Systems Engineer II (PCR/qPCR/Sequencing/troubleshhoting)

Reposted 5 Days Ago
Be an Early Applicant
Santa Clara, CA, USA
In-Office
57-57 Hourly
Senior level
HR Tech • Information Technology • Professional Services • Consulting
The Role
Hands-on role optimizing and validating single-molecule NGS workflows: perform nucleic acid extraction, library prep, sequencing, run experiments, troubleshoot instruments and assays, apply DoE and statistical analysis, develop test cases, document results, and collaborate across assay, instrumentation, software, and bioinformatics teams.
Summary Generated by Built In

Our client, a world leader in biotechnology and gene therapy, is looking for an “Systems Engineer II” based in Santa Clara, CA.

 

Job Duration: Long Term Contract (Possibility Of Extension)

Pay Rate : $57/hr on W2

 

Company Benefits: Medical, Dental, Vision, Paid Sick leave, 401K

 

Client is seeking a hands-on Systems Engineer II to support the development and integration of next-generation sequencing (NGS) solutions. This role will work with the Single Molecule Sequencing platform to optimize workflows, perform wet-lab experiments, troubleshoot system and assay issues, and support verification and validation activities.

 

Key Responsibilities

  • Design, execute, analyze, and document experiments supporting NGS feasibility, development, integration, verification, and validation.
  • Perform nucleic acid extraction, sample preparation, library preparation, and sequencing experiments.
  • Optimize sequencing workflows and operating protocols.
  • Troubleshoot instrument, assay, and workflow failures using root cause analysis.
  • Develop and execute test cases based on product requirements.
  • Apply statistical analysis and Design of Experiments (DoE) methods to interpret data and improve sequencing performance.
  • Collaborate with assay, instrumentation, software, bioinformatics, and systems engineering teams.
  • Maintain accurate laboratory records and support continuous improvement of sequencing performance, reliability, throughput, and reproducibility.

 

Required Qualifications

  • Bachelor’s degree with 5+ years of relevant experience, or Master’s degree with 1–3+ years of relevant experience in science, engineering, chemistry, or a related field.
  • Hands-on experience with PCR, nucleic acid extraction, DNA sequencing, sample preparation, library preparation, and/or NGS.
  • Experience using Python, MATLAB, Git, or similar tools for data analysis or automation.
  • Knowledge of statistical analysis, including JMP, regression, and ANOVA.
  • Experience with Design of Experiments (DoE) and statistical process control.
  • Strong troubleshooting, root cause analysis, data analysis, and technical documentation skills.

 

 

If interested, please send us your updated resume at

[email protected]/[email protected]

 

 

 



Skills Required

  • Bachelor's degree with 5+ years relevant experience or Master's degree with 1-3+ years in science, engineering, chemistry, or related field
  • Hands-on experience with PCR, nucleic acid extraction, DNA sequencing, sample preparation, library preparation, and/or NGS
  • Experience using Python, MATLAB, Git, or similar tools for data analysis or automation
  • Knowledge of statistical analysis including JMP, regression, and ANOVA
  • Experience with Design of Experiments (DoE) and statistical process control
  • Strong troubleshooting, root cause analysis, data analysis, and technical documentation skills
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The Company
Year Founded: 2009

What We Do

Dawar Consulting Inc. is a professional services and staff augmentation firm specializing in IT consulting, workforce solutions, and HCM/HRIS services. They provide technology and business consulting, project delivery, and IT support to help clients achieve their strategic goals. With expertise across IT, Engineering, and Finance, they deliver best-in-class workforce solutions and innovative strategies to drive operational efficiency and business success.

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