Technical Operations Manager

Posted Yesterday
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Barnard Castle, Durham, England, GBR
In-Office
Senior level
Healthtech • Biotech • Pharmaceutical
The Role
Lead technical operations for a UK pharmaceutical manufacturing site, managing production, quality, safety and technical support. Provide technical leadership for process, equipment and facility issues, manage risks across sterile processing and utilities, drive investigations/CAPAs, support GMP and audit readiness, coach teams, and deliver continuous improvement to ensure reliable, compliant supply.
Summary Generated by Built In

Technical Operations Manager

Closing Date: 2nd July 2026 (COB)

Business Introduction
We manufacture and supply reliable, high-quality medicines and vaccines to meet patients’ needs and drive our performance.
Our network of 37 medicines and vaccines manufacturing sites delivered 1.7 billion packs of medicines and 409 million vaccine doses in 2024 to help make a positive impact on the health of millions of people. Our supply chain is not just core to our operations; it’s vital to bringing our innovations to patients as quickly, efficiently and effectively as possible. Technology is transforming how we manufacture medicines and vaccines, enabling us to increase the speed, quality and scale of product supply.
We need the very best minds and capability to help us on our journey to make more complex products, harnessing the power of smart manufacturing technologies including robotics, digital solutions and artificial intelligence to deliver for patients.
Position Summary
You will lead technical operations within a UK manufacturing site. You will manage day-to-day production, quality and safety while working closely with engineering, quality and supply chain colleagues. You will coach and develop people and lead improvement work to make operations more efficient and reliable. We value clear and practical leadership, curiosity, and a focus on developing others. This role offers visible career growth, meaningful impact and the chance to help GSK unite science, technology and talent to get ahead of disease together.
Responsibilities
This role will provide YOU the opportunity to lead key activities to progress YOUR career.

These responsibilities include some of the following:

Lead the technical support model for base business operations, ensuring production teams are supported to meet safety, quality and supply requirements.

Provide technical leadership and prioritisation for production issues requiring process, equipment or facility expertise.

Manage base business risks across sterile processing, aseptic behaviours, critical utilities, facilities and process controls.

Partner with operations and technical teams to resolve escalated issues, restore operations in a controlled manner, and monitor process and facility health through data and trends.

Ensure technical support activity aligns with audit readiness, GMP, EHS, data integrity and site compliance standards.

Support robust investigations, deviations and CAPAs while building technical capability, maintaining effective standards, and providing governance, escalation and performance reporting.
Why You?
Basic Qualification
We are seeking professionals with the following required skills and qualifications to help us achieve our goals
- Significant experience managing operations in a regulated pharmaceutical manufacturing environment.
- Experience working with cross-functional teams: engineering, quality and supply chain.
- Demonstrable track record of leading teams, coaching and managing performance.
- Experience delivering continuous improvement or productivity projects.
- Strong problem solving and decision-making skills in a technical setting.
- Clear communication and stakeholder management across levels.
Preferred Qualification
If you have the following characteristics, it would be a plus
- Degree or vocational qualification in engineering, science or a technical discipline.
- Knowledge of lean manufacturing, Six Sigma or other improvement methodologies.
- Experience with new product introductions, scale-up or facility transfers.
- Familiarity with electronic batch records or manufacturing execution systems.
- Experience managing shift-based teams and complex rostering.
Working model
This role is on-site at Barnard Castle. Candidates should be prepared to work from the site and collaborate closely with colleagues on the shop floor.
What we value in you
You are practical and calm under pressure. You set clear expectations and develop people through coaching and feedback. You act with integrity and put safety and quality first. You balance pace with rigour and make decisions based on evidence. You bring energy and a willingness to learn.
Apply now
If this role matches your experience and ambitions, we would like to hear from you. Please apply and tell us how your skills and values match this opportunity. We welcome applicants who bring varied experiences and perspectives and who support an inclusive workplace.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.


GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.


People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.


GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.


We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.


Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at [email protected] where you can also request a call.


Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a  Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive


Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.


Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

Skills Required

  • Significant experience managing operations in a regulated pharmaceutical manufacturing environment.
  • Experience working cross-functionally with engineering, quality and supply chain teams.
  • Proven track record of leading teams, coaching and managing performance.
  • Experience delivering continuous improvement or productivity projects.
  • Strong problem solving and technical decision-making skills.
  • Clear communication and stakeholder management across levels.
  • On-site work at Barnard Castle and ability to collaborate on the shop floor.
  • Degree or vocational qualification in engineering, science or a technical discipline.
  • Knowledge of Lean manufacturing, Six Sigma or other improvement methodologies.
  • Experience with new product introductions, scale-up or facility transfers.
  • Familiarity with electronic batch records or manufacturing execution systems.
  • Experience managing shift-based teams and complex rostering.

GSK Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about GSK and has not been reviewed or approved by GSK.

  • Strong & Reliable Incentives Compensation is characterized as including strong salary and perks, with annual bonuses and long-term incentives contributing materially to total rewards. Recognition and performance-linked rewards are described as a consistent component of the package.
  • Healthcare Strength Health coverage is presented as comprehensive, spanning medical, dental, vision, disability, life insurance, and mental health benefits. The breadth of coverage is repeatedly framed as a standout element of the overall rewards experience.
  • Retirement Support Retirement offerings are described as robust, anchored by a 401(k) plan and additional savings vehicles such as employee stock purchase programs. Employer contributions and savings options are portrayed as meaningful supports for long-term financial security.

GSK Insights

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The Company
HQ: Brentford
105,615 Employees
Year Founded: 2000

What We Do

A science-led global healthcare company with a special purpose: to help people do more, feel better, live longer. We have three global businesses that research, develop and manufacture innovative pharmaceutical medicines, vaccines and consumer healthcare products. We aim to bring differentiated, high-quality and needed healthcare products to as many people as possible, with our three global businesses, scientific and technical know-how and talented people.

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