Technical Product Lead, Manufacturing Execution System (MES)
Oxford Nanopore
Oxford Nanopore has developed a new generation of nanopore-based sensing technology for faster, information-rich, accessible and affordable molecular analysis. The technology is used to understand and characterise the biology of humans, animals, plants, bacteria, viruses, and diseases such as cancer. By enabling biological insights, we strive to improve life on Earth and beyond.
The Role
We are seeking a Technical Product Lead to take ownership of our Manufacturing Execution System (MES), supporting the manufacture of our sequencing products.
This role will be responsible for the technical integration, operational effectiveness, compliance, and technical coherence of our newly commissioned MES SaaS platform, NoMuda VisualFactory.
Reporting to the Manufacturing Platform Owner, you will work closely with our in house development teams responsible for bespoke systems supporting tracking, traceability, and control across complex manufacturing processes.
The MES platform is central to our digital manufacturing strategy, enabling manufacturing process engineers to safely and consistently self configure workflows while ensuring compliance with GAMP standards and seamless integration with internal systems.
You will collaborate closely with NoMuda implementation and support teams, internal software engineering teams, manufacturing process engineers across Production and Tech Transfer, and Quality, Validation, and Regulatory stakeholders.
Key Responsibilities
MES Ownership & Operations
- Drive an effective, coherent integration between existing manufacturing systems and the new MES, NoMuda Visual Factory
- Own the operation and lifecycle management of the NoMuda VisualFactory MES platform
- Ensure platform availability, performance, security, and data integrity of the MES
- Ensure operational processes, including support, incident management, change control, and release coordination, conforms to ONT's internal processes
- Act as the primary technical owner for incidents and enhancements for VisualFactory, and engagement with NoMuda
Technical Coherence
- Maintain technical coherence across VisualFactory and integrated in-house systems
- Define and govern integration patterns, data flows, APIs, and event-driven interactions
- Identify and mitigate technical, architectural, and operational risks throughout the system’s lifecycle
Configuration Strategy & SME Enablement
- Collaborate with the Manufacturing Platform Owner to define and implement patterns for self-service configuration by process engineers, to ensure solutions are scalable, maintainable, and compliant
Continuous Improvement & Data-Driven Decisions
- Work alongside software development teams to guide design decisions and implementation approaches
- Identify and implement process improvements and operational efficiencies
- Collect and analyse platform usage statistics and user feedback
- Monitor key performance indicators (KPIs) for platform health, adoption, and value
Required Skills & Experience
Technical & Platform Experience
- Experience managing complex, integrated digital manufacturing platforms
- Experience managing SaaS platforms
- Solid understanding of software architecture, integrations, and data management
- Experience working with software development teams (Agile or hybrid environments)
- Experience working directly with manufacturing process engineers
Manufacturing & Collaboration Skills
- Experience working directly with manufacturing SMEs and process engineers
- Experience working collaboratively with SaaS vendors
- Strong stakeholder engagement and communication skills across technical and non-technical audiences
Desirable Experience
- Strong understanding of manufacturing systems in regulated environments
- Experience of complex medical device, biologics, biopharma manufacturing or development.
- Experience working with NoMuda VisualFactory or similar low-code MES platforms
- Experience with compliance standards such as GAMP, ISO 13485, or computer system validation (CSV) in medical device or life sciences environments
Please note that no terminology in this advert is intended to discriminate on the grounds of a person's gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.
#LI-Hybrid
#LI-MO1
Oxford Nanopore Technologies: Our goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology for faster, information rich, accessible and affordable molecular analysis. The first application is DNA/RNA sequencing, and the technology is in development for the analysis of other types of molecules including proteins. The technology is used to understand and characterise the biology of humans and diseases such as cancer, plants, animals, bacteria, viruses, and whole environments. With a thriving culture of ambition and strong innovation goals, Oxford Nanopore is a UK headquartered company with global operations and customers in more than 125 countries.
Skills Required
- Experience managing complex, integrated digital manufacturing platforms
- Experience managing SaaS platforms
- Solid understanding of software architecture, integrations, and data management
- Experience working directly with manufacturing process engineers
- Experience working collaboratively with SaaS vendors
Oxford Nanopore Technologies Compensation & Benefits Highlights
The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Oxford Nanopore Technologies and has not been reviewed or approved by Oxford Nanopore Technologies.
-
Fair & Transparent Compensation — Pay is considered good to above average across many roles, with employer-provided ranges visible for several U.S. commercial and applications positions and company materials emphasizing market‑competitive base pay. Commercial and some senior technical posts, particularly in the U.S., are positioned as competitive and often paired with strong variable components.
-
Equity Value & Accessibility — All‑employee share plans in the UK and a U.S. employee stock purchase plan indicate broad access to equity as part of total reward. Company communications highlight attractive bonus and share plans that add meaningful upside beyond base pay.
-
Healthcare Strength — U.S. roles indicate strong health insurance and core protections, while official materials and country overviews reference private medical coverage and wellbeing support. These elements position the health package as a notable strength alongside cash compensation.
Oxford Nanopore Technologies Insights
What We Do
Our goal is to enable the analysis of anything, anywhere, by anyone. We have developed the world’s first and only nanopore DNA and RNA sequencing platform. It’s a new generation of sequencing technology — the only one to offer: scalability to portable or ultra-high throughput formats, real-time data delivery, and the ability to elucidate rich biological data. We are aiming to disrupt the way that biological analyses are currently performed, and open up new applications that have a profound, positive impact on society. Our devices offer real-time analysis, for rapid insights, in fully scalable formats — from pocket to population scale — and the technology is being used in more than 100 countries worldwide. Founded in 2005 as a spin-out from the University of Oxford, the company now employs more than 600 people from multiple disciplines including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market.
