Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
The Digital Workplace AI Intern will support Arrowhead Pharmaceuticals’ efforts to advance its corporate AI program by designing and deploying intelligent search and automation agents across enterprise platforms. This internship offers hands-on experience working with Microsoft Copilot and AI agent technologies to improve knowledge discovery, productivity, and digital workflows across functions such as People Services, Research & Development, and Information Systems & Infrastructure (IS&I). The intern will collaborate with technical teams and business partners to develop AI-powered solutions that enhance how employees access information and complete everyday tasks.
This is an 11-week Summer Internship Program paying $21.00 per hour for students pursuing a Bachelor's Degree and $23.00 per hour for students pursuing a Master's Degree. This role requires full-time, onsite work five days per week at the designated location.
Responsibilities
- Design, develop, and deploy custom Microsoft Copilot AI agents using tools such as Microsoft Copilot Studio and other low-code/no-code platforms.
- Build AI-powered search agents that operate across SharePoint sites for People Services, Research & Development, and IS&I, as well as the Freshservice ticketing system.
- Collaborate with Digital Workplace team members and business partners to identify AI use cases and gather requirements.
- Integrate AI agents with the Microsoft 365 ecosystem, including Teams, SharePoint, and Outlook, to support intelligent automation, knowledge retrieval, and task assistance
- Test, iterate, and document AI agents to ensure reliability, security, and compliance within a regulated pharmaceutical environment.
- Assist in evaluating AI agent performance and recommend enhancements to improve usability and impact.
- Contribute ideas to enhance the overall digital workplace experience through responsible AI adoption.
Requirements
- Currently pursuing a Bachelor’s or Master’s degree in Computer Science, Information Systems, Data Science, AI/ML, Software Engineering, or a related field.
- Strong verbal and written communication skills.
- Excellent problem-solving and analytical skills.
- Ability to collaborate effectively with technical and non-technical stakeholders.
- Proficiency in Microsoft Office applications.
Preferred:
- Strong interest in generative AI, large language models, and workplace productivity tools.
- Familiarity with Microsoft 365, particularly Copilot, Teams, Power Platform, or Copilot Studio.
- Experience with low-code/no-code development platforms.
- Interest in enterprise search, automation, or digital transformation.
- Curiosity and initiative to explore emerging AI capabilities responsibly in a regulated environment.
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.
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What We Do
Arrowhead Pharmaceuticals is a clinical stage, Nasdaq listed (ticker ARWR) company developing medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, our therapies trigger the RNA interference mechanism to induce rapid, deep and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Our RNAi-based therapeutics are at the leading edge of genetic-based therapy with the potential to bring life changing treatments for patients. Our Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. The TRiM platform builds on more than a decade of work on actively targeted drug delivery and offers several advantages including simplified manufacturing and reduced costs; multiple routes of administration; and potential for improved safety. Our employees are nimble, science-driven, and innovative professionals. A career at Arrowhead offers the opportunity to collaborate with top notch scientists to rapidly discover and develop RNAi-based therapeutics to add to our growing pipeline. Research and development activities are located in Madison, WI. Our R&D group includes fully-integrated capabilities for chemistry, biology, and toxicology. Madison is an exciting and sophisticated city that includes state government, the flagship campus of the University of Wisconsin, and major research organizations. Our HQ, clinical and regulatory operations are located in Pasadena, CA. Just north of Los Angeles and resting in the foothills of the San Gabriel Mountains, Pasadena is known for its natural scenic beauty, vibrant cultural and academic environment and rich architectural setting.









