliance. Investigate and document discrepancies, support release and stability reviews, audit/inspection readiness, and collaborate with labs and CDMOs. Mentor junior reviewers and recommend process improvements and digital/trend-analysis tools.

Provide supplier quality assurance for material lifecycle management including supplier evaluation/qualification, change control, documentation review, risk-based material assessments, supplier non-conformance/SCAR oversight, quality metrics reporting, and authoring/updating supplier-related quality system documents to support GMP manufacturing and clinical/commercial programs.

The Scientist I, Quality Control will conduct analytical testing for drug substances/products, support GLP Toxicology testing, and mentor co-workers, focusing on cGMP compliance and utilizing various analytical techniques.

The Revenue Accounting Manager will oversee partnership accounting, manage revenue recognition processes, and ensure compliance with ASC 606 and SOX controls. The role involves collaboration with FP&A, managing month-end closing processes, and preparing revenue-related disclosures.

The Director of IT Infrastructure leads the strategy and operations of the company's IT infrastructure, managing cloud platforms, team development, budget, compliance, and system reliability.

The Senior Scientist I, DMPK will lead preclinical DMPK studies, manage data analysis, and ensure regulatory compliance for RNAi therapeutics.

The Corporate Counsel will provide legal guidance on drug pricing, market access, and reimbursement, while supporting internal stakeholders and managing outside counsel as required.

The Manager of Clinical Programming will support clinical studies by developing software for data management, collaborating with teams, and ensuring quality in programming outputs.