Top Remote Python Jobs in Jacksonville, FL

Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.

Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.

As a Senior Software Engineer, you'll enhance ClickHouse's Python integrations, drive AI integration strategies, and collaborate with open-source communities, requiring deep expertise in data engineering and AI applications.

The Senior Python Developer will enhance commerce and communication infrastructure by developing features, collaborating with stakeholders, ensuring system reliability, and integrating with third-party tools, while maintaining high-performance standards.

As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.

The Forward Deployed Engineer will serve as a technical bridge between clients and engineering teams, writing custom code and integrations, while ensuring customer success with Socket's security platform through strong relationships and expert technical guidance.

Design, develop, deploy, monitor, and support APIs and system integrations (Salesforce, REST, third-party). Work directly with clients to gather requirements, troubleshoot and optimize integrations, operate solutions in AWS, collaborate with teams, and mentor junior developers.

Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.

Build and maintain Django-based web applications, design RESTful APIs, implement frontend features (HTML/CSS/JS), optimize performance and security, collaborate with cross-functional teams throughout the development lifecycle.

The Senior Software Engineer will build a large-scale data ingestion and classification system using web scraping, data processing, and search technologies, overseeing data extraction from various sources and developing search capabilities.

As a Staff Software Engineer, you’ll lead the design and reliability of Duetto's data lakehouse, evolving data systems using Python and AWS, ensuring data quality, and implementing AI-driven solutions.

Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.

Build and maintain API services for a decentralized exchange, design and implement trade routing logic for optimized cross-chain swaps, integrate features with cross-functional teams, monitor system performance and reliability, and troubleshoot trade execution and API issues.

Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.

Design, implement, and maintain SaaS features using Python and React on AWS. Lead system design, code reviews, CI/CD pipelines, AI-integrated development (LLMs and AI coding agents), prompt engineering, testing (Cypress), and on-call production support. Mentor teammates and ensure secure, scalable, well-documented software.

We are seeking a software engineer to build and validate resilient distributed systems, enhance CI pipelines, and improve testing strategies for cloud applications.

The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.